JPS6447746A - Production of 5-amino-2,4,-triiodoisophthalic acid - Google Patents
Production of 5-amino-2,4,-triiodoisophthalic acidInfo
- Publication number
- JPS6447746A JPS6447746A JP20422687A JP20422687A JPS6447746A JP S6447746 A JPS6447746 A JP S6447746A JP 20422687 A JP20422687 A JP 20422687A JP 20422687 A JP20422687 A JP 20422687A JP S6447746 A JPS6447746 A JP S6447746A
- Authority
- JP
- Japan
- Prior art keywords
- filtrate
- aipa
- amino
- active carbon
- raw material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To obtain 5-amino-2,4,6-triiodophthalic acid (AIPA) useful as an intermediate for Roentgen contrast medium having extremely low intravenous toxicity, by treating filtrate after crystal separation obtained by producing AIPA with an active carbon and then concentrating the filtrate in order to re-utilizing the filtrate. CONSTITUTION:When 5-amino-2,4,6-triiodoisophthalic acid (AIPA) is produced, a filtrate obtained by separating a product crystal is treated with an active carbon or ion exchange resin to decolorize and purify the filtrate. Then the filtrate is concentrated and excess water and hydrochloric acid is distilled out to give about 20wt.% aqueous hydrochloric acid solution containing AIPA and other unreacted material, which is then re-utilized as a raw material of AIPA for dissolving iodine monochloride or as a reaction solvent. By the above- mentioned method, unit consumption of the raw material is improved and waste treating process is simplified or obviated.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62204226A JPH0788337B2 (en) | 1987-08-19 | 1987-08-19 | Process for producing 5-amino-2,4,6-triiodoisophthalic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62204226A JPH0788337B2 (en) | 1987-08-19 | 1987-08-19 | Process for producing 5-amino-2,4,6-triiodoisophthalic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6447746A true JPS6447746A (en) | 1989-02-22 |
JPH0788337B2 JPH0788337B2 (en) | 1995-09-27 |
Family
ID=16486928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62204226A Expired - Fee Related JPH0788337B2 (en) | 1987-08-19 | 1987-08-19 | Process for producing 5-amino-2,4,6-triiodoisophthalic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0788337B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04303772A (en) * | 1991-03-30 | 1992-10-27 | Shimadzu Corp | Automatic analyzer for biochemistry |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB785670A (en) * | 1955-03-21 | 1957-10-30 | Schering Corp | Improvements in or relating to chemical compounds for use as x-ray diagnostic agentsand to processes for their preparation |
-
1987
- 1987-08-19 JP JP62204226A patent/JPH0788337B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB785670A (en) * | 1955-03-21 | 1957-10-30 | Schering Corp | Improvements in or relating to chemical compounds for use as x-ray diagnostic agentsand to processes for their preparation |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04303772A (en) * | 1991-03-30 | 1992-10-27 | Shimadzu Corp | Automatic analyzer for biochemistry |
Also Published As
Publication number | Publication date |
---|---|
JPH0788337B2 (en) | 1995-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |