JPWO2021110061A5 - - Google Patents
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- Publication number
- JPWO2021110061A5 JPWO2021110061A5 JP2022532785A JP2022532785A JPWO2021110061A5 JP WO2021110061 A5 JPWO2021110061 A5 JP WO2021110061A5 JP 2022532785 A JP2022532785 A JP 2022532785A JP 2022532785 A JP2022532785 A JP 2022532785A JP WO2021110061 A5 JPWO2021110061 A5 JP WO2021110061A5
- Authority
- JP
- Japan
- Prior art keywords
- lys
- hyp
- dopa
- pro
- thr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 22
- 229960004502 levodopa Drugs 0.000 claims 20
- 150000001413 amino acids Chemical group 0.000 claims 14
- 229960003638 dopamine Drugs 0.000 claims 12
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 claims 8
- MHUWZNTUIIFHAS-CLFAGFIQSA-N dioleoyl phosphatidic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC MHUWZNTUIIFHAS-CLFAGFIQSA-N 0.000 claims 8
- 206010061218 Inflammation Diseases 0.000 claims 7
- 238000009472 formulation Methods 0.000 claims 7
- 230000004054 inflammatory process Effects 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 239000002671 adjuvant Substances 0.000 claims 4
- 239000003085 diluting agent Substances 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- 238000011200 topical administration Methods 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- KSEQKLUIMYFIKJ-UHFFFAOYSA-N 3-cyclohexa-1,5-dien-1-ylprop-2-enoic acid Chemical compound OC(=O)C=CC1=CCCC=C1 KSEQKLUIMYFIKJ-UHFFFAOYSA-N 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- DEFJQIDDEAULHB-IMJSIDKUSA-N L-alanyl-L-alanine Chemical compound C[C@H](N)C(=O)N[C@@H](C)C(O)=O DEFJQIDDEAULHB-IMJSIDKUSA-N 0.000 claims 1
- QOOWRKBDDXQRHC-BQBZGAKWSA-N L-lysyl-L-alanine Chemical compound OC(=O)[C@H](C)NC(=O)[C@@H](N)CCCCN QOOWRKBDDXQRHC-BQBZGAKWSA-N 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002500 effect on skin Effects 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 208000014617 hemorrhoid Diseases 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2019/122391 | 2019-12-02 | ||
| CNPCT/CN2019/122391 | 2019-12-02 | ||
| PCT/CN2020/133436 WO2021110061A1 (en) | 2019-12-02 | 2020-12-02 | Peptides and their use in the treatment of inflammation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023503380A JP2023503380A (ja) | 2023-01-27 |
| JPWO2021110061A5 true JPWO2021110061A5 (https=) | 2023-12-11 |
| JP2023503380A5 JP2023503380A5 (https=) | 2023-12-11 |
Family
ID=76221459
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022532785A Pending JP2023503380A (ja) | 2019-12-02 | 2020-12-02 | ペプチド及び炎症の治療におけるそれらの使用 |
| JP2022532756A Pending JP2023503374A (ja) | 2019-12-02 | 2020-12-02 | 新規なペプチドと多糖類とのコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022532756A Pending JP2023503374A (ja) | 2019-12-02 | 2020-12-02 | 新規なペプチドと多糖類とのコンジュゲート |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20240218016A1 (https=) |
| EP (2) | EP4069713A4 (https=) |
| JP (2) | JP2023503380A (https=) |
| KR (2) | KR20220117256A (https=) |
| CN (2) | CN114929283A (https=) |
| AU (2) | AU2020396109A1 (https=) |
| CA (2) | CA3160167A1 (https=) |
| TW (2) | TW202128729A (https=) |
| WO (2) | WO2021110061A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4665372A1 (en) * | 2023-02-13 | 2025-12-24 | EnliTISA (Shanghai) Pharmaceutical Co., Ltd. | New multi-functional oligopeptides |
| WO2024260465A1 (en) * | 2023-06-22 | 2024-12-26 | Enlitisa (Shanghai) Pharmaceutical Co., Ltd. | New multi-functional oligopeptides |
| WO2025195444A1 (en) | 2024-03-20 | 2025-09-25 | Enlitisa (Shanghai) Pharmaceutical Co., Ltd. | New use of peptides derived from vasoactive intestinal peptide |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02500082A (ja) * | 1987-03-12 | 1990-01-18 | ジェネックス・コーポレーション | 遺伝子操作された生物による生物粘着物質前駆体タンパク質類似体の生産 |
| US5229490A (en) * | 1987-05-06 | 1993-07-20 | The Rockefeller University | Multiple antigen peptide system |
| US4908404A (en) * | 1988-08-22 | 1990-03-13 | Biopolymers, Inc. | Synthetic amino acid-and/or peptide-containing graft copolymers |
| WO1996039128A1 (en) * | 1995-06-06 | 1996-12-12 | Hemosphere, Inc. | Protein particles for therapeutic and diagnostic use |
| US5616311A (en) * | 1991-01-15 | 1997-04-01 | Hemosphere, Inc. | Non-crosslinked protein particles for therapeutic and diagnostic use |
