JPWO2021117861A5 - - Google Patents
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- Publication number
- JPWO2021117861A5 JPWO2021117861A5 JP2021564057A JP2021564057A JPWO2021117861A5 JP WO2021117861 A5 JPWO2021117861 A5 JP WO2021117861A5 JP 2021564057 A JP2021564057 A JP 2021564057A JP 2021564057 A JP2021564057 A JP 2021564057A JP WO2021117861 A5 JPWO2021117861 A5 JP WO2021117861A5
- Authority
- JP
- Japan
- Prior art keywords
- tablet according
- disintegrant
- cellulose
- mpa
- viscosity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007884 disintegrant Substances 0.000 claims 15
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 13
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 13
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 13
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 10
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 10
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 10
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 10
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 9
- 239000011230 binding agent Substances 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 9
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 9
- 238000005469 granulation Methods 0.000 claims 6
- 230000003179 granulation Effects 0.000 claims 6
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 239000007888 film coating Substances 0.000 claims 4
- 238000009501 film coating Methods 0.000 claims 4
- GFICWFZTBXUVIG-SCSAIBSYSA-N imeglimin Chemical compound C[C@H]1NC(N(C)C)=NC(N)=N1 GFICWFZTBXUVIG-SCSAIBSYSA-N 0.000 claims 4
- 229950005411 imeglimin Drugs 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 1
- 239000008109 sodium starch glycolate Substances 0.000 claims 1
- 229940079832 sodium starch glycolate Drugs 0.000 claims 1
- 229920003109 sodium starch glycolate Polymers 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022097803A JP7671265B2 (ja) | 2019-12-13 | 2022-06-17 | 製造性及び溶出性に優れた小型錠剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019225718 | 2019-12-13 | ||
| JP2019225718 | 2019-12-13 | ||
| PCT/JP2020/046253 WO2021117861A1 (ja) | 2019-12-13 | 2020-12-11 | 製造性及び溶出性に優れた小型錠剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022097803A Division JP7671265B2 (ja) | 2019-12-13 | 2022-06-17 | 製造性及び溶出性に優れた小型錠剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021117861A1 JPWO2021117861A1 (https=) | 2021-06-17 |
| JPWO2021117861A5 true JPWO2021117861A5 (https=) | 2022-06-02 |
| JP7093473B2 JP7093473B2 (ja) | 2022-06-29 |
Family
ID=76330003
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564057A Active JP7093473B2 (ja) | 2019-12-13 | 2020-12-11 | 製造性及び溶出性に優れた小型錠剤 |
| JP2022097803A Active JP7671265B2 (ja) | 2019-12-13 | 2022-06-17 | 製造性及び溶出性に優れた小型錠剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022097803A Active JP7671265B2 (ja) | 2019-12-13 | 2022-06-17 | 製造性及び溶出性に優れた小型錠剤 |
Country Status (5)
| Country | Link |
|---|---|
| JP (2) | JP7093473B2 (https=) |
| KR (1) | KR20220113942A (https=) |
| CN (1) | CN114945370A (https=) |
| TW (1) | TW202135826A (https=) |
| WO (1) | WO2021117861A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116440075B (zh) * | 2023-06-01 | 2025-05-06 | 苏州中化药品工业有限公司 | 一种干混悬剂及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2896158B1 (fr) * | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'inhibiteurs de la hmg-coa reductase. |
| FR2896157B1 (fr) * | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline. |
| US8592370B2 (en) | 2008-12-12 | 2013-11-26 | Poxel S.A.S. | Combination of insulin with triazine derivatives |
| TWI436768B (zh) | 2010-06-09 | 2014-05-11 | Poxel | 第２型糖尿病之治療 |
| KR20190120430A (ko) * | 2012-01-06 | 2019-10-23 | 엘셀릭스 테라퓨틱스 인코포레이티드 | 바이구아나이드 조성물 및 대사 장애를 치료하는 방법 |
| JP5775223B2 (ja) * | 2012-09-05 | 2015-09-09 | テイカ製薬株式会社 | 口腔内速崩壊性錠剤用造粒物 |
| JPWO2017170858A1 (ja) * | 2016-03-31 | 2019-02-14 | インターセプト ファーマシューティカルズ， インコーポレイテッド | 溶出性に優れた経口製剤 |
| JP6854162B2 (ja) * | 2017-03-17 | 2021-04-07 | ライオン株式会社 | 錠剤 |
| CA3103324A1 (en) * | 2018-06-14 | 2019-12-19 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
-
2020
- 2020-12-11 CN CN202080085661.2A patent/CN114945370A/zh active Pending
- 2020-12-11 JP JP2021564057A patent/JP7093473B2/ja active Active
- 2020-12-11 WO PCT/JP2020/046253 patent/WO2021117861A1/ja not_active Ceased
- 2020-12-11 TW TW109143784A patent/TW202135826A/zh unknown
- 2020-12-11 KR KR1020227019247A patent/KR20220113942A/ko not_active Withdrawn
-
2022
- 2022-06-17 JP JP2022097803A patent/JP7671265B2/ja active Active
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