JPWO2020005819A5 - - Google Patents
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- JPWO2020005819A5 JPWO2020005819A5 JP2020567827A JP2020567827A JPWO2020005819A5 JP WO2020005819 A5 JPWO2020005819 A5 JP WO2020005819A5 JP 2020567827 A JP2020567827 A JP 2020567827A JP 2020567827 A JP2020567827 A JP 2020567827A JP WO2020005819 A5 JPWO2020005819 A5 JP WO2020005819A5
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| SG11202011460YA (en) | 2018-06-25 | 2020-12-30 | Univ Washington | De novo design of potent and selective interleukin mimetics |
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| US12234572B2 (en) * | 2018-11-20 | 2025-02-25 | University Of Washington | Split interleukin mimetics and their use |
| AU2020224681A1 (en) | 2019-02-21 | 2021-09-16 | Marengo Therapeutics, Inc. | Antibody molecules that bind to NKp30 and uses thereof |
| GB2599228B (en) | 2019-02-21 | 2024-02-07 | Marengo Therapeutics Inc | Multifunctional molecules that bind to T cell related cancer cells and uses thereof |
| US20220370563A1 (en) * | 2019-10-25 | 2022-11-24 | Neoleukin Therapeutics, Inc. | Methods of administration of il-2 receptor agonists |
| US20210188934A1 (en) | 2019-12-20 | 2021-06-24 | Regeneron Pharmaceuticals, Inc. | Novel il2 agonists and methods of use thereof |
| JP2023509708A (ja) | 2020-01-03 | 2023-03-09 | マレンゴ・セラピューティクス,インコーポレーテッド | 抗tcr抗体分子およびその使用 |
| WO2021188374A2 (en) * | 2020-03-16 | 2021-09-23 | Neoleukin Therapeutics, Inc. | Interleukin-2 receptor βeta (il-2rβ) binding polypeptides |
| CN114380919B (zh) * | 2020-10-18 | 2024-06-25 | 北京志道生物科技有限公司 | 经修饰的il-2分子及其用途 |
| CN112266413A (zh) * | 2020-10-22 | 2021-01-26 | 中国人民解放军海军军医大学 | 扩增nk细胞并增强其杀伤活性的因子、饲养细胞系及方法 |
| WO2022200525A1 (en) | 2021-03-26 | 2022-09-29 | Innate Pharma | Multispecific proteins comprising an nkp46-binding site, a cancer antgienge binding site fused to a cytokine for nk cell engaging |
| CN117616050A (zh) | 2021-06-09 | 2024-02-27 | 先天制药公司 | 与nkp46、细胞因子受体、肿瘤抗原和cd16a结合的多特异性蛋白质 |
| WO2022258691A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a |
| WO2022258678A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a |
| CN113603791A (zh) * | 2021-08-11 | 2021-11-05 | 厦门目青股权投资合伙企业(有限合伙) | 一种融合蛋白及其应用 |
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| WO2023052541A1 (en) * | 2021-09-30 | 2023-04-06 | Imcheck Therapeutics | Combination of an anti-btn3a activating antibody and an il-2 agonist for use in therapy |
| MX2024008642A (es) * | 2022-01-11 | 2024-09-23 | Outpace Bio Inc | Composiciones de citocinas dise?adas y metodos de uso. |
| WO2023150733A2 (en) * | 2022-02-04 | 2023-08-10 | The Board Of Trustees Of The Leland Stanford Junior University | Surrogate cytokine polypeptides |
| CN114333985B (zh) * | 2022-03-03 | 2022-07-12 | 北京晶泰科技有限公司 | 环肽设计方法、复合物结构的生成方法、装置及电子设备 |
| CN115124627A (zh) * | 2022-06-20 | 2022-09-30 | 中国人民解放军海军军医大学 | 一种自分泌IL2Rβγ激动剂的MSLN-CAR-NK细胞及其应用 |
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| AU2019384145A1 (en) * | 2018-11-20 | 2021-06-10 | Innovative Cellular Therapeutics Holdings, Ltd. | Modified cell expressing therapeutic agent and uses thereof |
| US20220370563A1 (en) | 2019-10-25 | 2022-11-24 | Neoleukin Therapeutics, Inc. | Methods of administration of il-2 receptor agonists |
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| CN111040981A (zh) * | 2019-12-26 | 2020-04-21 | 南昌大学 | 表达重组IL-2的重组大肠杆菌Nissle 1917及其功能验证方法 |
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