JPWO2019154899A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2019154899A5 JPWO2019154899A5 JP2020538823A JP2020538823A JPWO2019154899A5 JP WO2019154899 A5 JPWO2019154899 A5 JP WO2019154899A5 JP 2020538823 A JP2020538823 A JP 2020538823A JP 2020538823 A JP2020538823 A JP 2020538823A JP WO2019154899 A5 JPWO2019154899 A5 JP WO2019154899A5
- Authority
- JP
- Japan
- Prior art keywords
- contraceptive
- composition
- coc
- vte
- risk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003433 contraceptive agent Substances 0.000 claims 24
- 239000000203 mixture Substances 0.000 claims 24
- 230000002254 contraceptive effect Effects 0.000 claims 20
- 206010014522 Embolism venous Diseases 0.000 claims 15
- 208000004043 venous thromboembolism Diseases 0.000 claims 15
- AJIPIJNNOJSSQC-NYLIRDPKSA-N estetrol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)[C@@H]4O)O)[C@@H]4[C@@H]3CCC2=C1 AJIPIJNNOJSSQC-NYLIRDPKSA-N 0.000 claims 6
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 claims 5
- 229960004845 drospirenone Drugs 0.000 claims 5
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 claims 5
- 229950009589 estetrol Drugs 0.000 claims 5
- 229940124558 contraceptive agent Drugs 0.000 claims 4
- 229940053934 norethindrone Drugs 0.000 claims 4
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 claims 4
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 3
- 229940011871 estrogen Drugs 0.000 claims 3
- 239000000262 estrogen Substances 0.000 claims 3
- 230000002439 hemostatic effect Effects 0.000 claims 3
- 229960004400 levonorgestrel Drugs 0.000 claims 3
- 239000000583 progesterone congener Substances 0.000 claims 3
- 208000007536 Thrombosis Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229960000417 norgestimate Drugs 0.000 claims 1
- KIQQMECNKUGGKA-NMYWJIRASA-N norgestimate Chemical compound O/N=C/1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(OC(C)=O)C#C)[C@@H]4[C@@H]3CCC2=C\1 KIQQMECNKUGGKA-NMYWJIRASA-N 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023168039A JP7651645B2 (ja) | 2018-02-07 | 2023-09-28 | 心臓血管系への影響を低減した避妊薬組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18155571.5 | 2018-02-07 | ||
| EP18155571 | 2018-02-07 | ||
| EP18160586.6 | 2018-03-07 | ||
| EP18160586 | 2018-03-07 | ||
| PCT/EP2019/052980 WO2019154899A1 (en) | 2018-02-07 | 2019-02-07 | Contraceptive composition with reduced cardiovascular effects |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023168039A Division JP7651645B2 (ja) | 2018-02-07 | 2023-09-28 | 心臓血管系への影響を低減した避妊薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021513507A JP2021513507A (ja) | 2021-05-27 |
| JP2021513507A5 JP2021513507A5 (https=) | 2022-02-15 |
| JPWO2019154899A5 true JPWO2019154899A5 (https=) | 2022-02-15 |
Family
ID=65278388
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538823A Pending JP2021513507A (ja) | 2018-02-07 | 2019-02-07 | 心臓血管系への影響を低減した避妊薬組成物 |
| JP2023168039A Active JP7651645B2 (ja) | 2018-02-07 | 2023-09-28 | 心臓血管系への影響を低減した避妊薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023168039A Active JP7651645B2 (ja) | 2018-02-07 | 2023-09-28 | 心臓血管系への影響を低減した避妊薬組成物 |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP4140489A1 (https=) |
| JP (2) | JP2021513507A (https=) |
| KR (1) | KR102717921B1 (https=) |
| CN (2) | CN111683664A (https=) |
| AU (1) | AU2019219070B2 (https=) |
| CA (2) | CA3178181A1 (https=) |
| CL (1) | CL2020002017A1 (https=) |
| EC (1) | ECSP20054822A (https=) |
| GE (2) | GEAP202215414A (https=) |
| IL (1) | IL276584B2 (https=) |
| JO (1) | JOP20200169A1 (https=) |
| MA (1) | MA51733A (https=) |
| NZ (1) | NZ766027A (https=) |
| PH (1) | PH12020500601A1 (https=) |
| PY (1) | PY1908892A (https=) |
| SG (1) | SG11202007163WA (https=) |
| TW (1) | TWI845496B (https=) |
| UA (1) | UA126746C2 (https=) |
| UY (1) | UY38075A (https=) |
| WO (1) | WO2019154899A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116077454A (zh) | 2015-06-18 | 2023-05-09 | 埃斯特拉有限责任公司 | 含雌四醇组分的口腔分散剂量单位 |
| HUE054589T2 (hu) | 2015-06-18 | 2021-09-28 | Estetra Sprl | Szájban diszpergálódó esztetrol tartalmú tabletta |
| RS61777B1 (sr) | 2015-06-18 | 2021-06-30 | Estetra Sprl | Oralno-disperzibilna tableta koja sadrži estetrol |
| MD3310333T2 (ro) | 2015-06-18 | 2020-06-30 | Estetra Sprl | Unitate de dozare orodispersabilă care conține un component estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| DK3781171T3 (da) | 2018-04-19 | 2022-05-02 | Estetra Srl | Sammensætninger og deres anvendelser til lindring af menopause-associerede symptomer |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
| TWI893101B (zh) * | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| WO2022248733A1 (en) | 2021-05-28 | 2022-12-01 | Neuralis Sa | Use of estetrol in treatment of respiratory infection diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4344405C2 (de) | 1993-12-24 | 1995-12-07 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption |
