IL276584B2 - Contraceptive composition with reduced cardiovascular effects - Google Patents
Contraceptive composition with reduced cardiovascular effectsInfo
- Publication number
- IL276584B2 IL276584B2 IL276584A IL27658420A IL276584B2 IL 276584 B2 IL276584 B2 IL 276584B2 IL 276584 A IL276584 A IL 276584A IL 27658420 A IL27658420 A IL 27658420A IL 276584 B2 IL276584 B2 IL 276584B2
- Authority
- IL
- Israel
- Prior art keywords
- composition
- component
- effective amount
- estetrol
- risk
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- General Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18155571 | 2018-02-07 | ||
| EP18160586 | 2018-03-07 | ||
| PCT/EP2019/052980 WO2019154899A1 (en) | 2018-02-07 | 2019-02-07 | Contraceptive composition with reduced cardiovascular effects |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL276584A IL276584A (en) | 2020-09-30 |
| IL276584B1 IL276584B1 (en) | 2024-06-01 |
| IL276584B2 true IL276584B2 (en) | 2024-10-01 |
Family
ID=65278388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL276584A IL276584B2 (en) | 2018-02-07 | 2019-02-07 | Contraceptive composition with reduced cardiovascular effects |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP4140489A1 (https=) |
| JP (2) | JP2021513507A (https=) |
| KR (1) | KR102717921B1 (https=) |
| CN (2) | CN111683664A (https=) |
| AU (1) | AU2019219070B2 (https=) |
| CA (2) | CA3178181A1 (https=) |
| CL (1) | CL2020002017A1 (https=) |
| EC (1) | ECSP20054822A (https=) |
| GE (2) | GEAP202215414A (https=) |
| IL (1) | IL276584B2 (https=) |
| JO (1) | JOP20200169A1 (https=) |
| MA (1) | MA51733A (https=) |
| NZ (1) | NZ766027A (https=) |
| PH (1) | PH12020500601A1 (https=) |
| PY (1) | PY1908892A (https=) |
| SG (1) | SG11202007163WA (https=) |
| TW (1) | TWI845496B (https=) |
| UA (1) | UA126746C2 (https=) |
| UY (1) | UY38075A (https=) |
| WO (1) | WO2019154899A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116077454A (zh) | 2015-06-18 | 2023-05-09 | 埃斯特拉有限责任公司 | 含雌四醇组分的口腔分散剂量单位 |
| HUE054589T2 (hu) | 2015-06-18 | 2021-09-28 | Estetra Sprl | Szájban diszpergálódó esztetrol tartalmú tabletta |
| RS61777B1 (sr) | 2015-06-18 | 2021-06-30 | Estetra Sprl | Oralno-disperzibilna tableta koja sadrži estetrol |
| MD3310333T2 (ro) | 2015-06-18 | 2020-06-30 | Estetra Sprl | Unitate de dozare orodispersabilă care conține un component estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| DK3781171T3 (da) | 2018-04-19 | 2022-05-02 | Estetra Srl | Sammensætninger og deres anvendelser til lindring af menopause-associerede symptomer |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
| TWI893101B (zh) * | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| WO2022248733A1 (en) | 2021-05-28 | 2022-12-01 | Neuralis Sa | Use of estetrol in treatment of respiratory infection diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4344405C2 (de) | 1993-12-24 | 1995-12-07 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption |
| EP1390042B1 (en) * | 2001-05-23 | 2007-11-28 | Pantarhei Bioscience B.V. | Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception |
| EP1535618A1 (en) * | 2003-11-26 | 2005-06-01 | Schering Aktiengesellschaft | Pharmaceutical preparation for continuous hormonal treatment over a period of longer than 21-28 days comprising two estrogen and/or progestin compositions |
| EP2432474A1 (de) * | 2009-05-22 | 2012-03-28 | Bayer Pharma Aktiengesellschaft | Arzneimittel zur oralen verabreichung, enthaltend mindestens ein estrogen und/oder mindestens ein gestagen und mindestens einen probiotischen bakterien-stamm |
