JPWO2019200274A5 - - Google Patents

Info

Publication number

JPWO2019200274A5

JPWO2019200274A5 JP2021505625A JP2021505625A JPWO2019200274A5 JP WO2019200274 A5 JPWO2019200274 A5 JP WO2019200274A5 JP 2021505625 A JP2021505625 A JP 2021505625A JP 2021505625 A JP2021505625 A JP 2021505625A JP WO2019200274 A5 JPWO2019200274 A5 JP WO2019200274A5

Authority

JP

Japan

Prior art keywords

pharmaceutical composition

composition according

kda

item

hyaluronic acid

Prior art date

2022-04-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 239000008194 pharmaceutical composition Substances 0.000 claims description 20
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 11
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 11
• 229920002674 hyaluronan Polymers 0.000 claims description 11
• 229960003160 hyaluronic acid Drugs 0.000 claims description 11
• 208000035475 disorder Diseases 0.000 claims description 7
• 210000004177 elastic tissue Anatomy 0.000 claims description 7
• 239000000443 aerosol Substances 0.000 claims description 6
• 150000003839 salts Chemical class 0.000 claims description 5
• 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims description 4
• 201000010099 disease Diseases 0.000 claims description 4
• 239000007788 liquid Substances 0.000 claims description 4
• 208000003470 Buschke-Ollendorff syndrome Diseases 0.000 claims description 2
• 208000002330 Congenital Heart Defects Diseases 0.000 claims description 2
• 206010056878 Dermatofibrosis lenticularis disseminata Diseases 0.000 claims description 2
• 206010014561 Emphysema Diseases 0.000 claims description 2
• 206010020772 Hypertension Diseases 0.000 claims description 2
• 208000001826 Marfan syndrome Diseases 0.000 claims description 2
• 206010028980 Neoplasm Diseases 0.000 claims description 2
• 206010049644 Williams syndrome Diseases 0.000 claims description 2
• 208000006682 alpha 1-Antitrypsin Deficiency Diseases 0.000 claims description 2
• 210000000621 bronchi Anatomy 0.000 claims description 2
• 208000028831 congenital heart disease Diseases 0.000 claims description 2
• 201000010251 cutis laxa Diseases 0.000 claims description 2
• 229940112141 dry powder inhaler Drugs 0.000 claims description 2
• 208000019423 liver disease Diseases 0.000 claims description 2
• 239000006199 nebulizer Substances 0.000 claims description 2
• 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
• 230000002685 pulmonary effect Effects 0.000 claims description 2
• 239000007921 spray Substances 0.000 claims description 2
• 238000005507 spraying Methods 0.000 claims description 2
• 210000003437 trachea Anatomy 0.000 claims description 2
• 229940079593 drug Drugs 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 1
• 239000000203 mixture Substances 0.000 claims 1
• 210000003695 paranasal sinus Anatomy 0.000 claims 1
• 238000000034 method Methods 0.000 description 6