JPWO2011019065A1 - 腫瘍血管新生阻害剤 - Google Patents

腫瘍血管新生阻害剤 Download PDF

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Publication number
JPWO2011019065A1
JPWO2011019065A1 JP2011526783A JP2011526783A JPWO2011019065A1 JP WO2011019065 A1 JPWO2011019065 A1 JP WO2011019065A1 JP 2011526783 A JP2011526783 A JP 2011526783A JP 2011526783 A JP2011526783 A JP 2011526783A JP WO2011019065 A1 JPWO2011019065 A1 JP WO2011019065A1
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Japan
Prior art keywords
def6
seq
amino acid
gene
cells
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Pending
Application number
JP2011526783A
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English (en)
Japanese (ja)
Inventor
京子 樋田
京子 樋田
泰浩 樋田
泰浩 樋田
嗣輝 大坪
嗣輝 大坪
青木　幹雄
幹雄 青木
岩崎　剛之
剛之 岩崎
敏裕 甲斐
敏裕 甲斐
英史 佐藤
英史 佐藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hokkaido University NUC
Sumitomo Pharma Co Ltd
Original Assignee
Hokkaido University NUC
Sumitomo Dainippon Pharma Co Ltd
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Publication date
Application filed by Hokkaido University NUC, Sumitomo Dainippon Pharma Co Ltd filed Critical Hokkaido University NUC
Publication of JPWO2011019065A1 publication Critical patent/JPWO2011019065A1/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2011526783A 2009-08-12 2010-08-11 腫瘍血管新生阻害剤 Pending JPWO2011019065A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009187061 2009-08-12
JP2009187061 2009-08-12
PCT/JP2010/063669 WO2011019065A1 (fr) 2009-08-12 2010-08-11 Inhibiteur de l'angiogenèse tumorale

Publications (1)

Publication Number Publication Date
JPWO2011019065A1 true JPWO2011019065A1 (ja) 2013-01-17

Family

ID=43586240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011526783A Pending JPWO2011019065A1 (ja) 2009-08-12 2010-08-11 腫瘍血管新生阻害剤

Country Status (2)

Country Link
JP (1) JPWO2011019065A1 (fr)
WO (1) WO2011019065A1 (fr)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6010063179; ＺＨＯＵ，Ｙ． ｅｔ ａｌ: 'Ｅｆｆｅｃｔｓ ｏｆ ＩＢＰ ａｂｓｅｎｃｅ ｍｅｄｉａｔｅｄ ｂｙ ｓｔａｂｌｅ ｓｉＲＮＡ ｖｅｃｔｏｒ ｏｎ Ｔ ｃｅｌｌ ａｐｏｐｔｏｓｉｓ' Ｍｉａｎｙｉｘｕｅ Ｚａｚｈｉ Ｖｏｌ．２３， Ｎｏ．３, 2007, ｐ．２４８-２５１ *
JPN6014037859; Ｉｎｔ Ｉｍｍｕｎｏｐｈａｒｍａｃｏｌ ｖｏｌ．９， ｎｏ．７-８, 200907, ｐ．１００２-９ *

Also Published As

Publication number Publication date
WO2011019065A1 (fr) 2011-02-17

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