JPS6479173A - Synthesis of chiral 1,3-dioxine-4-one - Google Patents
Synthesis of chiral 1,3-dioxine-4-oneInfo
- Publication number
- JPS6479173A JPS6479173A JP23485187A JP23485187A JPS6479173A JP S6479173 A JPS6479173 A JP S6479173A JP 23485187 A JP23485187 A JP 23485187A JP 23485187 A JP23485187 A JP 23485187A JP S6479173 A JPS6479173 A JP S6479173A
- Authority
- JP
- Japan
- Prior art keywords
- optically active
- compound
- terpene
- ketoacid
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
PURPOSE:To obtain the title compound which is used as an intermediate of physiologically active substances or functional substances, by allowing a beta- ketoacid to react with an optically active terpene-like compound to enable an optically active group to be introduced directly in the 2-position under steric inhibition. CONSTITUTION:The reaction of a beta-ketoacid, its derivative, such as beta-ketoacid tert.-butyl ester, or its equivalent substance such as formyldram acid, with an optically active terpene compound such as a terpene carbonyl such as 1- menthone is carried out in acetic anhydride under cooling, as conc. sulfuric acid is added to give the subject optically active cyclic compound of the formula (X is optically active group originating from the terpene compound; Y, Z are H, lower alkyl, acyl) such as (6S,7R,10R)-, and (6R,7R,10R)-10-methyl-7- isopropyl-4-oxo-1,5-dioxaspiro[5.5]-undecene-2.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23485187A JPS6479173A (en) | 1987-09-21 | 1987-09-21 | Synthesis of chiral 1,3-dioxine-4-one |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23485187A JPS6479173A (en) | 1987-09-21 | 1987-09-21 | Synthesis of chiral 1,3-dioxine-4-one |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6479173A true JPS6479173A (en) | 1989-03-24 |
Family
ID=16977349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP23485187A Pending JPS6479173A (en) | 1987-09-21 | 1987-09-21 | Synthesis of chiral 1,3-dioxine-4-one |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6479173A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6354368A (en) * | 1986-07-23 | 1988-03-08 | シユツウデイエンゲゼルシヤフト・コ−ル・ミット・ベシユレンクテル・ハフツング | Optically pure 1,3-dioxenone, manufacture and use |
-
1987
- 1987-09-21 JP JP23485187A patent/JPS6479173A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6354368A (en) * | 1986-07-23 | 1988-03-08 | シユツウデイエンゲゼルシヤフト・コ−ル・ミット・ベシユレンクテル・ハフツング | Optically pure 1,3-dioxenone, manufacture and use |
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