JPWO2020185867A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020185867A5 JPWO2020185867A5 JP2021554697A JP2021554697A JPWO2020185867A5 JP WO2020185867 A5 JPWO2020185867 A5 JP WO2020185867A5 JP 2021554697 A JP2021554697 A JP 2021554697A JP 2021554697 A JP2021554697 A JP 2021554697A JP WO2020185867 A5 JPWO2020185867 A5 JP WO2020185867A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- guided endonuclease
- target site
- modifications
- donor dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024116841A JP2024133347A (ja) | 2019-03-11 | 2024-07-22 | Ｒｎａ誘導型エンドヌクレアーゼを使用したｄｎａ構築物の組み込みプロセスの向上 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962816836P | 2019-03-11 | 2019-03-11 | |
| US62/816,836 | 2019-03-11 | ||
| US201962901735P | 2019-09-17 | 2019-09-17 | |
| US62/901,735 | 2019-09-17 | ||
| PCT/US2020/022056 WO2020185867A1 (en) | 2019-03-11 | 2020-03-11 | Improved process for integration of dna constructs using rna-guided endonucleases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024116841A Division JP2024133347A (ja) | 2019-03-11 | 2024-07-22 | Ｒｎａ誘導型エンドヌクレアーゼを使用したｄｎａ構築物の組み込みプロセスの向上 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022524435A JP2022524435A (ja) | 2022-05-02 |
| JP2022524435A5 JP2022524435A5 (https=) | 2023-03-15 |
| JPWO2020185867A5 true JPWO2020185867A5 (https=) | 2023-03-15 |
Family
ID=70190148
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021554697A Pending JP2022524435A (ja) | 2019-03-11 | 2020-03-11 | Ｒｎａ誘導型エンドヌクレアーゼを使用したｄｎａ構築物の組み込みプロセスの向上 |
| JP2024116841A Pending JP2024133347A (ja) | 2019-03-11 | 2024-07-22 | Ｒｎａ誘導型エンドヌクレアーゼを使用したｄｎａ構築物の組み込みプロセスの向上 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024116841A Pending JP2024133347A (ja) | 2019-03-11 | 2024-07-22 | Ｒｎａ誘導型エンドヌクレアーゼを使用したｄｎａ構築物の組み込みプロセスの向上 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220145333A1 (https=) |
| EP (1) | EP3938510A1 (https=) |
| JP (2) | JP2022524435A (https=) |
| KR (1) | KR20210149734A (https=) |
| CN (1) | CN113825834A (https=) |
| AU (1) | AU2020239050A1 (https=) |
| CA (1) | CA3133226A1 (https=) |
| IL (1) | IL286244A (https=) |
| MX (1) | MX2021010938A (https=) |
| SG (1) | SG11202109972QA (https=) |
| WO (1) | WO2020185867A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4139345A1 (en) | 2020-04-24 | 2023-03-01 | Sorrento Therapeutics, Inc. | Memory dimeric antigen receptors |
| WO2022015956A1 (en) | 2020-07-15 | 2022-01-20 | Sorrento Therapeutics, Inc. | Improved process for dna integration using rna-guided endonucleases |
| WO2022061115A1 (en) * | 2020-09-18 | 2022-03-24 | Vor Biopharma Inc. | Compositions and methods for cd7 modification |
| BR112023018948A2 (pt) * | 2021-03-19 | 2023-10-17 | Metagenomi Inc | Edição multiplex com enzimas cas |
| JP2024513087A (ja) * | 2021-04-07 | 2024-03-21 | アストラゼネカ・アクチエボラーグ | 部位特異的改変のための組成物及び方法 |
| EP4370676A2 (en) * | 2021-06-18 | 2024-05-22 | Artisan Development Labs, Inc. | Compositions and methods for targeting, editing or modifying human genes |
| WO2023097236A1 (en) * | 2021-11-24 | 2023-06-01 | The Rockefeller University | Compositions and methods for generating immunoglobulin knock-in mice |
| CN115851591A (zh) * | 2022-11-30 | 2023-03-28 | 山东博群生物技术有限公司 | 细胞因子刺激剂及诱导淋巴细胞产生细胞因子的方法 |
| WO2026020171A2 (en) | 2024-07-19 | 2026-01-22 | Aera Therapeutics, Inc. | Chimeric antigen receptor constructs |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5489677A (en) | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US6555674B2 (en) | 2000-08-09 | 2003-04-29 | Nsgene A/S | JeT promoter |
| EP2281050B1 (en) * | 2008-04-14 | 2014-04-02 | Sangamo BioSciences, Inc. | Linear donor constructs for targeted integration |
| EP3241902B1 (en) | 2012-05-25 | 2018-02-28 | The Regents of The University of California | Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| AU2014361834B2 (en) | 2013-12-12 | 2020-10-22 | Massachusetts Institute Of Technology | CRISPR-Cas systems and methods for altering expression of gene products, structural information and inducible modular Cas enzymes |
