JPWO2021097057A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021097057A5 JPWO2021097057A5 JP2022527081A JP2022527081A JPWO2021097057A5 JP WO2021097057 A5 JPWO2021097057 A5 JP WO2021097057A5 JP 2022527081 A JP2022527081 A JP 2022527081A JP 2022527081 A JP2022527081 A JP 2022527081A JP WO2021097057 A5 JPWO2021097057 A5 JP WO2021097057A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- disease
- cycloalkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025126773A JP2025160375A (ja) | 2019-11-12 | 2025-07-30 | Ｃｆｔｒ活性の欠損が介在する状態を治療するための５員ヘテロアリールアミノスルホンアミド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962934293P | 2019-11-12 | 2019-11-12 | |
| US62/934,293 | 2019-11-12 | ||
| PCT/US2020/060180 WO2021097057A1 (en) | 2019-11-12 | 2020-11-12 | 5-membered heteroarylaminosulfonamides for treating conditions mediated by deficient cftr activity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025126773A Division JP2025160375A (ja) | 2019-11-12 | 2025-07-30 | Ｃｆｔｒ活性の欠損が介在する状態を治療するための５員ヘテロアリールアミノスルホンアミド |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023500408A JP2023500408A (ja) | 2023-01-05 |
| JPWO2021097057A5 true JPWO2021097057A5 (https=) | 2023-11-20 |
| JP2023500408A5 JP2023500408A5 (https=) | 2023-11-20 |
| JP7721517B2 JP7721517B2 (ja) | 2025-08-12 |
Family
ID=73740547
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022527081A Active JP7721517B2 (ja) | 2019-11-12 | 2020-11-12 | Ｃｆｔｒ活性の欠損が介在する状態を治療するための５員ヘテロアリールアミノスルホンアミド |
| JP2025126773A Pending JP2025160375A (ja) | 2019-11-12 | 2025-07-30 | Ｃｆｔｒ活性の欠損が介在する状態を治療するための５員ヘテロアリールアミノスルホンアミド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025126773A Pending JP2025160375A (ja) | 2019-11-12 | 2025-07-30 | Ｃｆｔｒ活性の欠損が介在する状態を治療するための５員ヘテロアリールアミノスルホンアミド |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20240002374A1 (https=) |
| EP (1) | EP4058439A1 (https=) |
| JP (2) | JP7721517B2 (https=) |
| KR (1) | KR20220115829A (https=) |
| CN (1) | CN115003659B (https=) |
| AU (1) | AU2020384279A1 (https=) |
| BR (1) | BR112022009185A2 (https=) |
| CA (1) | CA3158057A1 (https=) |
| CL (1) | CL2022001245A1 (https=) |
| CO (1) | CO2022007953A2 (https=) |
| EC (1) | ECSP22046050A (https=) |
| IL (1) | IL292966A (https=) |
| JO (1) | JOP20220105A1 (https=) |
| MX (1) | MX2022005809A (https=) |
| PE (1) | PE20221461A1 (https=) |
| PH (1) | PH12022551139A1 (https=) |
| WO (1) | WO2021097057A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7214743B2 (ja) | 2018-02-15 | 2023-01-30 | バーテックス ファーマシューティカルズ インコーポレイテッド | 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターとしての大環状分子、それらの医薬組成物、嚢胞性線維症の治療におけるそれらの使用、及びそれらの製造方法 |
| UY38630A (es) | 2019-04-03 | 2020-10-30 | Vertex Pharma | Agentes moduladores del regulador de la conductancia transmembrana de la fibrosis quística |
| TWI867024B (zh) | 2019-08-14 | 2024-12-21 | 美商維泰克斯製藥公司 | 囊腫纖維化跨膜傳導調節蛋白之調節劑 |
| TWI899097B (zh) | 2019-08-14 | 2025-10-01 | 美商維泰克斯製藥公司 | 製備cftr調節劑之方法 |
| WO2021030552A1 (en) | 2019-08-14 | 2021-02-18 | Vertex Pharmaceuticals Incorporated | Crystalline forms of cftr modulators |
| EP4058434A1 (en) | 2019-11-12 | 2022-09-21 | Genzyme Corporation | 6-membered heteroarylaminosulfonamides for treating diseases and conditions mediated by deficient cftr activity |
| EP4225737A1 (en) * | 2020-10-07 | 2023-08-16 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| KR20230118123A (ko) | 2020-12-10 | 2023-08-10 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 치료 방법 |
| CN113480416B (zh) * | 2021-07-12 | 2023-03-21 | 重庆大学 | 一种芳基酮的制备方法 |
| KR20240168370A (ko) | 2022-03-30 | 2024-11-29 | 이시하라 산교 가부시끼가이샤 | 피리다지논계 화합물 또는 그의 염 및 그들을 함유하는 유해 생물 방제제 |
| CN114835655A (zh) * | 2022-04-14 | 2022-08-02 | 河南师范大学 | 一种合成光学活性三氟甲基丙烯酸酯类化合物的方法 |
| EP4611742A1 (en) | 2022-10-31 | 2025-09-10 | Sionna Therapeutics Inc. | Methods of treating cftr-mediated diseases or disorders |
| WO2025017207A1 (en) * | 2023-07-20 | 2025-01-23 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Inhibitors of smndc1 and their therapeutic use |
| WO2025076235A1 (en) | 2023-10-04 | 2025-04-10 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU654125B2 (en) * | 1991-03-07 | 1994-10-27 | Hisamitsu Pharmaceutical Co., Inc. | Novel diphenylthyazole derivative |
