JPWO2019140320A5 - - Google Patents

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Publication number
JPWO2019140320A5
JPWO2019140320A5 JP2020538618A JP2020538618A JPWO2019140320A5 JP WO2019140320 A5 JPWO2019140320 A5 JP WO2019140320A5 JP 2020538618 A JP2020538618 A JP 2020538618A JP 2020538618 A JP2020538618 A JP 2020538618A JP WO2019140320 A5 JPWO2019140320 A5 JP WO2019140320A5
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JP
Japan
Prior art keywords
antibody
seq
sample
heavy chain
amino acid
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JP2020538618A
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English (en)
Japanese (ja)
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JP7394767B2 (ja
JP2021510813A (ja
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Priority claimed from PCT/US2019/013373 external-priority patent/WO2019140320A1/en
Publication of JP2021510813A publication Critical patent/JP2021510813A/ja
Publication of JPWO2019140320A5 publication Critical patent/JPWO2019140320A5/ja
Priority to JP2023164188A priority Critical patent/JP2023171846A/ja
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Publication of JP7394767B2 publication Critical patent/JP7394767B2/ja
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JP2020538618A 2018-01-12 2019-01-11 ポリペプチドの定量化方法 Active JP7394767B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023164188A JP2023171846A (ja) 2018-01-12 2023-09-27 ポリペプチドの定量化方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862617080P 2018-01-12 2018-01-12
US62/617,080 2018-01-12
PCT/US2019/013373 WO2019140320A1 (en) 2018-01-12 2019-01-11 Methods for the quantitation of polypeptides

Related Child Applications (1)

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JP2023164188A Division JP2023171846A (ja) 2018-01-12 2023-09-27 ポリペプチドの定量化方法

Publications (3)

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JP2021510813A JP2021510813A (ja) 2021-04-30
JPWO2019140320A5 true JPWO2019140320A5 (es) 2022-02-07
JP7394767B2 JP7394767B2 (ja) 2023-12-08

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JP2020538618A Active JP7394767B2 (ja) 2018-01-12 2019-01-11 ポリペプチドの定量化方法
JP2023164188A Pending JP2023171846A (ja) 2018-01-12 2023-09-27 ポリペプチドの定量化方法

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JP2023164188A Pending JP2023171846A (ja) 2018-01-12 2023-09-27 ポリペプチドの定量化方法

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US (2) US11067584B2 (es)
EP (1) EP3737949A1 (es)
JP (2) JP7394767B2 (es)
KR (1) KR20200109333A (es)
CN (1) CN111801580A (es)
AU (1) AU2019206648A1 (es)
BR (1) BR112020013325A2 (es)
CA (1) CA3088107A1 (es)
IL (1) IL275536A (es)
MX (1) MX2020007444A (es)
SG (1) SG11202006410WA (es)
WO (1) WO2019140320A1 (es)
ZA (1) ZA202003701B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11067584B2 (en) 2018-01-12 2021-07-20 Genzyme Corporation Methods for the quantitation of polypeptides

Family Cites Families (27)

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US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US7632686B2 (en) 2002-10-03 2009-12-15 Anderson Forschung Group High sensitivity quantitation of peptides by mass spectrometry
JP2006033413A (ja) * 2004-07-15 2006-02-02 Daishinku Corp 圧電振動デバイス
PT1999154E (pt) 2006-03-24 2013-01-24 Merck Patent Gmbh Domínios proteicos heterodiméricos modificados
WO2007147901A1 (en) 2006-06-22 2007-12-27 Novo Nordisk A/S Production of bispecific antibodies
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
DK2235064T3 (en) 2008-01-07 2016-01-11 Amgen Inc A process for the preparation of heterodimeric Fc molecules using electrostatic control effects
US9029508B2 (en) 2008-04-29 2015-05-12 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
PE20100054A1 (es) 2008-06-03 2010-03-03 Abbott Lab Inmunoglobulina con dominio variable dual
PE20100092A1 (es) 2008-06-03 2010-03-12 Abbott Lab Inmunoglobulina con dominio variable dual y usos de la misma
ES2647243T3 (es) 2009-04-27 2017-12-20 Merz Pharma Gmbh & Co. Kgaa Medios y métodos para la determinación de la cantidad de polipéptido Neurotoxina y de sus actividades catalíticas y proteolíticas
US9150663B2 (en) 2010-04-20 2015-10-06 Genmab A/S Heterodimeric antibody Fc-containing proteins and methods for production thereof
JP2013539364A (ja) 2010-08-26 2013-10-24 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリンおよびその使用
TWI588156B (zh) 2011-03-28 2017-06-21 賽諾菲公司 具有交叉結合區定向之雙重可變區類抗體結合蛋白
CA2833212C (en) 2011-05-12 2020-06-09 Genentech, Inc. Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides
PL3129067T3 (pl) * 2014-03-19 2023-05-08 Genzyme Corporation Specyficzne dla miejsca glikomodyfikowanie ugrupowań celujących
CN107405399B (zh) * 2015-01-02 2022-02-08 武田药品工业株式会社 针对血浆激肽释放酶和因子xii的双特异性抗体
CN107428835B (zh) 2015-01-23 2021-11-26 赛诺菲 抗cd3抗体、抗cd123抗体和与cd3和/或cd123特异性结合的双特异性抗体
US10338039B2 (en) * 2015-03-09 2019-07-02 Shimadzu Corporation Method for detecting monoclonal antibody using mass spectrometry
BR112018008011A2 (pt) 2015-10-25 2018-10-30 Sanofi proteínas de ligação triespecíficas e/ou trivalentes para prevenção ou tratamento de infecção por hiv
EP3443006B1 (en) * 2016-04-13 2023-08-02 Sanofi Trispecific and/or trivalent binding proteins
US11067583B2 (en) * 2016-05-25 2021-07-20 University Of Maryland, Baltimore Methods of making active antibodies from biological fluids
US11067584B2 (en) 2018-01-12 2021-07-20 Genzyme Corporation Methods for the quantitation of polypeptides

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