| WO2016057951A2 (en) * | 2014-10-09 | 2016-04-14 | Life Technologies Corporation | Crispr oligonucleotides and gene editing |
| AU2016261358B2 (en) * | 2015-05-11 | 2021-09-16 | Editas Medicine, Inc. | Optimized CRISPR/Cas9 systems and methods for gene editing in stem cells |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| AU2016338785B2 (en) * | 2015-10-12 | 2022-07-14 | E. I. Du Pont De Nemours And Company | Protected DNA templates for gene modification and increased homologous recombination in cells and methods of use |
| CA3038960A1 (en) | 2016-09-30 | 2018-04-05 | The Regents Of The University Of California | Rna-guided nucleic acid modifying enzymes and methods of use thereof |
| WO2018175636A2 (en) * | 2017-03-22 | 2018-09-27 | Novartis Ag | Compositions and methods for immunooncology |
| CA3067382A1 (en) * | 2017-06-15 | 2018-12-20 | The Regents Of The University Of California | Targeted non-viral dna insertions |
| CA3071683A1 (en) * | 2017-08-08 | 2019-02-14 | Sangamo Therapeutics, Inc. | Chimeric antigen receptor mediated cell targeting |
| SG11202008568WA (en) | 2018-03-09 | 2020-10-29 | Sorrento Therapeutics Inc | Dimeric antigen receptors (dar) |
-
2020
- 2020-03-11 US US17/438,039 patent/US20220145333A1/en not_active Abandoned
- 2020-03-11 SG SG11202109972Q patent/SG11202109972QA/en unknown
- 2020-03-11 WO PCT/US2020/022056 patent/WO2020185867A1/en not_active Ceased
- 2020-03-11 AU AU2020239050A patent/AU2020239050A1/en not_active Abandoned
- 2020-03-11 KR KR1020217032629A patent/KR20210149734A/ko not_active Withdrawn
- 2020-03-11 CA CA3133226A patent/CA3133226A1/en active Pending
- 2020-03-11 JP JP2021554697A patent/JP2022524435A/ja active Pending
- 2020-03-11 MX MX2021010938A patent/MX2021010938A/es unknown
- 2020-03-11 CN CN202080035087.XA patent/CN113825834A/zh active Pending
- 2020-03-11 EP EP20717424.4A patent/EP3938510A1/en not_active Withdrawn
-
2021
- 2021-09-09 IL IL286244A patent/IL286244A/en unknown
-
2024
- 2024-07-22 JP JP2024116841A patent/JP2024133347A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12398393B2 (en) | RNA-editing oligonucleotides for the treatment of usher syndrome | |
| JP2024174943A5 (https=) | ||
| US7053195B1 (en) | Locked nucleic acid containing heteropolymers and related methods | |
| JP6997623B2 (ja) | オリゴヌクレオチドを利用して細胞内の核酸を編集するための組成物および方法 | |
| JP6872560B2 (ja) | プログラム可能ヌクレアーゼのあるゲノム編集及びプログラム可能ヌクレアーゼのないゲノム編集のための改善された方法 | |
| US11884915B2 (en) | Guide RNAs with chemical modification for prime editing | |
| JP4063326B2 (ja) | 非天然ヌクレオチドを有するキメラ突然変異性ベクター | |
| US6211351B1 (en) | Chimeric mutational vectors | |
| JP2018533959A5 (https=) | ||
| KR20180081600A (ko) | 티틴-기반 근증 및 다른 티틴성병증의 치료를 위한 물질 및 방법 | |
| EP3126495A1 (en) | Crispr/cas-related methods and compositions for treating primary open angle glaucoma | |
| EP3129485A2 (en) | Crispr/cas-related methods and compositions for treating cystic fibrosis | |
| EP3277816A1 (en) | Crispr/cas-related methods and compositions for treating duchenne muscular dystrophy and becker muscular dystrophy | |
| CA3025523A1 (en) | Peptides and nanoparticles for intracellular delivery of genome-editing molecules | |
| US12275951B2 (en) | Engineered guide RNA and uses thereof | |
| JP2024107295A5 (https=) | ||
| CN114981445B (zh) | 修饰的双链供体模板 | |
| JPWO2020185867A5 (https=) | ||
| JP2024533448A (ja) | 化学修飾を有するガイドｒｎａを使用する方法 | |
| CN117377762A (zh) | 新型CRISPR gRNA | |
| JPWO2020176740A5 (https=) | ||
| JP2025509392A (ja) | 改変型ｃｒｉｓｐｒベースの遺伝子編集システムおよび使用方法 | |
| Dysko et al. | Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides | |
| HK40116631A (zh) | 修饰的基於crispr的基因编辑系统及其使用方法 | |
| CN121472227A (zh) | 一种cd34+细胞基因编辑复合物及其应用 |