| EP1390042B1 (en) * | 2001-05-23 | 2007-11-28 | Pantarhei Bioscience B.V. | Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception |
| EP1535618A1 (en) * | 2003-11-26 | 2005-06-01 | Schering Aktiengesellschaft | Pharmaceutical preparation for continuous hormonal treatment over a period of longer than 21-28 days comprising two estrogen and/or progestin compositions |
| EP2432474A1 (de) * | 2009-05-22 | 2012-03-28 | Bayer Pharma Aktiengesellschaft | Arzneimittel zur oralen verabreichung, enthaltend mindestens ein estrogen und/oder mindestens ein gestagen und mindestens einen probiotischen bakterien-stamm |
| WO2012055840A1 (en) * | 2010-10-28 | 2012-05-03 | Bayer Pharma Aktiengesellschaft | Composition and preparation for treatment of dysmenorrhea and menstrual pain and use of a hormonal agent and a zinc salt for treatment of menstrual disorders |
| NO3079671T3 (https=) * | 2013-12-12 | 2018-03-24 | ||
| CA3178291A1 (en) * | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| KR102780201B1 (ko) | 2016-10-28 | 2025-03-12 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
-
2019
- 2019-02-07 CN CN201980012248.0A patent/CN111683664A/zh active Pending
- 2019-02-07 CA CA3178181A patent/CA3178181A1/en active Pending
- 2019-02-07 EP EP22199066.6A patent/EP4140489A1/en active Pending
- 2019-02-07 KR KR1020207025456A patent/KR102717921B1/ko active Active
- 2019-02-07 NZ NZ766027A patent/NZ766027A/en unknown
- 2019-02-07 EP EP19703103.2A patent/EP3749327A1/en active Pending
- 2019-02-07 IL IL276584A patent/IL276584B2/en unknown
- 2019-02-07 JO JOP/2020/0169A patent/JOP20200169A1/ar unknown
- 2019-02-07 UY UY38075A patent/UY38075A/es not_active Application Discontinuation
- 2019-02-07 AU AU2019219070A patent/AU2019219070B2/en active Active
- 2019-02-07 PY PY201901908892A patent/PY1908892A/es unknown
- 2019-02-07 CN CN202211257175.1A patent/CN115429806A/zh active Pending
- 2019-02-07 MA MA051733A patent/MA51733A/fr unknown
- 2019-02-07 CA CA3089804A patent/CA3089804A1/en active Pending
- 2019-02-07 GE GEAP202215414A patent/GEAP202215414A/en unknown
- 2019-02-07 GE GEAP201915414A patent/GEP20227407B/en unknown
- 2019-02-07 SG SG11202007163WA patent/SG11202007163WA/en unknown
- 2019-02-07 WO PCT/EP2019/052980 patent/WO2019154899A1/en not_active Ceased
- 2019-02-07 JP JP2020538823A patent/JP2021513507A/ja active Pending
- 2019-02-07 UA UAA202005421A patent/UA126746C2/uk unknown
- 2019-02-11 TW TW108104465A patent/TWI845496B/zh active
-
2020
- 2020-07-13 PH PH12020500601A patent/PH12020500601A1/en unknown
- 2020-07-31 CL CL2020002017A patent/CL2020002017A1/es unknown
- 2020-09-04 EC ECSENADI202054822A patent/ECSP20054822A/es unknown
-
2023
- 2023-09-28 JP JP2023168039A patent/JP7651645B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021513507A5 (https=) | ||
| JP7177313B2 (ja) | 避妊用組成物および避妊方法 | |
| Wiegratz et al. | Hormonal contraception—what kind, when, and for whom? | |
| Sitruk-Ware | Mifepristone and misoprostol sequential regimen side effects, complications and safety | |
| Palacios et al. | Efficacy and cardiovascular safety of the new estrogen-free contraceptive pill containing 4 mg drospirenone alone in a 24/4 regime | |
| US20120028935A1 (en) | Therapeutic Gestagens for the Treatment of Premenstrual Dysphoric Disorder | |
| JP2007512291A (ja) | ２種のエストロゲン及び／又はプロゲスチン組成物を含んで成る、２１〜２８日よりも長い期間にわたっての連続ホルモン処理のための医薬製剤 | |
| JP2019163318A5 (https=) | ||
| KR20190076014A (ko) | 월경통 및 생리통의 관리방법 | |
| ZA200404249B (en) | Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology | |
| JPWO2019154899A5 (https=) | ||
| Sulak | Continuous oral contraception: changing times | |
| Haider et al. | Non–contraceptive benefits and risks of contraception | |
| ESHRE Capri Workshop Group | Hormonal contraception without estrogens | |
| Mircette™ Study Group | An open-label, multicenter, noncomparative safety and efficacy study of Mircette™, a low-dose estrogen-progestin oral contraceptive | |
| TWI351960B (en) | Multiphase product for contraception based on a na | |
| Hite et al. | Large observational trial of a new low-dose oral contraceptive containing 20 μg ethinylestradiol and 100 μg levonorgestrel (Miranovar) in Germany | |
| US20070111974A1 (en) | Therapeutic gestagens for the treatment of premenstrual dysphoric disorder | |
| JP2013047269A (ja) | 経口避妊薬の形での機能不全子宮出血の経口治療のためへの吉草酸エストラジオール又はエストラジオールとジエノゲストとの使用 | |
| Hasan et al. | Mucous membrane pemphigoid with exclusive gingival involvement: Report of a case and review of literature | |
| Barnhart et al. | Emergency contraception | |
| Islam et al. | Oral Bullous Lichen Planus–A Case Report | |
| Greenblatt | The Development of a New Triphasic Oral Contraceptive: The Proceedings of a Special Symposium held at the 10th World Congress on Fertility and Sterility, Madrid July 1980 | |
| CN101119732A (zh) | 避孕药物制剂 | |
| Sulak | Oral contraceptive update: new agents and regimens |