JPWO2021163434A5 - - Google Patents
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- JPWO2021163434A5 JPWO2021163434A5 JP2022548811A JP2022548811A JPWO2021163434A5 JP WO2021163434 A5 JPWO2021163434 A5 JP WO2021163434A5 JP 2022548811 A JP2022548811 A JP 2022548811A JP 2022548811 A JP2022548811 A JP 2022548811A JP WO2021163434 A5 JPWO2021163434 A5 JP WO2021163434A5
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- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
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- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062975544P | 2020-02-12 | 2020-02-12 | |
| US62/975,544 | 2020-02-12 | ||
| PCT/US2021/017794 WO2021163434A1 (en) | 2020-02-12 | 2021-02-12 | Hla class i-restricted t cell receptors against ras with g12d mutation |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023528112A JP2023528112A (ja) | 2023-07-04 |
| JP2023528112A5 JP2023528112A5 (https=) | 2024-02-28 |
| JPWO2021163434A5 true JPWO2021163434A5 (https=) | 2024-02-28 |
| JP7832111B2 JP7832111B2 (ja) | 2026-03-17 |
Family
ID=74860472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548811A Active JP7832111B2 (ja) | 2020-02-12 | 2021-02-12 | G12d突然変異rasに対するhlaクラスi拘束性t細胞受容体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20230080742A1 (https=) |
| EP (1) | EP4103597A1 (https=) |
| JP (1) | JP7832111B2 (https=) |
| KR (1) | KR20220143867A (https=) |
| CN (1) | CN115279784A (https=) |
| AU (1) | AU2021221138A1 (https=) |
| BR (1) | BR112022015888A2 (https=) |
| CA (1) | CA3168015A1 (https=) |
| CL (1) | CL2022002208A1 (https=) |
| CO (1) | CO2022012922A2 (https=) |
| CU (1) | CU20220044A7 (https=) |
| GB (1) | GB2609760B (https=) |
| IL (1) | IL295252A (https=) |
| MX (1) | MX2022009654A (https=) |
| TW (1) | TWI900528B (https=) |
| WO (1) | WO2021163434A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202540156A (zh) * | 2020-10-02 | 2025-10-16 | 美國衛生與公眾服務部 | 針對含有g13d突變之ras之hla第ii類限制性dq t細胞受體 |
| IL305393A (en) | 2021-02-25 | 2023-10-01 | Alaunos Therapeutics Inc | Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof |
| US20250145950A1 (en) | 2022-02-01 | 2025-05-08 | Alaunos Therapeutics, Inc. | Methods for Activation and Expansion of T Cells |
| EP4673167A1 (en) * | 2023-02-27 | 2026-01-07 | Adaptive Biotechnologies Corp. | Therapeutic t cell receptors targeting kras g12d |
| CN118812698A (zh) * | 2023-04-19 | 2024-10-22 | 香雪生命科学技术(广东)有限公司 | 一种识别kras突变的高亲和力t细胞受体及其应用 |
| CN118852403A (zh) * | 2023-04-26 | 2024-10-29 | 北京鼎成肽源生物技术有限公司 | 靶向kras突变的tcr分子和细胞及其应用 |
| WO2025006196A1 (en) | 2023-06-28 | 2025-01-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors targeting ras with g12d, g12r, or g12v mutation |
| WO2026057812A1 (en) * | 2024-09-12 | 2026-03-19 | Medigene Immunotherapies Gmbh | T-cell receptor variant against mkras 7-16 g12d |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003265948B8 (en) | 2002-09-06 | 2009-09-03 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy |
| WO2007017201A1 (en) * | 2005-08-05 | 2007-02-15 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt Gmbh | Generation of antigen specific t cells |
| US8383099B2 (en) | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| WO2012129201A1 (en) | 2011-03-22 | 2012-09-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| MX384919B (es) | 2014-11-26 | 2025-03-14 | Us Health | Receptores de células t de kras anti-mutado. |
| CN108395479B (zh) * | 2017-02-06 | 2021-07-16 | 高军 | 一种有关kras基因突变的t细胞受体 |
| EP3720478A1 (en) * | 2017-12-04 | 2020-10-14 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Hla class i-restricted t cell receptors against mutated ras |
-
2021
- 2021-02-12 US US17/799,163 patent/US20230080742A1/en active Pending
- 2021-02-12 KR KR1020227031175A patent/KR20220143867A/ko active Pending
- 2021-02-12 TW TW110105194A patent/TWI900528B/zh active
- 2021-02-12 GB GB2211733.7A patent/GB2609760B/en active Active
- 2021-02-12 BR BR112022015888A patent/BR112022015888A2/pt unknown
- 2021-02-12 AU AU2021221138A patent/AU2021221138A1/en active Pending
- 2021-02-12 CU CU2022000044A patent/CU20220044A7/es unknown
- 2021-02-12 WO PCT/US2021/017794 patent/WO2021163434A1/en not_active Ceased
- 2021-02-12 CA CA3168015A patent/CA3168015A1/en active Pending
- 2021-02-12 CN CN202180014038.2A patent/CN115279784A/zh active Pending
- 2021-02-12 JP JP2022548811A patent/JP7832111B2/ja active Active
- 2021-02-12 MX MX2022009654A patent/MX2022009654A/es unknown
- 2021-02-12 IL IL295252A patent/IL295252A/en unknown
- 2021-02-12 EP EP21710730.9A patent/EP4103597A1/en active Pending
-
2022
- 2022-08-12 CL CL2022002208A patent/CL2022002208A1/es unknown
- 2022-09-12 CO CONC2022/0012922A patent/CO2022012922A2/es unknown
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