JPS6429389A - Novel physiologically active substance and production thereof - Google Patents

Novel physiologically active substance and production thereof

Info

Publication number
JPS6429389A
JPS6429389A JP62184981A JP18498187A JPS6429389A JP S6429389 A JPS6429389 A JP S6429389A JP 62184981 A JP62184981 A JP 62184981A JP 18498187 A JP18498187 A JP 18498187A JP S6429389 A JPS6429389 A JP S6429389A
Authority
JP
Japan
Prior art keywords
tissues
variolated
molecular weight
physiologically active
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62184981A
Other languages
English (en)
Other versions
JP2651674B2 (ja
Inventor
Yoji Shibayama
Yoshio Toyomaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co Ltd filed Critical Nippon Zoki Pharmaceutical Co Ltd
Priority to JP62184981A priority Critical patent/JP2651674B2/ja
Priority to US07/221,975 priority patent/US5057324A/en
Priority to AT88810502T priority patent/ATE84721T1/de
Priority to DE8888810502T priority patent/DE3877647T2/de
Priority to EP88810502A priority patent/EP0300973B1/en
Priority to ES88810502T priority patent/ES2045182T3/es
Publication of JPS6429389A publication Critical patent/JPS6429389A/ja
Application granted granted Critical
Publication of JP2651674B2 publication Critical patent/JP2651674B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP62184981A 1987-07-23 1987-07-23 新規生理活性物質及びその製造方法 Expired - Fee Related JP2651674B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP62184981A JP2651674B2 (ja) 1987-07-23 1987-07-23 新規生理活性物質及びその製造方法
US07/221,975 US5057324A (en) 1987-07-23 1988-07-20 Kallikrein inhibitor substance, a process for preparation and pharmaceutical compositions thereof
AT88810502T ATE84721T1 (de) 1987-07-23 1988-07-21 Physiologisch wirksame produkte, verfahren zur herstellung und zusammensetzung.
DE8888810502T DE3877647T2 (de) 1987-07-23 1988-07-21 Physiologisch wirksame produkte, verfahren zur herstellung und zusammensetzung.
EP88810502A EP0300973B1 (en) 1987-07-23 1988-07-21 Physiologically active substances, a process for the preparation thereof and pharmaceutical compositions containing them
ES88810502T ES2045182T3 (es) 1987-07-23 1988-07-21 Substancias fisiologicamente activas, un proceso para la preparacion de las mismas y composiciones farmaceuticas que las contienen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62184981A JP2651674B2 (ja) 1987-07-23 1987-07-23 新規生理活性物質及びその製造方法

Publications (2)

Publication Number Publication Date
JPS6429389A true JPS6429389A (en) 1989-01-31
JP2651674B2 JP2651674B2 (ja) 1997-09-10

Family

ID=16162710

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62184981A Expired - Fee Related JP2651674B2 (ja) 1987-07-23 1987-07-23 新規生理活性物質及びその製造方法

Country Status (6)

Country Link
US (1) US5057324A (ja)
EP (1) EP0300973B1 (ja)
JP (1) JP2651674B2 (ja)
AT (1) ATE84721T1 (ja)
DE (1) DE3877647T2 (ja)
ES (1) ES2045182T3 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01230520A (ja) * 1987-11-06 1989-09-14 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985254A (en) * 1987-11-06 1991-01-15 Nippon Zoki Pharmaceutical Co., Ltd. Method of treating ischemic diseases
DE68909100T2 (de) * 1988-04-30 1994-01-13 Nippon Zoki Pharmaceutical Co Physiologisch wirkende Substanzen, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen davon.
JP2588109B2 (ja) * 1993-03-19 1997-03-05 日本臓器製薬株式会社 鎮痛剤
JP3213832B2 (ja) * 1993-08-06 2001-10-02 日本臓器製薬株式会社 被検物質の活性測定法
JP3213831B2 (ja) * 1993-08-06 2001-10-02 日本臓器製薬株式会社 被検物質の活性測定方法
JP2594222B2 (ja) * 1993-09-28 1997-03-26 日本臓器製薬株式会社 新規生理活性物質−ｋｆ
JP4033936B2 (ja) * 1997-01-08 2008-01-16 日本臓器製薬株式会社 一酸化窒素産生抑制剤
AU721804B2 (en) * 1997-01-08 2000-07-13 Nippon Zoki Pharmaceutical Co., Ltd. Nitrogen monoxide production suppressor
JPH1180005A (ja) * 1997-09-12 1999-03-23 Nippon Zoki Pharmaceut Co Ltd 骨粗鬆症治療剤
KR19990044835A (ko) 1997-11-28 1999-06-25 고니시 진우에몬 생약추출물
CN100425692C (zh) * 1998-06-02 2008-10-15 株式会社富吉摩托普拉泽兹 含有高质量生理活性的家兔发痘组织的制造方法
EP1046397A3 (en) 1999-04-15 2003-04-23 Nippon Zoki Pharmaceutical Co. Ltd. Novel bioactivating substance
US6726932B2 (en) 2000-02-18 2004-04-27 Nippon Zoki Pharmaceutical Co., Ltd. Fatty acid-containing composition
US6913900B2 (en) * 2001-08-29 2005-07-05 Nippon Zoki Pharmaceutical Co., Ltd. Plasma prekallikrein activation and kallikrein production assay
US7148012B2 (en) * 2002-10-31 2006-12-12 Nippon Zoki Pharmaceutical Co., Ltd. Therapeutic agent for fibromyalgia
CN1207005C (zh) 2002-10-31 2005-06-22 威世药业（如皋）有限公司 含生物活性物质的兔皮和其用途
KR101307999B1 (ko) * 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
US20060134646A1 (en) * 2004-12-17 2006-06-22 Ansari Aftab A Method for treatment of HIV infection
TWI483729B (zh) 2010-03-11 2015-05-11 Nippon Zoki Pharmaceutical Co 慢性前列腺炎、間質性膀胱炎及／或排尿障礙之改善或治療劑
AU2011316756B2 (en) 2010-10-14 2015-01-22 Nippon Zoki Pharmaceutical Co., Ltd A method for promoting the synthesis of collagen and proteoglycan in chondrocytes
CN115629217A (zh) 2013-04-30 2023-01-20 日本脏器制药株式会社 提取物和含有该提取物的制剂
CN105663166B (zh) * 2016-03-02 2020-04-17 中国人民解放军疾病预防控制所 特异性抗天花病毒感染模型毒株的生物活性制剂及应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5587724A (en) * 1978-12-27 1980-07-02 Nippon Zoki Pharmaceut Co Ltd Selective immune enhancer
JPS5775991A (en) * 1980-10-27 1982-05-12 Nippon Zoki Pharmaceut Co Ltd Novel physiologically active substance jcv-80
JPS5777697A (en) * 1980-11-04 1982-05-15 Nippon Zoki Pharmaceut Co Ltd Physiologically active substance nsq
JPS5835117A (ja) * 1981-08-25 1983-03-01 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質ｎｓｈ
JPS59118711A (ja) * 1982-12-25 1984-07-09 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53101515A (en) * 1977-02-17 1978-09-05 Nippon Zoki Pharmaceutical Co Medicine having anodyne * sedative and antiallergic activity and production thereof
JPS54130502A (en) * 1978-03-31 1979-10-09 Nippon Zoki Pharmaceutical Co Physiological active substance*its manufacture and medical composition
JPS5528943A (en) * 1978-08-22 1980-02-29 Nippon Zoki Pharmaceut Co Ltd Medicinal composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5587724A (en) * 1978-12-27 1980-07-02 Nippon Zoki Pharmaceut Co Ltd Selective immune enhancer
JPS5775991A (en) * 1980-10-27 1982-05-12 Nippon Zoki Pharmaceut Co Ltd Novel physiologically active substance jcv-80
JPS5777697A (en) * 1980-11-04 1982-05-15 Nippon Zoki Pharmaceut Co Ltd Physiologically active substance nsq
JPS5835117A (ja) * 1981-08-25 1983-03-01 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質ｎｓｈ
JPS59118711A (ja) * 1982-12-25 1984-07-09 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01230520A (ja) * 1987-11-06 1989-09-14 Nippon Zoki Pharmaceut Co Ltd 新規生理活性物質

Also Published As

Publication number Publication date
US5057324A (en) 1991-10-15
EP0300973B1 (en) 1993-01-20
ES2045182T3 (es) 1994-01-16
EP0300973A1 (en) 1989-01-25
ATE84721T1 (de) 1993-02-15
JP2651674B2 (ja) 1997-09-10
DE3877647T2 (de) 1993-05-13
DE3877647D1 (de) 1993-03-04

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