JPWO2020242984A5 - - Google Patents
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- Publication number
- JPWO2020242984A5 JPWO2020242984A5 JP2021569402A JP2021569402A JPWO2020242984A5 JP WO2020242984 A5 JPWO2020242984 A5 JP WO2020242984A5 JP 2021569402 A JP2021569402 A JP 2021569402A JP 2021569402 A JP2021569402 A JP 2021569402A JP WO2020242984 A5 JPWO2020242984 A5 JP WO2020242984A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- acid sequence
- seq
- amino acid
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962852791P | 2019-05-24 | 2019-05-24 | |
| US62/852,791 | 2019-05-24 | ||
| PCT/US2020/034328 WO2020242984A1 (en) | 2019-05-24 | 2020-05-22 | Modified viral particles and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022533438A JP2022533438A (ja) | 2022-07-22 |
| JPWO2020242984A5 true JPWO2020242984A5 (ko) | 2023-05-30 |
Family
ID=71094822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569402A Pending JP2022533438A (ja) | 2019-05-24 | 2020-05-22 | 改変ウイルス粒子およびその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20220241430A1 (ko) |
| EP (1) | EP3976631A1 (ko) |
| JP (1) | JP2022533438A (ko) |
| KR (1) | KR20220011664A (ko) |
| CN (2) | CN113874386A (ko) |
| AR (2) | AR118997A1 (ko) |
| AU (1) | AU2020283537A1 (ko) |
| BR (1) | BR112021023692A2 (ko) |
| CA (1) | CA3140386A1 (ko) |
| CL (2) | CL2021003096A1 (ko) |
| CO (1) | CO2021017692A2 (ko) |
| IL (1) | IL288233A (ko) |
| MA (1) | MA56035A (ko) |
| MX (1) | MX2021014338A (ko) |
| PE (1) | PE20212357A1 (ko) |
| SG (1) | SG11202112917PA (ko) |
| TW (1) | TW202110869A (ko) |
| WO (1) | WO2020242984A1 (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021023692A2 (pt) * | 2019-05-24 | 2022-01-04 | Regeneron Pharma | Partícula viral de vírus adeno-associado recombinante, proteína de capsídeo de vírus adeno-associado, molécula de ácido nucleico, célula empacotadora, métodos de produção de uma partícula viral e de distribuição de um nucleotídeo, e, composição farmacêutica |
| WO2022187377A1 (en) * | 2021-03-02 | 2022-09-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Adeno-associated viruses and methods and materials for making and using adeno-associated viruses |
| EP4314021A1 (en) * | 2021-04-30 | 2024-02-07 | Duke University | Compositions comprising adeno-associated virus chimera capsid proteins and methods of using the same |
| US20240294578A1 (en) * | 2021-06-23 | 2024-09-05 | Dyno Therapeutics, Inc. | Capsid variants and methods of using the same |
| WO2023220603A1 (en) | 2022-05-09 | 2023-11-16 | Regeneron Pharmaceuticals, Inc. | Vectors and methods for in vivo antibody production |
| WO2023240124A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997005266A1 (en) | 1995-07-25 | 1997-02-13 | Introgene B.V. | Methods and means for targeted gene delivery |
| AU4645697A (en) | 1996-09-11 | 1998-04-02 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Aav4 vector and uses thereof |
| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| CA2745131C (en) | 1998-05-28 | 2016-08-09 | John A. Chiorini | Aav5 vector and uses thereof |
| JP4573437B2 (ja) | 1998-11-05 | 2010-11-04 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | アデノ随伴ウイルス血清型１核酸配列、ベクターおよび同一物を含有する宿主細胞 |
