JPWO2020184700A5 - - Google Patents
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- Publication number
- JPWO2020184700A5 JPWO2020184700A5 JP2021505155A JP2021505155A JPWO2020184700A5 JP WO2020184700 A5 JPWO2020184700 A5 JP WO2020184700A5 JP 2021505155 A JP2021505155 A JP 2021505155A JP 2021505155 A JP2021505155 A JP 2021505155A JP WO2020184700 A5 JPWO2020184700 A5 JP WO2020184700A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid complex
- oligonucleotide
- strand
- fibrosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019047703 | 2019-03-14 | ||
| JP2019047703 | 2019-03-14 | ||
| PCT/JP2020/011018 WO2020184700A1 (ja) | 2019-03-14 | 2020-03-13 | Ihh発現を調節するための核酸複合体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020184700A1 JPWO2020184700A1 (https=) | 2020-09-17 |
| JPWO2020184700A5 true JPWO2020184700A5 (https=) | 2023-02-27 |
| JP7530106B2 JP7530106B2 (ja) | 2024-08-07 |
Family
ID=72427147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505155A Active JP7530106B2 (ja) | 2019-03-14 | 2020-03-13 | Ihh発現を調節するための核酸複合体 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US12492399B2 (https=) |
| EP (1) | EP3981431A4 (https=) |
| JP (1) | JP7530106B2 (https=) |
| WO (1) | WO2020184700A1 (https=) |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3781879B2 (ja) | 1996-11-18 | 2006-05-31 | 武 今西 | 新規ヌクレオチド類縁体 |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| AU9063398A (en) | 1997-09-12 | 1999-04-05 | Exiqon A/S | Oligonucleotide analogues |
| US7803781B2 (en) | 2003-02-28 | 2010-09-28 | Isis Pharmaceuticals, Inc. | Modulation of growth hormone receptor expression and insulin-like growth factor expression |
| EP1661905B9 (en) | 2003-08-28 | 2012-12-19 | IMANISHI, Takeshi | Novel artificial nucleic acids of n-o bond crosslinkage type |
| DK1730280T3 (en) * | 2004-03-26 | 2019-02-04 | Curis Inc | RNA interference modulators for hedgehog signaling and applications thereof |
| JP4971149B2 (ja) * | 2004-06-17 | 2012-07-11 | スラソス セラピューティックス インコーポレーテッド | Tdf関連化合物およびその類似体 |
| EP2023940B1 (en) | 2006-05-05 | 2011-06-22 | Isis Pharmaceuticals, Inc. | Compounds and methods for modulating expression of sglt2 |
| WO2008029619A1 (fr) | 2006-09-07 | 2008-03-13 | Daiichi Sankyo Company, Limited | Oligonucléotide antisens ena ayant une action spécifique de la séquence |
| ES2603379T3 (es) | 2006-10-09 | 2017-02-27 | Roche Innovation Center Copenhagen A/S | Compuestos antagonistas de ARN para la modulación de PCSK9 |
| WO2008049085A1 (en) | 2006-10-18 | 2008-04-24 | Isis Pharmaceuticals, Inc. | Antisense compounds |
| WO2009138516A1 (en) * | 2008-05-16 | 2009-11-19 | Galderma Research & Development | Therapy regimen for treating acne related diseases |
| NZ601660A (en) | 2008-08-25 | 2014-05-30 | Excaliard Pharmaceuticals Inc | Antisense oligonucleotides directed against connective tissue growth factor and uses thereof |
| WO2011005765A1 (en) | 2009-07-06 | 2011-01-13 | Alnylam Pharmaceuticals, Inc. | Bioprocessing |
| EP2295543A1 (en) * | 2009-09-11 | 2011-03-16 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for the preparation of an influenza virus |
| US20110183948A1 (en) | 2010-01-15 | 2011-07-28 | Infinity Pharmaceuticals, Inc. | Treatment of fibrotic conditions using hedgehog inhibitors |
| WO2012096545A2 (ko) * | 2011-01-13 | 2012-07-19 | 연세대학교 산학협력단 | 췌장암 암줄기세포 특성을 이용한 췌장암 신규 바이오마커 및 그의 용도 |
| US20120252870A1 (en) * | 2011-02-19 | 2012-10-04 | Rhode Island Hospital | Indian Hedgehog (Ihh) as a Marker to Predict Osteoarthritis (OA) and Methods for the Prevention and Treatment of OA |
| EP2694660B1 (en) * | 2011-04-03 | 2018-08-08 | The General Hospital Corporation | Efficient protein expression in vivo using modified rna (mod-rna) |
| KR101870915B1 (ko) * | 2011-04-08 | 2018-06-25 | 유니버시티 오브 레스터 | Masp-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법 |
| ES2796556T3 (es) | 2011-09-20 | 2020-11-27 | Ionis Pharmaceuticals Inc | Modulación antisentido de la expresión de GCGR |
| KR20140128257A (ko) * | 2013-04-26 | 2014-11-05 | 주식회사 에이앤알티 | 표적 단백질 스크리닝을 위한 수용성 수용체 라이브러리 및 이를 이용한 표적 단백질 스크리닝 방법 |
| KR20260048600A (ko) * | 2015-03-27 | 2026-04-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 변형된 t 세포 및 이의 제조 및 사용 방법 |
| WO2017131124A1 (ja) | 2016-01-26 | 2017-08-03 | 日産化学工業株式会社 | 一本鎖オリゴヌクレオチド |
| WO2017184586A1 (en) * | 2016-04-18 | 2017-10-26 | The Trustees Of Columbia University In The City Of New York | Therapeutic targets involved in the progression of nonalcoholic steatohepatitis (nash) |
| CN108728440A (zh) * | 2017-04-25 | 2018-11-02 | 上海吉倍生物技术有限公司 | Ctla-4基因的用途及相关药物 |
| AU2018307294B2 (en) | 2017-07-26 | 2025-04-17 | Nissan Chemical Corporation | Single-stranded oligonucleotide |
| JP2019047703A (ja) | 2017-09-07 | 2019-03-22 | イビデン株式会社 | モータ用コイル |
-
2020
- 2020-03-13 JP JP2021505155A patent/JP7530106B2/ja active Active
- 2020-03-13 US US17/437,692 patent/US12492399B2/en active Active
- 2020-03-13 EP EP20770166.5A patent/EP3981431A4/en active Pending
- 2020-03-13 WO PCT/JP2020/011018 patent/WO2020184700A1/ja not_active Ceased
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