JPS6479173A - Synthesis of chiral 1,3-dioxine-4-one - Google Patents

Synthesis of chiral 1,3-dioxine-4-one

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Publication number
JPS6479173A
JPS6479173A JP23485187A JP23485187A JPS6479173A JP S6479173 A JPS6479173 A JP S6479173A JP 23485187 A JP23485187 A JP 23485187A JP 23485187 A JP23485187 A JP 23485187A JP S6479173 A JPS6479173 A JP S6479173A
Authority
JP
Japan
Prior art keywords
optically active
compound
terpene
ketoacid
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP23485187A
Other languages
Japanese (ja)
Inventor
Chikara Kaneko
Masayuki Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JNC Corp
Original Assignee
Chisso Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chisso Corp filed Critical Chisso Corp
Priority to JP23485187A priority Critical patent/JPS6479173A/en
Publication of JPS6479173A publication Critical patent/JPS6479173A/en
Pending legal-status Critical Current

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  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

PURPOSE:To obtain the title compound which is used as an intermediate of physiologically active substances or functional substances, by allowing a beta- ketoacid to react with an optically active terpene-like compound to enable an optically active group to be introduced directly in the 2-position under steric inhibition. CONSTITUTION:The reaction of a beta-ketoacid, its derivative, such as beta-ketoacid tert.-butyl ester, or its equivalent substance such as formyldram acid, with an optically active terpene compound such as a terpene carbonyl such as 1- menthone is carried out in acetic anhydride under cooling, as conc. sulfuric acid is added to give the subject optically active cyclic compound of the formula (X is optically active group originating from the terpene compound; Y, Z are H, lower alkyl, acyl) such as (6S,7R,10R)-, and (6R,7R,10R)-10-methyl-7- isopropyl-4-oxo-1,5-dioxaspiro[5.5]-undecene-2.
JP23485187A 1987-09-21 1987-09-21 Synthesis of chiral 1,3-dioxine-4-one Pending JPS6479173A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23485187A JPS6479173A (en) 1987-09-21 1987-09-21 Synthesis of chiral 1,3-dioxine-4-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23485187A JPS6479173A (en) 1987-09-21 1987-09-21 Synthesis of chiral 1,3-dioxine-4-one

Publications (1)

Publication Number Publication Date
JPS6479173A true JPS6479173A (en) 1989-03-24

Family

ID=16977349

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23485187A Pending JPS6479173A (en) 1987-09-21 1987-09-21 Synthesis of chiral 1,3-dioxine-4-one

Country Status (1)

Country Link
JP (1) JPS6479173A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354368A (en) * 1986-07-23 1988-03-08 シユツウデイエンゲゼルシヤフト・コ−ル・ミット・ベシユレンクテル・ハフツング Optically pure 1,3-dioxenone, manufacture and use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354368A (en) * 1986-07-23 1988-03-08 シユツウデイエンゲゼルシヤフト・コ−ル・ミット・ベシユレンクテル・ハフツング Optically pure 1,3-dioxenone, manufacture and use

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