| WO2012055840A1 (en) * | 2010-10-28 | 2012-05-03 | Bayer Pharma Aktiengesellschaft | Composition and preparation for treatment of dysmenorrhea and menstrual pain and use of a hormonal agent and a zinc salt for treatment of menstrual disorders |
| NO3079671T3 (https=) * | 2013-12-12 | 2018-03-24 | ||
| CA3178291A1 (en) * | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| KR102780201B1 (ko) | 2016-10-28 | 2025-03-12 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
-
2019
- 2019-02-07 CN CN201980012248.0A patent/CN111683664A/zh active Pending
- 2019-02-07 CA CA3178181A patent/CA3178181A1/en active Pending
- 2019-02-07 EP EP22199066.6A patent/EP4140489A1/en active Pending
- 2019-02-07 KR KR1020207025456A patent/KR102717921B1/ko active Active
- 2019-02-07 NZ NZ766027A patent/NZ766027A/en unknown
- 2019-02-07 EP EP19703103.2A patent/EP3749327A1/en active Pending
- 2019-02-07 IL IL276584A patent/IL276584B2/en unknown
- 2019-02-07 JO JOP/2020/0169A patent/JOP20200169A1/ar unknown
- 2019-02-07 UY UY38075A patent/UY38075A/es not_active Application Discontinuation
- 2019-02-07 AU AU2019219070A patent/AU2019219070B2/en active Active
- 2019-02-07 PY PY201901908892A patent/PY1908892A/es unknown
- 2019-02-07 CN CN202211257175.1A patent/CN115429806A/zh active Pending
- 2019-02-07 MA MA051733A patent/MA51733A/fr unknown
- 2019-02-07 CA CA3089804A patent/CA3089804A1/en active Pending
- 2019-02-07 GE GEAP202215414A patent/GEAP202215414A/en unknown
- 2019-02-07 GE GEAP201915414A patent/GEP20227407B/en unknown
- 2019-02-07 SG SG11202007163WA patent/SG11202007163WA/en unknown
- 2019-02-07 WO PCT/EP2019/052980 patent/WO2019154899A1/en not_active Ceased
- 2019-02-07 JP JP2020538823A patent/JP2021513507A/ja active Pending
- 2019-02-07 UA UAA202005421A patent/UA126746C2/uk unknown
- 2019-02-11 TW TW108104465A patent/TWI845496B/zh active
-
2020
- 2020-07-13 PH PH12020500601A patent/PH12020500601A1/en unknown
- 2020-07-31 CL CL2020002017A patent/CL2020002017A1/es unknown
- 2020-09-04 EC ECSENADI202054822A patent/ECSP20054822A/es unknown
-
2023
- 2023-09-28 JP JP2023168039A patent/JP7651645B2/ja active Active
Non-Patent Citations (1)
| Title |
|---|
| KLUFT CORNELIS ET AL,, REDUCED HEMOSTATIC EFFECTS WITH DROSPIRENONE-BASED ORAL CONTRACEPTIVES CONTAINING ESTETROL VS. ETHINYL ESTRADIOL, 1 September 2016 (2016-09-01) * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3749327A1 (en) | 2020-12-16 |
| EP4140489A1 (en) | 2023-03-01 |
| CN115429806A (zh) | 2022-12-06 |
| JP7651645B2 (ja) | 2025-03-26 |
| AU2019219070B2 (en) | 2024-12-19 |
| CN111683664A (zh) | 2020-09-18 |
| CA3178181A1 (en) | 2019-08-15 |
| CL2020002017A1 (es) | 2020-12-04 |
| WO2019154899A1 (en) | 2019-08-15 |
| IL276584B1 (en) | 2024-06-01 |
| KR102717921B1 (ko) | 2024-10-16 |
| TWI845496B (zh) | 2024-06-21 |
| UY38075A (es) | 2019-10-01 |
| ECSP20054822A (es) | 2020-12-31 |
| AU2019219070A1 (en) | 2020-09-24 |
| TW202011967A (zh) | 2020-04-01 |
| CA3089804A1 (en) | 2019-08-15 |
| PY1908892A (es) | 2019-10-15 |
| SG11202007163WA (en) | 2020-08-28 |
| GEAP202215414A (en) | 2022-04-25 |
| PH12020500601A1 (en) | 2021-05-17 |
| MA51733A (fr) | 2020-12-16 |
| JP2024009834A (ja) | 2024-01-23 |
| KR20200118464A (ko) | 2020-10-15 |
| UA126746C2 (uk) | 2023-01-18 |
| NZ766027A (en) | 2026-03-27 |
| JP2021513507A (ja) | 2021-05-27 |
| GEP20227407B (en) | 2022-08-25 |
| IL276584A (en) | 2020-09-30 |
| JOP20200169A1 (ar) | 2020-07-07 |
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