| AU5910099A (en) * | 1998-09-09 | 2000-04-03 | United States Surgical Corporation | Recombinant bioadhesive protein analogs comprising hydroxyproline |
| EE200300089A (et) * | 2000-09-08 | 2005-02-15 | Gryphon Therapeutics, Inc. | Sünteetilised erütropoeesi stimuleerivad valgud, nende valmistamismeetodid ning kasutamine |
| CU23011A1 (es) * | 2000-11-03 | 2004-12-17 | Ct Ingenieria Genetica Biotech | Método de obtención de estructuras antigénicas quemétodo de obtención de estructuras antigénicas que potencian la reactividad cruzada específica y su potencian la reactividad cruzada específica y su uso en formulaciones uso en formulaciones |
| EP1735456A4 (en) * | 2004-02-27 | 2011-11-16 | Univ Northwestern | POLYMERIC COMPOSITION AND ASSOCIATED METHOD OF USE |
| WO2007124593A1 (en) * | 2006-05-02 | 2007-11-08 | Universite Laval | Branched peptide amplification and uses thereof |
| WO2009001220A2 (en) * | 2007-06-26 | 2008-12-31 | Universitetet I Oslo | Functionalization of microscopy probe tips |
| CN103140262A (zh) * | 2010-11-15 | 2013-06-05 | 雅芳产品公司 | 生物功能锚定的长效的化妆品 |
| JP6202669B2 (ja) * | 2013-04-26 | 2017-09-27 | 国立研究開発法人国立循環器病研究センター | ペプチド及びその複合体、組織修復用スキャフォールド及びその表面処理方法、並びに表面処理液又は処理液のセット |
| KR101677097B1 (ko) * | 2015-03-18 | 2016-11-18 | 포항공과대학교 산학협력단 | 내부 장기의 접합 및 누공, 천공 또는 문합부 누출 치료용 접착 실란트 |
| SG10201909629PA (en) * | 2015-04-17 | 2019-11-28 | Symic Ip Llc | Bioconjugates and uses thereof |
| EP3326640B1 (en) * | 2015-07-20 | 2021-08-25 | Jiangyin Bengt I. Samuelsson Institute of Life Science Co., Ltd. | Applications of mussel adhesive protein product in treatment and prevention of diseases related to melanin |
| KR102468519B1 (ko) * | 2015-07-20 | 2022-11-21 | 장인 벵트 아이. 사무엘손 인스티튜트 오브 라이프 사이언스 컴퍼니 리미티드 | 피부 염증의 억제에서의 홍합 접착 단백질 제품 및 이의 적용 |
| WO2017028025A1 (zh) * | 2015-08-14 | 2017-02-23 | 江阴市本特塞缪森生命科学研究院有限公司 | 贻贝粘蛋白产品及其抑制粘膜炎症的应用 |
| WO2017088177A1 (zh) * | 2015-11-27 | 2017-06-01 | 江阴市本特塞缪森生命科学研究院有限公司 | 贻贝粘蛋白产品及其预防和抑制神经炎症的应用 |
| KR101807593B1 (ko) * | 2015-12-30 | 2017-12-11 | 포항공과대학교 산학협력단 | 흉터 최소화 상처 재생 촉진용 재조합 폴리펩타이드 및 이를 포함하는 생체 접착 소재 |
| AR110299A1 (es) * | 2016-12-02 | 2019-03-13 | Sanofi Sa | Conjugados que comprenden un agonista dual de glp-1 / glucagón, un conector y ácido hialurónico |
| MX2020000029A (es) * | 2017-07-05 | 2020-08-06 | Jiangyin Mucocare Pharmaceutical Co Ltd | Formulaciones topicas que comprenden montelukast y combinaciones con proteinas adhesivas del mejillon. |
| JP7198785B2 (ja) * | 2017-07-05 | 2023-01-04 | ジャンイン ユスン ファーマシューティカル カンパニー，リミテッド | ペプチドの抗炎症的使用 |
| KR102010051B1 (ko) * | 2017-09-20 | 2019-08-12 | 주식회사 포스코 | 카테콜 치환된 음이온성 고분자로부터 형성된 코아세르베이트, 이를 포함하는 접착제 및 이의 제조방법 |
| CA3130653A1 (en) * | 2018-03-09 | 2019-09-12 | Valitor, Inc. | Multivalent peptide conjugates for sustained intra-articular treatment of joint inflammation |
| JP7742226B2 (ja) * | 2018-05-28 | 2025-09-19 | ジャンイン ユスン ファーマシューティカル カンパニー，リミテッド | 新たな医薬品使用 |
| CN111601618A (zh) * | 2018-09-14 | 2020-08-28 | 江阴贝瑞森制药有限公司 | 孟鲁司特与肽的新缀合物 |
-
2020
- 2020-12-02 CA CA3160167A patent/CA3160167A1/en active Pending
- 2020-12-02 AU AU2020396109A patent/AU2020396109A1/en active Pending
- 2020-12-02 US US17/781,571 patent/US20240218016A1/en active Pending
- 2020-12-02 JP JP2022532785A patent/JP2023503380A/ja active Pending
- 2020-12-02 EP EP20896452.8A patent/EP4069713A4/en active Pending
- 2020-12-02 KR KR1020227022784A patent/KR20220117256A/ko active Pending
- 2020-12-02 AU AU2020396818A patent/AU2020396818A1/en active Pending
- 2020-12-02 KR KR1020227022746A patent/KR20220116468A/ko active Pending
- 2020-12-02 EP EP20897392.5A patent/EP4069715A4/en active Pending
- 2020-12-02 TW TW109142488A patent/TW202128729A/zh unknown
- 2020-12-02 WO PCT/CN2020/133436 patent/WO2021110061A1/en not_active Ceased
- 2020-12-02 JP JP2022532756A patent/JP2023503374A/ja active Pending
- 2020-12-02 WO PCT/CN2020/133438 patent/WO2021110063A1/en not_active Ceased
- 2020-12-02 CN CN202080083154.5A patent/CN114929283A/zh active Pending
- 2020-12-02 TW TW109142487A patent/TW202133882A/zh unknown
- 2020-12-02 CN CN202080083112.1A patent/CN114929726A/zh active Pending
- 2020-12-02 CA CA3160127A patent/CA3160127A1/en active Pending
- 2020-12-02 US US17/781,543 patent/US20230113836A1/en active Pending
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