JPWO2021163477A5 - - Google Patents

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JPWO2021163477A5
JPWO2021163477A5 JP2022549088A JP2022549088A JPWO2021163477A5 JP WO2021163477 A5 JPWO2021163477 A5 JP WO2021163477A5 JP 2022549088 A JP2022549088 A JP 2022549088A JP 2022549088 A JP2022549088 A JP 2022549088A JP WO2021163477 A5 JPWO2021163477 A5 JP WO2021163477A5
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Japan
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seq
amino acid
acid sequence
chain
val
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JP2022549088A
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JP2023526149A (ja
JP2023526149A5 (https=
JP7735285B2 (ja
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Priority claimed from PCT/US2021/017852 external-priority patent/WO2021163477A1/en
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JP2022549088A 2020-02-14 2021-02-12 G12v突然変異rasに対するhlaクラスi拘束性t細胞受容体 Active JP7735285B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062976655P 2020-02-14 2020-02-14
US62/976,655 2020-02-14
US202063060340P 2020-08-03 2020-08-03
US63/060,340 2020-08-03
PCT/US2021/017852 WO2021163477A1 (en) 2020-02-14 2021-02-12 Hla class i-restricted t cell receptors against ras with g12v mutation

Publications (4)

Publication Number Publication Date
JP2023526149A JP2023526149A (ja) 2023-06-21
JP2023526149A5 JP2023526149A5 (https=) 2024-02-26
JPWO2021163477A5 true JPWO2021163477A5 (https=) 2024-02-26
JP7735285B2 JP7735285B2 (ja) 2025-09-08

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JP2022549088A Active JP7735285B2 (ja) 2020-02-14 2021-02-12 G12v突然変異rasに対するhlaクラスi拘束性t細胞受容体

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US (1) US20230082787A1 (https=)
EP (1) EP4103598A1 (https=)
JP (1) JP7735285B2 (https=)
KR (1) KR20220143875A (https=)
CN (1) CN115315441A (https=)
AU (1) AU2021220957A1 (https=)
BR (1) BR112022015897A2 (https=)
CA (1) CA3167382A1 (https=)
GB (1) GB2610311B (https=)
MX (1) MX2022009825A (https=)
TW (1) TWI902755B (https=)
WO (1) WO2021163477A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL305393A (en) 2021-02-25 2023-10-01 Alaunos Therapeutics Inc Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof
EP4334361A1 (en) 2021-05-05 2024-03-13 Immatics Biotechnologies GmbH Antigen binding proteins specifically binding prame
US20250145950A1 (en) 2022-02-01 2025-05-08 Alaunos Therapeutics, Inc. Methods for Activation and Expansion of T Cells
WO2023232785A1 (en) * 2022-05-30 2023-12-07 Hs Diagnomics Gmbh Common tumor-specific t cell receptors
CN118852452A (zh) * 2023-04-28 2024-10-29 北京鼎成肽源生物技术有限公司 靶向kras g12突变的tcr分子和细胞及其应用
WO2025056681A1 (en) * 2023-09-15 2025-03-20 Medigene Immunotherapies Gmbh T-CELL RECEPTOR AGAINST mKRAS7-16 G12V AND G12C

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003265948B8 (en) 2002-09-06 2009-09-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy
US8383099B2 (en) 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
WO2012129201A1 (en) 2011-03-22 2012-09-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
MX384919B (es) 2014-11-26 2025-03-14 Us Health Receptores de células t de kras anti-mutado.
JP7185524B2 (ja) * 2015-09-15 2022-12-07 アメリカ合衆国 Hla-cw8拘束性の変異krasを認識するt細胞受容体
US20170319638A1 (en) * 2016-05-06 2017-11-09 Virttu Biologics Limited Treatment of cancer
EP3684799A1 (en) 2017-09-20 2020-07-29 The U.S.A. as represented by the Secretary, Department of Health and Human Services Hla class ii restricted t cell receptors against mutated ras
EP3720478A1 (en) * 2017-12-04 2020-10-14 The United States of America, as represented by the Secretary, Department of Health and Human Services Hla class i-restricted t cell receptors against mutated ras
EP3731861A1 (en) * 2017-12-29 2020-11-04 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft T cell receptors for tumor specific proteasome splice variants and uses thereof

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