JPS6357103B2 - - Google Patents
Info
- Publication number
- JPS6357103B2 JPS6357103B2 JP59123242A JP12324284A JPS6357103B2 JP S6357103 B2 JPS6357103 B2 JP S6357103B2 JP 59123242 A JP59123242 A JP 59123242A JP 12324284 A JP12324284 A JP 12324284A JP S6357103 B2 JPS6357103 B2 JP S6357103B2
- Authority
- JP
- Japan
- Prior art keywords
- colloid
- ionizable
- toluamide
- diethyl
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000084 colloidal system Substances 0.000 claims description 34
- 239000003094 microcapsule Substances 0.000 claims description 33
- 239000007864 aqueous solution Substances 0.000 claims description 22
- 238000005354 coacervation Methods 0.000 claims description 18
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 claims description 17
- 239000002775 capsule Substances 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 14
- 108010010803 Gelatin Proteins 0.000 claims description 12
- 239000008273 gelatin Substances 0.000 claims description 12
- 229920000159 gelatin Polymers 0.000 claims description 12
- 235000019322 gelatine Nutrition 0.000 claims description 12
- 235000011852 gelatine desserts Nutrition 0.000 claims description 12
- 229920000084 Gum arabic Polymers 0.000 claims description 11
- 241000978776 Senegalia senegal Species 0.000 claims description 11
- 235000010489 acacia gum Nutrition 0.000 claims description 11
- 239000000205 acacia gum Substances 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- 239000004166 Lanolin Substances 0.000 claims description 9
- 230000002776 aggregation Effects 0.000 claims description 9
- 229940039717 lanolin Drugs 0.000 claims description 9
- 235000019388 lanolin Nutrition 0.000 claims description 9
- 238000005054 agglomeration Methods 0.000 claims description 7
- 239000000499 gel Substances 0.000 claims description 5
- 150000004668 long chain fatty acids Chemical class 0.000 claims description 5
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 4
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 4
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 4
- 235000010418 carrageenan Nutrition 0.000 claims description 4
- 229920001525 carrageenan Polymers 0.000 claims description 4
- 239000005018 casein Substances 0.000 claims description 4
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 4
- 235000021240 caseins Nutrition 0.000 claims description 4
- 230000001804 emulsifying effect Effects 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 239000000679 carrageenan Substances 0.000 claims description 3
- 229940113118 carrageenan Drugs 0.000 claims description 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 3
- 239000011162 core material Substances 0.000 description 15
- 239000000839 emulsion Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 239000000126 substance Substances 0.000 description 6
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 5
- 239000001263 FEMA 3042 Substances 0.000 description 5
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 5
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 5
- 229940033123 tannic acid Drugs 0.000 description 5
- 235000015523 tannic acid Nutrition 0.000 description 5
- 229920002258 tannic acid Polymers 0.000 description 5
- 238000007796 conventional method Methods 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 3
- 235000021355 Stearic acid Nutrition 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 3
- 239000008117 stearic acid Substances 0.000 description 3
- XXUNIGZDNWWYED-UHFFFAOYSA-N 2-methylbenzamide Chemical compound CC1=CC=CC=C1C(N)=O XXUNIGZDNWWYED-UHFFFAOYSA-N 0.000 description 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 2
- 238000004220 aggregation Methods 0.000 description 2
- 150000001299 aldehydes Chemical class 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001879 gelation Methods 0.000 description 2
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical compound O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 description 2
- 239000000077 insect repellent Substances 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- WGRPQCFFBRDZFV-UHFFFAOYSA-N 3-methylbenzamide Chemical compound CC1=CC=CC(C(N)=O)=C1 WGRPQCFFBRDZFV-UHFFFAOYSA-N 0.000 description 1
- ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 229910001651 emery Inorganic materials 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- -1 for example Substances 0.000 description 1
- 229940015043 glyoxal Drugs 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- SFMJNHNUOVADRW-UHFFFAOYSA-N n-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide Chemical compound C1=C(NC(=O)C=C)C(C)=CC=C1N1C(=O)C=CC2=C1C1=CC(C=3C=CC(NS(C)(=O)=O)=CC=3)=CC=C1N=C2 SFMJNHNUOVADRW-UHFFFAOYSA-N 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12324284A JPS614527A (ja) | 1984-06-14 | 1984-06-14 | 複合コアセルベーション法によるマイクロカプセルの製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12324284A JPS614527A (ja) | 1984-06-14 | 1984-06-14 | 複合コアセルベーション法によるマイクロカプセルの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS614527A JPS614527A (ja) | 1986-01-10 |
| JPS6357103B2 true JPS6357103B2 (fr) | 1988-11-10 |
Family
ID=14855718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12324284A Granted JPS614527A (ja) | 1984-06-14 | 1984-06-14 | 複合コアセルベーション法によるマイクロカプセルの製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS614527A (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2608456B1 (fr) * | 1986-12-18 | 1993-06-18 | Mero Rousselot Satia | Microcapsules a base de gelatine et de polysaccharides et leur procede d'obtention |
| JPS63192702A (ja) * | 1987-02-04 | 1988-08-10 | Toppan Moore Co Ltd | 徐放性マイクロカプセル化防虫製剤 |
| IL127396A0 (en) * | 1998-12-03 | 1999-10-28 | Univ Ben Gurion | A sustained-release polysaccharide-protein water insoluble bead and a process for preparing the same |
| US20050156340A1 (en) * | 2004-01-20 | 2005-07-21 | E Ink Corporation | Preparation of capsules |
| DE102006004526A1 (de) * | 2006-02-01 | 2007-08-02 | Lanxess Deutschland Gmbh | IPBC haltige Koazervate |
| JP6106421B2 (ja) * | 2012-12-14 | 2017-03-29 | ライオン株式会社 | カプセル、毛髪用液体洗浄剤組成物およびそれらの製造方法 |
| JP6414443B2 (ja) * | 2014-10-31 | 2018-10-31 | ユーハ味覚糖株式会社 | 天然物由来成分を基材とするナノ粒子 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS537396A (en) * | 1976-07-09 | 1978-01-23 | Kyowa Hakko Kogyo Kk | Determination of sphingomyelin |
| JPS5844079A (ja) * | 1981-09-09 | 1983-03-14 | 高橋 均 | 歩行ロボツト |
-
1984
- 1984-06-14 JP JP12324284A patent/JPS614527A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS537396A (en) * | 1976-07-09 | 1978-01-23 | Kyowa Hakko Kogyo Kk | Determination of sphingomyelin |
| JPS5844079A (ja) * | 1981-09-09 | 1983-03-14 | 高橋 均 | 歩行ロボツト |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS614527A (ja) | 1986-01-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4808408A (en) | Microcapsules prepared by coacervation | |
| US3043782A (en) | Process for preparing a more impermeable coating by liquid-liquid phase separation | |
| US3539465A (en) | Encapsulation of hydrophilic liquid-in-oil emulsions | |
| US5023024A (en) | Process for producing microcapsules | |
| JPS63197540A (ja) | ゼラチン・多糖類マイクロカプセルとその製法 | |
| AU588275B2 (en) | Encapsulating compound with solvent-dependent solubility | |
| JP2550305B2 (ja) | 小粒子の形成およびカプセル化 | |
| EP0768870B1 (fr) | Encapsulation multiple de substances oleophiles | |
| US20080277812A1 (en) | Wax Encapsulation | |
| JP5931859B2 (ja) | 固形コアコアセルベート化したカプセル | |
| EP1371410A1 (fr) | Coacérvates complexes contenant de protéines au petit-lait | |
| JPS5812055B2 (ja) | 疎水性油滴含有カプセルの硬化方法 | |
| US3549555A (en) | Encapsulation of lipophilic liquid-in-hydrophilic liquid emulsions | |
| JPS6357103B2 (fr) | ||
| US3328257A (en) | Preparation of microcapsules | |
| EP0126583B1 (fr) | Procédé de micro-encapsulation par coacervation et les microcapsules préparées ainsi | |
| JP2617107B2 (ja) | 耐熱性マイクロカプセルの製造方法 | |
| WO2006091081A1 (fr) | Microcapsules | |
| CA1330941C (fr) | Composition a liberation prolongee, a base de reactifs sous forme de sels, et methode pour sa fabrication | |
| JPH057766A (ja) | マイクロカプセルの製造方法 | |
| JPH01148338A (ja) | マイクロカプセルの製造法 | |
| JP3179877B2 (ja) | ゼラチン・中性多糖類マイクロカプセル及びその製法 | |
| JP2000159661A (ja) | 徐放性マイクロカプセル含有水性組成物 | |
| US4217241A (en) | Process for the microcapsulation of organophosphoric acid derivative-containing agricultural chemicals | |
| JPH0726251A (ja) | 蓄熱用マイクロカプセルおよびその製造方法 |