JPWO2020184700A5 - - Google Patents

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Publication number
JPWO2020184700A5
JPWO2020184700A5 JP2021505155A JP2021505155A JPWO2020184700A5 JP WO2020184700 A5 JPWO2020184700 A5 JP WO2020184700A5 JP 2021505155 A JP2021505155 A JP 2021505155A JP 2021505155 A JP2021505155 A JP 2021505155A JP WO2020184700 A5 JPWO2020184700 A5 JP WO2020184700A5
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JP
Japan
Prior art keywords
nucleic acid
acid complex
oligonucleotide
strand
fibrosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021505155A
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English (en)
Japanese (ja)
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JPWO2020184700A1 (https=
JP7530106B2 (ja
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Priority claimed from PCT/JP2020/011018 external-priority patent/WO2020184700A1/ja
Publication of JPWO2020184700A1 publication Critical patent/JPWO2020184700A1/ja
Publication of JPWO2020184700A5 publication Critical patent/JPWO2020184700A5/ja
Application granted granted Critical
Publication of JP7530106B2 publication Critical patent/JP7530106B2/ja
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JP2021505155A 2019-03-14 2020-03-13 Ｉｈｈ発現を調節するための核酸複合体 Active JP7530106B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019047703 2019-03-14
JP2019047703 2019-03-14
PCT/JP2020/011018 WO2020184700A1 (ja) 2019-03-14 2020-03-13 Ｉｈｈ発現を調節するための核酸複合体

Publications (3)

Publication Number Publication Date
JPWO2020184700A1 JPWO2020184700A1 (https=) 2020-09-17
JPWO2020184700A5 true JPWO2020184700A5 (https=) 2023-02-27
JP7530106B2 JP7530106B2 (ja) 2024-08-07

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JP2021505155A Active JP7530106B2 (ja) 2019-03-14 2020-03-13 Ｉｈｈ発現を調節するための核酸複合体

Country Status (4)

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US (1) US12492399B2 (https=)
EP (1) EP3981431A4 (https=)
JP (1) JP7530106B2 (https=)
WO (1) WO2020184700A1 (https=)

Family Cites Families (28)

* Cited by examiner, † Cited by third party
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JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ／エス オリゴヌクレオチド類似体
US7803781B2 (en) 2003-02-28 2010-09-28 Isis Pharmaceuticals, Inc. Modulation of growth hormone receptor expression and insulin-like growth factor expression
EP1661905B9 (en) 2003-08-28 2012-12-19 IMANISHI, Takeshi Novel artificial nucleic acids of n-o bond crosslinkage type
WO2005097207A2 (en) * 2004-03-26 2005-10-20 Curis, Inc. Rna interference modulators of hedgehog signaling and uses thereof
US8410246B2 (en) * 2004-06-17 2013-04-02 Thrasos, Inc. TDF-related compounds and analogs thereof
JP2009536222A (ja) 2006-05-05 2009-10-08 アイシス ファーマシューティカルズ， インコーポレーテッド Ｐｃｓｋ９の発現を調節するための化合物および方法
WO2008029619A1 (fr) 2006-09-07 2008-03-13 Daiichi Sankyo Company, Limited Oligonucléotide antisens ena ayant une action spécifique de la séquence
CA2666191C (en) 2006-10-09 2017-07-11 Santaris Pharma A/S Rna antagonist compounds for the modulation of pcsk9
ES2526295T5 (es) 2006-10-18 2021-05-04 Ionis Pharmaceuticals Inc Compuestos antisentido
WO2009138516A1 (en) * 2008-05-16 2009-11-19 Galderma Research & Development Therapy regimen for treating acne related diseases
NZ601660A (en) * 2008-08-25 2014-05-30 Excaliard Pharmaceuticals Inc Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
US20140154783A1 (en) 2009-07-06 2014-06-05 Alnylam Pharmaceuticals, Inc. Bioprocessing
EP2295543A1 (en) * 2009-09-11 2011-03-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the preparation of an influenza virus
US20110183948A1 (en) 2010-01-15 2011-07-28 Infinity Pharmaceuticals, Inc. Treatment of fibrotic conditions using hedgehog inhibitors
KR101463182B1 (ko) * 2011-01-13 2014-11-21 연세대학교 산학협력단 췌장암 암줄기세포 특성을 이용한 췌장암 신규 바이오마커 및 그의 용도
US20120252870A1 (en) * 2011-02-19 2012-10-04 Rhode Island Hospital Indian Hedgehog (Ihh) as a Marker to Predict Osteoarthritis (OA) and Methods for the Prevention and Treatment of OA
EP3460064B8 (en) 2011-04-03 2024-03-20 The General Hospital Corporation d/b/a Massachusetts General Hospital Efficient protein expression in vivo using modified rna (mod-rna)
BR112013025917A2 (pt) * 2011-04-08 2016-12-20 Omeros Corp uso de um anticorpo masp-2 ou fragmento do mesmo que inibe ativação de complemento dependente de masp-2
WO2013043817A1 (en) 2011-09-20 2013-03-28 Isis Phamaceuticals, Inc. Antisense modulation of gcgr expression
KR20140128257A (ko) * 2013-04-26 2014-11-05 주식회사 에이앤알티 표적 단백질 스크리닝을 위한 수용성 수용체 라이브러리 및 이를 이용한 표적 단백질 스크리닝 방법
AU2016243583B2 (en) * 2015-03-27 2022-03-10 President And Fellows Of Harvard College Modified T cells and methods of making and using the same
WO2017131124A1 (ja) 2016-01-26 2017-08-03 日産化学工業株式会社 一本鎖オリゴヌクレオチド
EP3445385A4 (en) 2016-04-18 2019-11-20 The Trustees of Columbia University in the City of New York THERAPEUTIC GOALS INVOLVED IN THE PROGRESSION OF NON-ALCOHOLIC STEATOHEPATITIS (NASH)
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BR112020001430A2 (pt) * 2017-07-26 2020-07-28 Nissan Chemical Corporation oligonucleotídeo de fita simples
JP2019047703A (ja) 2017-09-07 2019-03-22 イビデン株式会社 モータ用コイル

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