JPWO2020002270A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020002270A5 JPWO2020002270A5 JP2020572638A JP2020572638A JPWO2020002270A5 JP WO2020002270 A5 JPWO2020002270 A5 JP WO2020002270A5 JP 2020572638 A JP2020572638 A JP 2020572638A JP 2020572638 A JP2020572638 A JP 2020572638A JP WO2020002270 A5 JPWO2020002270 A5 JP WO2020002270A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- ethyl
- methoxyazetidine
- pyridine
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18180114 | 2018-06-27 | ||
| EP18180114.3 | 2018-06-27 | ||
| PCT/EP2019/066733 WO2020002270A1 (en) | 2018-06-27 | 2019-06-25 | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021528455A JP2021528455A (ja) | 2021-10-21 |
| JPWO2020002270A5 true JPWO2020002270A5 (enExample) | 2022-06-30 |
| JP7454512B2 JP7454512B2 (ja) | 2024-03-22 |
Family
ID=62814859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572638A Active JP7454512B2 (ja) | 2018-06-27 | 2019-06-25 | 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11655243B2 (enExample) |
| EP (1) | EP3814337B1 (enExample) |
| JP (1) | JP7454512B2 (enExample) |
| CN (1) | CN112074513B (enExample) |
| WO (1) | WO2020002270A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018234284A1 (en) | 2017-06-20 | 2018-12-27 | F. Hoffmann-La Roche Ag | Pyridine derivatives |
| CN112638430B (zh) * | 2018-06-27 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| SG11202009103WA (en) | 2018-06-27 | 2020-10-29 | Hoffmann La Roche | Novel pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| EP3814328A1 (en) | 2018-06-27 | 2021-05-05 | F. Hoffmann-La Roche AG | Novel azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808769A (en) * | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
| ES2344128T3 (es) * | 2006-10-04 | 2010-08-18 | F. Hoffmann-La Roche Ag | Derivados de pirazina-2-carboxamida como moduladores de receptores cb2. |
| WO2009106561A1 (en) * | 2008-02-27 | 2009-09-03 | Biovitrum Ab (Publ) | Pyrazine compounds for treating gpr119 related disorders |
| US9321727B2 (en) * | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
| BR112014005637A2 (pt) * | 2011-09-12 | 2017-03-28 | Hoffmann La Roche | 5-cicloalquila- ou 5-heterociclila-nicotinamidas |
| TW201326139A (zh) * | 2011-10-28 | 2013-07-01 | Hoffmann La Roche | 新穎吡□衍生物 |
| US9403808B2 (en) | 2011-10-28 | 2016-08-02 | Hoffmann-La Roche Inc. | Pyrazine derivatives |
| CA2885418A1 (en) | 2012-12-07 | 2014-06-12 | F. Hoffmann-La Roche Ag | Novel pyrazine derivatives as cb2 receptor agonists |
| ES2668690T3 (es) * | 2012-12-07 | 2018-05-21 | F. Hoffmann-La Roche Ag | Derivados de piridina novedosos |
| HUE033898T2 (en) | 2012-12-07 | 2018-01-29 | Hoffmann La Roche | Pyridin-2-amides useful as CB2 antagonists |
| ES2643058T3 (es) * | 2012-12-07 | 2017-11-21 | F. Hoffmann-La Roche Ag | Piridina-2-amidas útiles como agonistas de CB2 |
| SG11201507994QA (en) | 2013-03-26 | 2015-10-29 | Hoffmann La Roche | Novel pyridine derivatives |
| SG11201608108SA (en) | 2014-04-04 | 2016-10-28 | Hoffmann La Roche | Pyridine-2-amides useful as cb2 agonists |
| CN111170938A (zh) | 2014-04-04 | 2020-05-19 | 豪夫迈·罗氏有限公司 | 作为大麻素受体激动剂的5,6-双取代的吡啶-2-甲酰胺 |
| HRP20200606T1 (hr) | 2015-12-09 | 2020-07-10 | F. Hoffmann - La Roche Ag | Derivati fenila kao agonisti kanabinoidnog receptora 2 |
| WO2018234284A1 (en) | 2017-06-20 | 2018-12-27 | F. Hoffmann-La Roche Ag | Pyridine derivatives |
| CN112638430B (zh) | 2018-06-27 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| SG11202009103WA (en) | 2018-06-27 | 2020-10-29 | Hoffmann La Roche | Novel pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| EP3814328A1 (en) | 2018-06-27 | 2021-05-05 | F. Hoffmann-La Roche AG | Novel azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| TWI687701B (zh) | 2018-12-05 | 2020-03-11 | 宏碁股份有限公司 | 判斷電量狀態的方法及其電子裝置 |
-
2019
- 2019-06-25 CN CN201980029322.XA patent/CN112074513B/zh active Active
- 2019-06-25 JP JP2020572638A patent/JP7454512B2/ja active Active
- 2019-06-25 EP EP19739206.1A patent/EP3814337B1/en active Active
- 2019-06-25 WO PCT/EP2019/066733 patent/WO2020002270A1/en not_active Ceased
-
2020
- 2020-12-17 US US17/125,647 patent/US11655243B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6426618B2 (ja) | 新規なピリジン誘導体 | |
| CA2735764C (en) | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors | |
| US11655243B2 (en) | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists | |
| JP7445610B2 (ja) | 医療に有用な新規化合物 | |
| JP6322646B2 (ja) | Ｃｂ２受容体アゴニストとしての新規ピラジン誘導体 | |
| JP2022003066A (ja) | カンナビノイド受容体２アゴニストとしてのフェニル誘導体 | |
| US12180196B2 (en) | Azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 | |
| JPWO2020002270A5 (enExample) | ||
| HK40035571A (en) | Novel azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 | |
| RU2797345C2 (ru) | Новые соединения пиридинов и пиразинов в качестве ингибиторов каннабиноидного рецептора 2 | |
| HK40035575A (en) | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |