JPWO2021001377A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021001377A5 JPWO2021001377A5 JP2021577986A JP2021577986A JPWO2021001377A5 JP WO2021001377 A5 JPWO2021001377 A5 JP WO2021001377A5 JP 2021577986 A JP2021577986 A JP 2021577986A JP 2021577986 A JP2021577986 A JP 2021577986A JP WO2021001377 A5 JPWO2021001377 A5 JP WO2021001377A5
- Authority
- JP
- Japan
- Prior art keywords
- cpla2e
- aav
- host cell
- cognitive impairment
- aav vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19382563.5 | 2019-07-02 | ||
EP19382563 | 2019-07-02 | ||
PCT/EP2020/068414 WO2021001377A1 (fr) | 2019-07-02 | 2020-06-30 | Agents induisant la cpla2e et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022544740A JP2022544740A (ja) | 2022-10-21 |
JPWO2021001377A5 true JPWO2021001377A5 (fr) | 2023-07-10 |
Family
ID=67402895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021577986A Pending JP2022544740A (ja) | 2019-07-02 | 2020-06-30 | cPLA2e誘導剤及びその使用 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20220233722A1 (fr) |
EP (1) | EP3993871A1 (fr) |
JP (1) | JP2022544740A (fr) |
CN (1) | CN114222818A (fr) |
AU (1) | AU2020299718A1 (fr) |
CA (1) | CA3145446A1 (fr) |
WO (1) | WO2021001377A1 (fr) |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
WO1992001070A1 (fr) | 1990-07-09 | 1992-01-23 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Conditionnement a haute efficacite de virus adeno-associe mutant utilisant la suppression d'ambre |
US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
DE69233013T2 (de) | 1991-08-20 | 2004-03-04 | The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
US5478857A (en) * | 1993-12-23 | 1995-12-26 | Eli Lilly And Company | Use of PLA2 inhibitors as treatment for alzheimer's disease |
FR2808803B1 (fr) | 2000-05-11 | 2004-12-10 | Agronomique Inst Nat Rech | Cellules es modifiees et gene specifique de cellules es |
FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
EP1528101A1 (fr) | 2003-11-03 | 2005-05-04 | ProBioGen AG | Lignées cellulaires aviaires immortalisées pour la production de virus |
FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
EP1985305A1 (fr) | 2007-04-24 | 2008-10-29 | Vivalis | Lignées de cellules souches dérivées d'embryons de canard pour la fabrication de vaccins viraux |
EP1995309A1 (fr) | 2007-05-21 | 2008-11-26 | Vivalis | Production de protéine recombinante dans des cellules aviaires EBx |
JP2011526916A (ja) * | 2008-06-30 | 2011-10-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 全身性紅斑性狼瘡を同定および処置するための診断標的および治療標的としてのリソソームホスホリパーゼa2(lpla2)活性 |
AU2012255913A1 (en) | 2011-05-17 | 2013-11-21 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof for non-human vertebrates |
US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
WO2014164253A1 (fr) | 2013-03-09 | 2014-10-09 | Moderna Therapeutics, Inc. | Régions non traduites hétérologues pour arnm |
US20150167017A1 (en) | 2013-12-13 | 2015-06-18 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
US20170204152A1 (en) | 2014-07-16 | 2017-07-20 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
JP2017523777A (ja) | 2014-07-17 | 2017-08-24 | モデルナティエックス インコーポレイテッドModernaTX,Inc. | ポリヌクレオチドの末端修飾 |
WO2016014846A1 (fr) | 2014-07-23 | 2016-01-28 | Moderna Therapeutics, Inc. | Polynucléotides modifiés destinés à la production d'anticorps intracellulaires |
-
2020
- 2020-06-30 AU AU2020299718A patent/AU2020299718A1/en active Pending
- 2020-06-30 EP EP20735571.0A patent/EP3993871A1/fr active Pending
- 2020-06-30 US US17/624,178 patent/US20220233722A1/en active Pending
- 2020-06-30 CN CN202080049050.2A patent/CN114222818A/zh active Pending
- 2020-06-30 JP JP2021577986A patent/JP2022544740A/ja active Pending
- 2020-06-30 WO PCT/EP2020/068414 patent/WO2021001377A1/fr unknown
- 2020-06-30 CA CA3145446A patent/CA3145446A1/fr active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11866462B2 (en) | Recombinant adeno-associated viral vectors | |
US11572637B2 (en) | Methods of viral neutralizing antibody epitope mapping | |
US20210355481A1 (en) | Aav capsid proteins for nucleic acid transfer | |
MIZUKAMI et al. | Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein | |
CA2985945C (fr) | Capside | |
Vandenberghe et al. | Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing | |
Mori et al. | Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein | |
US7220577B2 (en) | Modified AAV | |
JP2020048586A (ja) | 空キャプシドを実質的に含まない組換えaavビリオン調製物を生成するための方法 | |
US7037713B2 (en) | High-efficiency wild-type-free AAV helper functions | |
WO2022067935A1 (fr) | Mutant de virus adéno-associé et son application | |
AU2002352261A1 (en) | A library of modified structural genes or capsid modified particles useful for the identification of viral clones with desired cell tropism | |
JP2023171525A (ja) | Aavキメラ | |
JP4472182B2 (ja) | 放出された組換えaavベクターの高力価のヘルパーを含まない調製物を生成するための方法 | |
TW202246516A (zh) | 病毒蛋白之控制表現 | |
CN112899276B (zh) | 迷你启动子pHSP90AA1及其应用 | |
JPWO2021001377A5 (fr) | ||
CZ20996A3 (en) | Epstein-barr virus sequences encoding diagnostically relevant viral capside antigen, expression clones obtained by polymerase chain reaction and the use of such recombinant antigen in diagnostic tests | |
KR100535325B1 (ko) | Aav 유전자 전달체 제조용 헬퍼 플라스미드 | |
Zhou et al. | 90. Evaluation of Novel Gene Transfer Vectors Derived from Infectious Molecular Clones of Primate AAVs | |
Faust et al. | 91. Universal purification of AAV serotypes 1-5 modified to contain a heparin binding epitope | |
Bhrigu | Replication of adeno-associated virus in murine fibroblasts with mouse adenovirus provided helper functions | |
JPWO2021011034A5 (fr) |