| PL222683B1 (pl) * | 2001-11-13 | 2016-08-31 | Univ Pennsylvania | Rekombinowane wirusy stowarzyszone z adenowirusem (AAV), sposoby ich wytwarzania, pakująca komórka gospodarza, kompozycja zawierająca wirus, zastosowanie wirusa, wyizolowane wirusy AAV, białka,sztuczne białka kapsydu, cząsteczki, komórki gospodarza, sposoby dostarczania transgenu, sposób identyfikacji serotypu, zestaw diagnostyczny, sposób izolacji nowych wirusów, rekombinowana komórka |
| DK2158211T3 (en) | 2007-05-31 | 2016-12-05 | Medigene Ag | Mutated structural protein of a parvovirus |
| ES2595376T3 (es) | 2009-12-10 | 2016-12-29 | Regeneron Pharmaceuticals, Inc. | Ratones que producen anticuerpos de cadena pesada |
| GB201002362D0 (en) | 2010-02-11 | 2010-03-31 | Isis Innovation | Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds |
| EP3117005B1 (en) * | 2014-03-10 | 2024-07-03 | uniQure IP B.V. | Further improved aav vectors produced in insect cells |
| KR20210088756A (ko) | 2014-03-21 | 2021-07-14 | 리제너론 파마슈티칼스 인코포레이티드 | 단일 도메인 결합 단백질을 생산하는 비-인간 동물 |
| WO2015191508A1 (en) * | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| KR20240149451A (ko) | 2017-06-27 | 2024-10-14 | 리제너론 파마슈티칼스 인코포레이티드 | 유전 물질을 인간 세포 내로 표적화하여 도입하기 위한 향성-변형 재조합 바이러스 벡터 및 이의 용도 |
| HRP20230538T1 (hr) * | 2017-06-27 | 2023-08-04 | Regeneron Pharmaceuticals, Inc. | Rekombinantne virusne čestice s modificiranim tropizmom i njihove upotrebe za ciljano uvođenje genetičkog materijala u humane stanice |
| BR112021023692A2 (pt) * | 2019-05-24 | 2022-01-04 | Regeneron Pharma | Partícula viral de vírus adeno-associado recombinante, proteína de capsídeo de vírus adeno-associado, molécula de ácido nucleico, célula empacotadora, métodos de produção de uma partícula viral e de distribuição de um nucleotídeo, e, composição farmacêutica |
-
2020
- 2020-05-22 BR BR112021023692A patent/BR112021023692A2/pt unknown
- 2020-05-22 JP JP2021569402A patent/JP2022533438A/ja active Pending
- 2020-05-22 WO PCT/US2020/034328 patent/WO2020242984A1/en unknown
- 2020-05-22 TW TW109117155A patent/TW202110869A/zh unknown
- 2020-05-22 MA MA056035A patent/MA56035A/fr unknown
- 2020-05-22 CA CA3140386A patent/CA3140386A1/en active Pending
- 2020-05-22 EP EP20733099.4A patent/EP3976631A1/en active Pending
- 2020-05-22 CN CN202080038612.3A patent/CN113874386A/zh active Pending
- 2020-05-22 US US17/612,669 patent/US20220241430A1/en active Pending
- 2020-05-22 PE PE2021001934A patent/PE20212357A1/es unknown
- 2020-05-22 CN CN202210622571.3A patent/CN114989267A/zh active Pending
- 2020-05-22 AR ARP200101465A patent/AR118997A1/es unknown
- 2020-05-22 MX MX2021014338A patent/MX2021014338A/es unknown
- 2020-05-22 KR KR1020217041074A patent/KR20220011664A/ko active Search and Examination
- 2020-05-22 AU AU2020283537A patent/AU2020283537A1/en active Pending
- 2020-05-22 SG SG11202112917PA patent/SG11202112917PA/en unknown
-
2021
- 2021-11-18 IL IL288233A patent/IL288233A/en unknown
- 2021-11-19 AR ARP210103220A patent/AR124119A2/es unknown
- 2021-11-23 CL CL2021003096A patent/CL2021003096A1/es unknown
- 2021-12-22 CO CONC2021/0017692A patent/CO2021017692A2/es unknown
-
2023
- 2023-03-03 CL CL2023000629A patent/CL2023000629A1/es unknown
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