JPWO2020002270A5 - - Google Patents
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- Publication number
- JPWO2020002270A5 JPWO2020002270A5 JP2020572638A JP2020572638A JPWO2020002270A5 JP WO2020002270 A5 JPWO2020002270 A5 JP WO2020002270A5 JP 2020572638 A JP2020572638 A JP 2020572638A JP 2020572638 A JP2020572638 A JP 2020572638A JP WO2020002270 A5 JPWO2020002270 A5 JP WO2020002270A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- ethyl
- methoxyazetidine
- pyridine
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18180114 | 2018-06-27 | ||
| EP18180114.3 | 2018-06-27 | ||
| PCT/EP2019/066733 WO2020002270A1 (en) | 2018-06-27 | 2019-06-25 | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021528455A JP2021528455A (ja) | 2021-10-21 |
| JPWO2020002270A5 true JPWO2020002270A5 (enExample) | 2022-06-30 |
| JP7454512B2 JP7454512B2 (ja) | 2024-03-22 |
Family
ID=62814859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572638A Active JP7454512B2 (ja) | 2018-06-27 | 2019-06-25 | 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11655243B2 (enExample) |
| EP (1) | EP3814337B1 (enExample) |
| JP (1) | JP7454512B2 (enExample) |
| CN (1) | CN112074513B (enExample) |
| WO (1) | WO2020002270A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110753690B (zh) | 2017-06-20 | 2023-12-05 | 豪夫迈·罗氏有限公司 | 吡啶衍生物 |
| WO2020002280A1 (en) | 2018-06-27 | 2020-01-02 | F. Hoffmann-La Roche Ag | Novel azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| CN116640118B (zh) | 2018-06-27 | 2025-12-19 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| CN119161323A (zh) | 2018-06-27 | 2024-12-20 | 豪夫迈·罗氏有限公司 | 作为大麻素受体2的抑制剂的新型吡啶和吡嗪化合物 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808769A (en) * | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
| WO2008040649A2 (en) * | 2006-10-04 | 2008-04-10 | F. Hoffmann-La Roche Ag | Pyrazine-2-carboxamide derivatives as cb2 receptor modulators |
| WO2009106561A1 (en) * | 2008-02-27 | 2009-09-03 | Biovitrum Ab (Publ) | Pyrazine compounds for treating gpr119 related disorders |
| US9321727B2 (en) * | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
| BR112014005637A2 (pt) * | 2011-09-12 | 2017-03-28 | Hoffmann La Roche | 5-cicloalquila- ou 5-heterociclila-nicotinamidas |
| US9403808B2 (en) * | 2011-10-28 | 2016-08-02 | Hoffmann-La Roche Inc. | Pyrazine derivatives |
| TW201326139A (zh) * | 2011-10-28 | 2013-07-01 | Hoffmann La Roche | 新穎吡□衍生物 |
| MA38239A1 (fr) * | 2012-12-07 | 2017-03-31 | Hoffmann La Roche | Nouveaux dérivés de pyridine |
| CN104854092B (zh) * | 2012-12-07 | 2018-08-10 | 霍夫曼-拉罗奇有限公司 | 可用作cb2激动剂的吡啶-2-酰胺类 |
| MY179412A (en) | 2012-12-07 | 2020-11-05 | Hoffmann La Roche | Pyridine-2-amides useful as cb2 agonists |
| SI2928882T1 (sl) | 2012-12-07 | 2017-05-31 | F. Hoffmann-La Roche Ag | Pirazinski derivati kot agonisti receptorja CB2 |
| DK2978755T3 (en) * | 2013-03-26 | 2018-03-05 | Hoffmann La Roche | Hitherto unknown pyridine derivatives |
| CA2944256A1 (en) | 2014-04-04 | 2015-10-08 | F. Hoffmann-La Roche Ag | 5,6-disubstituted pyridine-2-carboxamides as cannabinoid receptor agonists |
| SG10201809066TA (en) * | 2014-04-04 | 2018-11-29 | Hoffmann La Roche | 5,6-Disubstituted Pyridine-2-Carboxamides and 5,6-Disubstituted Pyrazine-2-Carboxamides as Cannabinoid Receptor Agonists |
| BR112018011562B1 (pt) | 2015-12-09 | 2023-05-02 | F. Hoffmann-La Roche Ag | Novos derivados de fenil |
| CN110753690B (zh) | 2017-06-20 | 2023-12-05 | 豪夫迈·罗氏有限公司 | 吡啶衍生物 |
| WO2020002280A1 (en) | 2018-06-27 | 2020-01-02 | F. Hoffmann-La Roche Ag | Novel azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| CN119161323A (zh) | 2018-06-27 | 2024-12-20 | 豪夫迈·罗氏有限公司 | 作为大麻素受体2的抑制剂的新型吡啶和吡嗪化合物 |
| CN116640118B (zh) | 2018-06-27 | 2025-12-19 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| TWI687701B (zh) | 2018-12-05 | 2020-03-11 | 宏碁股份有限公司 | 判斷電量狀態的方法及其電子裝置 |
-
2019
- 2019-06-25 CN CN201980029322.XA patent/CN112074513B/zh active Active
- 2019-06-25 WO PCT/EP2019/066733 patent/WO2020002270A1/en not_active Ceased
- 2019-06-25 EP EP19739206.1A patent/EP3814337B1/en active Active
- 2019-06-25 JP JP2020572638A patent/JP7454512B2/ja active Active
-
2020
- 2020-12-17 US US17/125,647 patent/US11655243B2/en active Active
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