| AU689972B2 (en) * | 1994-11-29 | 1998-04-09 | Hisamitsu Pharmaceutical Co., Inc. | Antibacterial preparation or bactericide comprising 2-aminothiazole derivative and/or salt thereof |
| US20050004134A1 (en) * | 2001-11-08 | 2005-01-06 | Hideo Tsutsumi | Thiazole derivative and pharmaceutical use thereof |
| RU2006111093A (ru) * | 2003-09-06 | 2007-10-27 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Модуляторы атр-связывающих кассетных транспортеров |
| BR112013031485B1 (pt) * | 2011-06-10 | 2022-06-14 | Medimmune, Llc | Anticorpo monoclonal isolado ou fragmento de ligação a antígeno do mesmo, composição farmacêutica, usos e método in vitro para bloqueio ou prevenção da ligação de p. aeruginosa a células epiteliais |
| WO2016183173A1 (en) * | 2015-05-12 | 2016-11-17 | Avista Pharma Solutions | Antiparasitic compounds |
| US10138227B2 (en) * | 2016-06-03 | 2018-11-27 | Abbvie S.Á.R.L. | Heteroaryl substituted pyridines and methods of use |
| TW201811766A (zh) * | 2016-08-29 | 2018-04-01 | 瑞士商諾華公司 | N-(吡啶-2-基)吡啶-磺醯胺衍生物及其用於疾病治療之用途 |
| EP4611742A1 (en) * | 2022-10-31 | 2025-09-10 | Sionna Therapeutics Inc. | Methods of treating cftr-mediated diseases or disorders |
-
2020
- 2020-11-12 MX MX2022005809A patent/MX2022005809A/es unknown
- 2020-11-12 IL IL292966A patent/IL292966A/en unknown
- 2020-11-12 EP EP20820656.5A patent/EP4058439A1/en active Pending
- 2020-11-12 CN CN202080092755.2A patent/CN115003659B/zh active Active
- 2020-11-12 PH PH1/2022/551139A patent/PH12022551139A1/en unknown
- 2020-11-12 PE PE2022000772A patent/PE20221461A1/es unknown
- 2020-11-12 AU AU2020384279A patent/AU2020384279A1/en active Pending
- 2020-11-12 BR BR112022009185A patent/BR112022009185A2/pt unknown
- 2020-11-12 KR KR1020227019502A patent/KR20220115829A/ko active Pending
- 2020-11-12 WO PCT/US2020/060180 patent/WO2021097057A1/en not_active Ceased
- 2020-11-12 JP JP2022527081A patent/JP7721517B2/ja active Active
- 2020-11-12 CA CA3158057A patent/CA3158057A1/en active Pending
-
2022
- 2022-05-10 JO JOP/2022/0105A patent/JOP20220105A1/ar unknown
- 2022-05-11 US US17/742,169 patent/US20240002374A1/en active Pending
- 2022-05-12 CL CL2022001245A patent/CL2022001245A1/es unknown
- 2022-06-03 CO CONC2022/0007953A patent/CO2022007953A2/es unknown
- 2022-06-09 EC ECSENADI202246050A patent/ECSP22046050A/es unknown
-
2025
- 2025-07-30 JP JP2025126773A patent/JP2025160375A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2021097057A5 (https=) | ||
| RU2017126232A (ru) | Соединения, композиции и способы для повышения активности cftr | |
| JP2019513741A5 (https=) | ||
| HRP20210165T1 (hr) | Čvrsta disperzija amorfnog oblika (r)-1(2,2-difluorobenzo(d)(1,3)dioksol-5-il)-n-(1-(2,3-dihidroksipropil)-6-fluoro-2-(1-hidroksi-2-metilpropan-2-il)-1h-indol-5-il)-ciklopropankarboksamida | |
| RU2012129206A (ru) | Модуляторы атф-связывающих транспортеров | |
| JP2013513617A5 (https=) | ||
| RU2018116569A (ru) | Соединения, композиции и способы для модуляции cftr | |
| JP2013508414A5 (https=) | ||
| JP2013501787A5 (https=) | ||
| ME02799B (me) | Modulatori ATP-vezujućih kasetnih transportera | |
| HRP20160682T1 (hr) | Čvrsti oblici 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksiamido)-3-metilpiridin-2-il)benzojeve kiseline | |
| NZ598941A (en) | Isoquinoline modulators of ATP-Binding Cassette transporters | |
| US20130079367A1 (en) | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide | |
| JP2012521361A5 (https=) | ||
| JP2011516420A5 (https=) | ||
| NZ603044A (en) | Pharmaceutical compositions comprising cftr modulators and administrations thereof | |
| NZ746793A (en) | Silicone atoms containing ivacaftor analogues | |
| JP2011505338A5 (https=) | ||
| SI3091011T1 (en) | Modulators of ATP conveyor belt conveyors | |
| RU2012147272A (ru) | Фармацевтические композиции, включающие 3-(2, 2-дифторбензо[d][1, 3]диоксол-5-ил)циклопропанкарбоксамидо)-3-метилпиридин-2-ил)бензойную кислоту, и их введение | |
| NZ600772A (en) | Pyridyl derivatives as CFTR modulators | |
| ME02105B (me) | Modulatori atp-vezujucih kasetnih transportera | |
| JP2009522277A5 (https=) | ||
| JP2011513321A5 (https=) | ||
| US20250255859A1 (en) | Methods of treating cftr-mediated diseases or disorders |