JPWO2002044129A1 - 置換カルボン酸誘導体 - Google Patents

置換カルボン酸誘導体 Download PDF

Info

Publication number
JPWO2002044129A1
JPWO2002044129A1 JP2002546499A JP2002546499A JPWO2002044129A1 JP WO2002044129 A1 JPWO2002044129 A1 JP WO2002044129A1 JP 2002546499 A JP2002546499 A JP 2002546499A JP 2002546499 A JP2002546499 A JP 2002546499A JP WO2002044129 A1 JPWO2002044129 A1 JP WO2002044129A1
Authority
JP
Japan
Prior art keywords
carbon atoms
group
alkyl group
pharmaceutically acceptable
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002546499A
Other languages
English (en)
Japanese (ja)
Inventor
宮地　弘幸
村上　浩二
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of JPWO2002044129A1 publication Critical patent/JPWO2002044129A1/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2002546499A 2000-11-29 2001-11-28 置換カルボン酸誘導体 Pending JPWO2002044129A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000363676 2000-11-29
JP2000363676 2000-11-29
PCT/JP2001/010352 WO2002044129A1 (fr) 2000-11-29 2001-11-28 Dérivés d'acide carboxylique substitués

Publications (1)

Publication Number Publication Date
JPWO2002044129A1 true JPWO2002044129A1 (ja) 2004-04-02

Family

ID=18834747

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002546499A Pending JPWO2002044129A1 (ja) 2000-11-29 2001-11-28 置換カルボン酸誘導体

Country Status (3)

Country Link
JP (1) JPWO2002044129A1 (fr)
AU (1) AU2002222549A1 (fr)
WO (1) WO2002044129A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS20050318A (en) * 2002-10-21 2007-09-21 Janssen Pharmaceutica N.V., Substituted tetralins and indanes
EP1556344A1 (fr) * 2002-10-21 2005-07-27 Janssen Pharmaceutica N.V. Traitement du syndrome x a l'aide de tetralines et d'indanes substitues
ATE430728T1 (de) * 2002-10-21 2009-05-15 Janssen Pharmaceutica Nv Substituierte tetraline und indane und ihre verwendung
JP2007001912A (ja) * 2005-06-22 2007-01-11 Univ Of Tokyo 置換フェニルプロピオン酸誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000256194A (ja) * 1999-01-06 2000-09-19 Mitsui Chemicals Inc 核内レセプタ作動薬およびその効果増強剤
JP4618845B2 (ja) * 1999-06-09 2011-01-26 杏林製薬株式会社 ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
TWI262185B (en) * 1999-10-01 2006-09-21 Eisai Co Ltd Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives

Also Published As

Publication number Publication date
WO2002044129A1 (fr) 2002-06-06
AU2002222549A1 (en) 2002-06-11

Similar Documents

Publication Publication Date Title
JP4803946B2 (ja) 置換フェニルプロピオン酸誘導体
AU773445B2 (en) Substituted phenylpropanoic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) alpha
US20040235825A1 (en) Carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient
JPWO2002044127A1 (ja) 置換カルボン酸誘導体
JP2002537390A (ja) 新規三環式化合物及び薬剤におけるこれらの使用；これらの調製方法及びこれらを含む製薬組成物
JP2007514659A (ja) ペルオキシソーム増殖因子活性化受容体の修飾因子
US7176204B2 (en) Substituted carboxylic acid derivatives
JP2007126454A (ja) アニリド誘導体
JP4488732B2 (ja) ベンズオキサゾール化合物及びこれを含有する医薬組成物
US20030187068A1 (en) Substituted phenylpropionic acid derivatives
KR20010080144A (ko) 카르복실산 유도체 및 이 유도체를 활성 성분으로서포함하는 약제
JPWO2002044130A1 (ja) 置換カルボン酸誘導体
US7241784B2 (en) Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient
JPWO2002046146A1 (ja) 置換カルボン酸誘導体
JPWO2002044129A1 (ja) 置換カルボン酸誘導体
JPWO2002044131A1 (ja) 置換カルボン酸誘導体
JP4446387B2 (ja) （２ｓ）−２−エチルフェニルプロピオン酸誘導体
JP2008526904A (ja) ヒドロキシフェノール誘導体、その調製方法、それらを含む医薬組成物、およびその治療的使用
JPWO2005009942A1 (ja) 光学活性置換フェニルプロピオン酸誘導体
ES2352071T3 (es) Derivados de tirosina sustituidos con n-fenilacroloilo como agonostas de hppar alfa y de hppar gama.
JP2007001912A (ja) 置換フェニルプロピオン酸誘導体