JPWO2021193982A5 - - Google Patents
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- Publication number
- JPWO2021193982A5 JPWO2021193982A5 JP2022510782A JP2022510782A JPWO2021193982A5 JP WO2021193982 A5 JPWO2021193982 A5 JP WO2021193982A5 JP 2022510782 A JP2022510782 A JP 2022510782A JP 2022510782 A JP2022510782 A JP 2022510782A JP WO2021193982 A5 JPWO2021193982 A5 JP WO2021193982A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- halogen atom
- represented
- phenyl
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020058414 | 2020-03-27 | ||
| JP2020058414 | 2020-03-27 | ||
| PCT/JP2021/014251 WO2021193982A1 (ja) | 2020-03-27 | 2021-03-26 | 神経細胞変性阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021193982A1 JPWO2021193982A1 (https=) | 2021-09-30 |
| JPWO2021193982A5 true JPWO2021193982A5 (https=) | 2024-08-02 |
| JP7840054B2 JP7840054B2 (ja) | 2026-04-03 |
Family
ID=77892307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022510782A Active JP7840054B2 (ja) | 2020-03-27 | 2021-03-26 | 神経細胞変性阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230120205A1 (https=) |
| EP (1) | EP4129293A4 (https=) |
| JP (1) | JP7840054B2 (https=) |
| CN (1) | CN115335058B (https=) |
| CA (1) | CA3172328A1 (https=) |
| WO (1) | WO2021193982A1 (https=) |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050070524A1 (en) * | 2003-06-06 | 2005-03-31 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
| ZA200709038B (en) * | 2005-04-13 | 2009-01-28 | Neuraxon Inc | Substituted indole compounds having nos inhibitory activity |
| JP5693951B2 (ja) * | 2007-04-24 | 2015-04-01 | アストラゼネカ エービー | プロテインキナーゼの阻害剤 |
| EP2137164B1 (en) * | 2007-04-24 | 2015-08-26 | AstraZeneca AB | Inhibitors of protein kinases |
| EP2137163B1 (en) * | 2007-04-24 | 2015-03-18 | AstraZeneca AB | Inhibitors of protein kinases |
| ES2579949T3 (es) * | 2010-02-05 | 2016-08-17 | Heptares Therapeutics Limited | Derivados de 1,2,4-triazin-4-amina |
| US20130079345A1 (en) * | 2010-03-22 | 2013-03-28 | Bayer Intellectual Property Gmbh | Pharmaceutically active disubstituted triazine derivatives |
| TWI555737B (zh) * | 2011-05-24 | 2016-11-01 | 拜耳知識產權公司 | 含有硫醯亞胺基團之４－芳基－ｎ－苯基－１，３，５－三氮雜苯－２－胺 |
| EP2561867A1 (en) * | 2011-08-22 | 2013-02-27 | Lead Discovery Center GmbH | CDK9 inhibitors in the treatment of midline carcinoma |
| JP6473077B2 (ja) | 2013-03-21 | 2019-02-20 | 国立大学法人京都大学 | 神経分化誘導用の多能性幹細胞 |
| CN107530430A (zh) * | 2015-01-13 | 2018-01-02 | 国立大学法人京都大学 | 用于预防和/或治疗肌萎缩性侧索硬化症的药剂 |
| CN105085427B (zh) * | 2015-08-21 | 2018-06-05 | 中国科学院广州生物医药与健康研究院 | 一类苯并[d]异恶唑类化合物及其应用 |
| GB201605126D0 (en) * | 2016-03-24 | 2016-05-11 | Univ Nottingham | Inhibitors and their uses |
| CN107304189A (zh) * | 2016-04-18 | 2017-10-31 | 北京大学 | 一种三嗪化合物及其制备方法和应用 |
| JP6959632B2 (ja) | 2017-05-15 | 2021-11-02 | 学校法人近畿大学 | 筋萎縮性側索硬化症又は前頭側頭型認知症の予防又は治療剤 |
| CN110582491B (zh) * | 2017-06-30 | 2023-09-29 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| AU2018342105B2 (en) * | 2017-09-26 | 2023-11-16 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
| EP4234553A3 (en) * | 2018-05-09 | 2023-09-06 | Design Therapeutics, Inc. | Methods and compounds for the treatment of genetic disease |
| JP7135692B2 (ja) | 2018-10-05 | 2022-09-13 | ニプロ株式会社 | 排液システム |
-
2021
- 2021-03-26 CA CA3172328A patent/CA3172328A1/en active Pending
- 2021-03-26 CN CN202180024013.0A patent/CN115335058B/zh active Active
- 2021-03-26 EP EP21774856.5A patent/EP4129293A4/en not_active Withdrawn
- 2021-03-26 WO PCT/JP2021/014251 patent/WO2021193982A1/ja not_active Ceased
- 2021-03-26 US US17/906,127 patent/US20230120205A1/en not_active Abandoned
- 2021-03-26 JP JP2022510782A patent/JP7840054B2/ja active Active
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