JP2021521280A - 弾性線維分解を治療するための組成物及び方法 - Google Patents

弾性線維分解を治療するための組成物及び方法 Download PDF

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JP2021521280A
JP2021521280A JP2021505625A JP2021505625A JP2021521280A JP 2021521280 A JP2021521280 A JP 2021521280A JP 2021505625 A JP2021505625 A JP 2021505625A JP 2021505625 A JP2021505625 A JP 2021505625A JP 2021521280 A JP2021521280 A JP 2021521280A
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acid
kda
pharmaceutical composition
composition according
administration
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JPWO2019200274A5 (https=
JP2021521280A5 (https=
Inventor
カントール，ジェローム，オー．
トゥリーノ，ジェラード，エム．
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マトルクス セラピューティクス コーポレーション
マトルクス セラピューティクス コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021505625A 2018-04-12 2019-04-12 弾性線維分解を治療するための組成物及び方法 Pending JP2021521280A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862656654P 2018-04-12 2018-04-12
US62/656,654 2018-04-12
PCT/US2019/027257 WO2019200274A1 (en) 2018-04-12 2019-04-12 Compositions and methods for treating elastic fiber breakdown

Publications (3)

Publication Number Publication Date
JP2021521280A true JP2021521280A (ja) 2021-08-26
JPWO2019200274A5 JPWO2019200274A5 (https=) 2022-04-22
JP2021521280A5 JP2021521280A5 (https=) 2022-04-22

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JP2021505625A Pending JP2021521280A (ja) 2018-04-12 2019-04-12 弾性線維分解を治療するための組成物及び方法

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US (3) US10933084B2 (https=)
EP (1) EP3773614A1 (https=)
JP (1) JP2021521280A (https=)
WO (1) WO2019200274A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10933084B2 (en) * 2018-04-12 2021-03-02 MatRx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
CN111265590B (zh) * 2020-01-21 2022-03-01 华熙生物科技股份有限公司 一种用于鼻腔喷雾透明质酸冻干制剂及其制备方法和应用
CN117693352A (zh) * 2021-07-14 2024-03-12 瑞道克斯-科有限公司 针对气道疾病的谷胱甘肽c4

Citations (2)

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JP2004513071A (ja) * 2000-05-23 2004-04-30 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 肺の弾性繊維損傷に関連した呼吸器疾患の治療方法
JP2014523435A (ja) * 2011-07-12 2014-09-11 アイホル コーポレーション 粘膜関連疾患を治療および予防するための物質

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ZA791659B (en) 1978-04-17 1980-04-30 Ici Ltd Process and apparatus for spraying liquid
US4172896A (en) 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
GB9217295D0 (en) 1992-08-14 1992-09-30 Wellcome Found Controlled released tablets
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
US5358970A (en) 1993-08-12 1994-10-25 Burroughs Wellcome Co. Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
GB9315856D0 (en) 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5541231A (en) 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406171D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5970974A (en) 1995-03-14 1999-10-26 Siemens Aktiengesellschaft Dosating unit for an ultrasonic atomizer device
DE69605025T2 (de) 1995-03-14 2000-07-20 Siemens Ag Ultraschallzerstäuber mit abnehmbarer präzisionsdosiereinheit
WO1997039745A1 (en) 1996-04-19 1997-10-30 Sloan-Kettering Institute For Cancer Research Use of inhaled retinoids in the prevention of cancer
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US6110973A (en) 1998-01-29 2000-08-29 Sepracor Methods for treating obesity and weight gain using optically pure (-)-bupropion
RO121834B1 (ro) 1998-03-16 2008-06-30 Inhale Therapeutic Systems, Inc. Dispozitiv pentru administrarea unui agent activ
WO2002102317A2 (en) 2001-06-15 2002-12-27 Exhale Therapeutics, Inc. Treatment of respiratory conditions associated with bronchoconstriction with aerosolized hyaluronic acid
PL1811987T3 (pl) 2004-11-18 2008-08-29 Uni Pharma Kleon Tsetis Pharmaceutical Laboratories S A Suchy proszek zawierający sól sodową lewotyroksyny podawany przez inhalator
US20150025019A1 (en) * 2013-07-18 2015-01-22 Jerome Owen Cantor Method for Dosage Adjustment of Drugs that Prevent Elastic Fiber Breakdown
US10933084B2 (en) * 2018-04-12 2021-03-02 MatRx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004513071A (ja) * 2000-05-23 2004-04-30 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 肺の弾性繊維損傷に関連した呼吸器疾患の治療方法
JP2014523435A (ja) * 2011-07-12 2014-09-11 アイホル コーポレーション 粘膜関連疾患を治療および予防するための物質

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
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INTERNATIONAL JOURNAL OF COPD, vol. 12, JPN6023007982, 2017, pages 2747 - 2752, ISSN: 0005211177 *
LUNG, vol. Vol.189(1), JPN6023007981, 2011, pages 51 - 56, ISSN: 0005001188 *

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Publication number Publication date
US10933084B2 (en) 2021-03-02
US20240197770A1 (en) 2024-06-20
US20190314403A1 (en) 2019-10-17
WO2019200274A1 (en) 2019-10-17
US20210177887A1 (en) 2021-06-17
EP3773614A1 (en) 2021-02-17

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