CN113825834A - 使用rna引导的核酸内切酶进行dna构建体整合的改进工艺 - Google Patents

使用rna引导的核酸内切酶进行dna构建体整合的改进工艺 Download PDF

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CN113825834A
CN113825834A CN202080035087.XA CN202080035087A CN113825834A CN 113825834 A CN113825834 A CN 113825834A CN 202080035087 A CN202080035087 A CN 202080035087A CN 113825834 A CN113825834 A CN 113825834A
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nucleotides
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cells
donor dna
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丁蓓蓓
郭文忠
张延良
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Sorento Pharmaceutical Co Ltd
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CN202080035087.XA 2019-03-11 2020-03-11 使用rna引导的核酸内切酶进行dna构建体整合的改进工艺 Pending CN113825834A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962816836P 2019-03-11 2019-03-11
US62/816,836 2019-03-11
US201962901735P 2019-09-17 2019-09-17
US62/901,735 2019-09-17
PCT/US2020/022056 WO2020185867A1 (en) 2019-03-11 2020-03-11 Improved process for integration of dna constructs using rna-guided endonucleases

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US (1) US20220145333A1 (https=)
EP (1) EP3938510A1 (https=)
JP (2) JP2022524435A (https=)
KR (1) KR20210149734A (https=)
CN (1) CN113825834A (https=)
AU (1) AU2020239050A1 (https=)
CA (1) CA3133226A1 (https=)
IL (1) IL286244A (https=)
MX (1) MX2021010938A (https=)
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CN115851591A (zh) * 2022-11-30 2023-03-28 山东博群生物技术有限公司 细胞因子刺激剂及诱导淋巴细胞产生细胞因子的方法

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WO2022015956A1 (en) 2020-07-15 2022-01-20 Sorrento Therapeutics, Inc. Improved process for dna integration using rna-guided endonucleases
WO2022061115A1 (en) * 2020-09-18 2022-03-24 Vor Biopharma Inc. Compositions and methods for cd7 modification
BR112023018948A2 (pt) * 2021-03-19 2023-10-17 Metagenomi Inc Edição multiplex com enzimas cas
JP2024513087A (ja) * 2021-04-07 2024-03-21 アストラゼネカ・アクチエボラーグ 部位特異的改変のための組成物及び方法
EP4370676A2 (en) * 2021-06-18 2024-05-22 Artisan Development Labs, Inc. Compositions and methods for targeting, editing or modifying human genes
WO2023097236A1 (en) * 2021-11-24 2023-06-01 The Rockefeller University Compositions and methods for generating immunoglobulin knock-in mice
WO2026020171A2 (en) 2024-07-19 2026-01-22 Aera Therapeutics, Inc. Chimeric antigen receptor constructs

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EP3938510A1 (en) 2022-01-19
WO2020185867A1 (en) 2020-09-17
CA3133226A1 (en) 2020-09-17
JP2022524435A (ja) 2022-05-02
KR20210149734A (ko) 2021-12-09
JP2024133347A (ja) 2024-10-01
AU2020239050A1 (en) 2021-11-04
MX2021010938A (es) 2022-01-06
US20220145333A1 (en) 2022-05-12
IL286244A (en) 2021-10-31

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