JPWO2020006631A5 - - Google Patents

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Publication number
JPWO2020006631A5
JPWO2020006631A5 JP2021512244A JP2021512244A JPWO2020006631A5 JP WO2020006631 A5 JPWO2020006631 A5 JP WO2020006631A5 JP 2021512244 A JP2021512244 A JP 2021512244A JP 2021512244 A JP2021512244 A JP 2021512244A JP WO2020006631 A5 JPWO2020006631 A5 JP WO2020006631A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
repyrinast
subject
alcoholic steatohepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021512244A
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English (en)
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JP7399949B2 (ja
JP2021535175A (ja
Publication date
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Priority claimed from PCT/CA2019/050915 external-priority patent/WO2020006631A1/en
Publication of JP2021535175A publication Critical patent/JP2021535175A/ja
Publication of JPWO2020006631A5 publication Critical patent/JPWO2020006631A5/ja
Application granted granted Critical
Publication of JP7399949B2 publication Critical patent/JP7399949B2/ja
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Claims (6)

  1. レピリナストを含む、対象において小葉炎症又は非アルコール性脂肪性肝疾患を予防又は治療するための医薬組成物
  2. レピリナストの量が、対象1kgあたり1mg~20mgの間である、請求項1に記載の医薬組成物
  3. レピリナストの量が、対象1kgあたり3mg~10mgの間である、請求項2に記載の医薬組成物
  4. レピリナストの量が、対象1kgあたり約10mgである、請求項3に記載の医薬組成物
  5. 非アルコール性脂肪性肝疾患が非アルコール性脂肪性肝炎である、請求項1から4のいずれか一項に記載の医薬組成物
  6. 非アルコール性脂肪性肝疾患が、非アルコール性脂肪性肝炎由来肝細胞癌である、請求項1から5のいずれか一項に記載の医薬組成物
JP2021512244A 2018-07-06 2019-07-03 非アルコール性脂肪性肝炎治療のための組成物及び方法 Active JP7399949B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862694848P 2018-07-06 2018-07-06
US62/694,848 2018-07-06
US201962809351P 2019-02-22 2019-02-22
US62/809,351 2019-02-22
PCT/CA2019/050915 WO2020006631A1 (en) 2018-07-06 2019-07-03 Compositions and methods for treating non-alcoholic steatohepatitis

Publications (3)

Publication Number Publication Date
JP2021535175A JP2021535175A (ja) 2021-12-16
JPWO2020006631A5 true JPWO2020006631A5 (ja) 2022-07-12
JP7399949B2 JP7399949B2 (ja) 2023-12-18

Family

ID=69060680

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021512244A Active JP7399949B2 (ja) 2018-07-06 2019-07-03 非アルコール性脂肪性肝炎治療のための組成物及び方法

Country Status (6)

Country Link
US (1) US11744808B2 (ja)
EP (1) EP3817749A4 (ja)
JP (1) JP7399949B2 (ja)
CN (1) CN112654357B (ja)
CA (1) CA3105850A1 (ja)
WO (1) WO2020006631A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020191501A1 (en) * 2019-03-27 2020-10-01 Algernon Pharmaceuticals Inc. Methods and uses of bemithyl and derivatives for treating lung disease, fatty liver disease, and kidney disorders
WO2020191503A1 (en) * 2019-03-27 2020-10-01 Algernon Pharmaceuticals Inc. Methods and uses of bromantane and derivatives thereof for treating lung disease, fatty liver disease, and kidney disorders
IT202100014177A1 (it) * 2021-05-31 2022-12-01 Sunnutrapharma S R L Utilizzo della istradefillina per ridurre la fibrosi d’organo
CN115778957B (zh) * 2022-11-04 2024-06-21 天津中医药大学 千金藤素及包含其的组合物用于预防或治疗酒精性肝病的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2175229C2 (ru) * 1999-12-22 2001-10-27 Научно-исследовательский институт фармакологии РАМН Анксиолитическое средство
JP3885135B2 (ja) * 2000-10-10 2007-02-21 幸彦 松田 C型又は非b非c型肝炎ウイルスによる肝機能異常の改善剤
RU2261709C2 (ru) * 2003-08-15 2005-10-10 Государственное учреждение Научно-исследовательский институт фармакологии Российской Академии медицинских наук Психостимулирующее средство
MX2009010477A (es) * 2007-03-30 2009-10-19 Cardoz Ab Nueva combinacion para su uso en el tratamiento de trastornos inflamatorios.
WO2009007679A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a thromboxane a2 antagonist
JPWO2012157290A1 (ja) 2011-05-19 2015-02-23 富士化学工業株式会社 非アルコール性脂肪性肝炎の予防改善剤
CA2864389A1 (en) * 2012-02-20 2013-08-29 Takeda Pharmaceutical Company Limited Heterocyclic compound
RU2547141C1 (ru) * 2014-02-28 2015-04-10 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) Способ получения n-(4-бромфенил)-n-(2-адамантил)амина (бромантана)
US20180271788A1 (en) * 2015-12-11 2018-09-27 The United States of America, as represented by the Secretary, Department of Health and Vesicle containing metallic nanoparticle and method for production thereof

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