JPWO2020154535A5 - - Google Patents
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- Publication number
- JPWO2020154535A5 JPWO2020154535A5 JP2021543230A JP2021543230A JPWO2020154535A5 JP WO2020154535 A5 JPWO2020154535 A5 JP WO2020154535A5 JP 2021543230 A JP2021543230 A JP 2021543230A JP 2021543230 A JP2021543230 A JP 2021543230A JP WO2020154535 A5 JPWO2020154535 A5 JP WO2020154535A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- nucleic acid
- raav
- mammal
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795695P | 2019-01-23 | 2019-01-23 | |
| US62/795,695 | 2019-01-23 | ||
| PCT/US2020/014838 WO2020154535A1 (en) | 2019-01-23 | 2020-01-23 | Highly efficient transduction and lateral spread in the retina by a novel aav virus enhanced by rational design |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523050A JP2022523050A (ja) | 2022-04-21 |
| JPWO2020154535A5 true JPWO2020154535A5 (zh) | 2023-02-06 |
Family
ID=71737005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543230A Pending JP2022523050A (ja) | 2019-01-23 | 2020-01-23 | 合理的設計により増強された新規なａａｖウイルスによる網膜における高効率の形質導入および側方への広がり |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220133909A1 (zh) |
| EP (1) | EP3914229A4 (zh) |
| JP (1) | JP2022523050A (zh) |
| CN (1) | CN113347962A (zh) |
| AU (1) | AU2020212026A1 (zh) |
| CA (1) | CA3125294A1 (zh) |
| WO (1) | WO2020154535A1 (zh) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7467598A (en) * | 1997-04-21 | 1998-11-13 | University Of Florida | Materials and methods for treatment of retinal diseases |
| WO2006110689A2 (en) * | 2005-04-07 | 2006-10-19 | The Trustees Of The University Of Pennsylvania | Method of increasing the function of an aav vector |
| KR20190060881A (ko) * | 2010-04-23 | 2019-06-03 | 유니버시티 오브 플로리다 리서치 파운데이션, 인크. | 레베르 선천성 흑내장-1(lca1)의 치료를 위한 재조합 아데노-관련된 바이러스-구아닐레이트 사이클라제 조성물 및 방법 |
| US10308957B2 (en) * | 2014-03-04 | 2019-06-04 | University Of Florida Research Foundation, Inc. | rAAV vectors and methods for transduction of photoreceptors and RPE cells |
| EP3137497B1 (en) * | 2014-05-02 | 2021-04-07 | Genzyme Corporation | Aav vectors for retinal and cns gene therapy |
| JP6805174B2 (ja) * | 2015-05-12 | 2020-12-23 | アメリカ合衆国 | 神経成長因子シグナルペプチド及び副甲状腺ホルモンを含むａａｖ分離株及び融合タンパク質 |
| US20170348387A1 (en) * | 2016-02-29 | 2017-12-07 | The Trustees Of The University Of Pennsylvania | Aav-mediated gene therapy for nphp5 lca-ciliopathy |
| SG11201811603WA (en) * | 2016-07-26 | 2019-02-27 | Biomarin Pharm Inc | Novel adeno-associated virus capsid proteins |
| AU2018224044B2 (en) * | 2017-02-21 | 2024-01-25 | The Uab Research Foundation | Modified AAV capsid proteins and uses thereof |
-
2020
- 2020-01-23 CN CN202080010452.1A patent/CN113347962A/zh active Pending
- 2020-01-23 US US17/425,292 patent/US20220133909A1/en active Pending
- 2020-01-23 JP JP2021543230A patent/JP2022523050A/ja active Pending
- 2020-01-23 AU AU2020212026A patent/AU2020212026A1/en active Pending
- 2020-01-23 WO PCT/US2020/014838 patent/WO2020154535A1/en unknown
- 2020-01-23 CA CA3125294A patent/CA3125294A1/en active Pending
- 2020-01-23 EP EP20744697.2A patent/EP3914229A4/en active Pending
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