JPS632277B2 - - Google Patents

Info

Publication number
JPS632277B2
JPS632277B2 JP55112102A JP11210280A JPS632277B2 JP S632277 B2 JPS632277 B2 JP S632277B2 JP 55112102 A JP55112102 A JP 55112102A JP 11210280 A JP11210280 A JP 11210280A JP S632277 B2 JPS632277 B2 JP S632277B2
Authority
JP
Japan
Prior art keywords
deoxyfluorouridine
ester derivative
fluorouridine
deoxy
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55112102A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5735596A (en
Inventor
Setsuo Fujii
Bonpei Yasui
Mitsuo Nakamura
Tomohisa Myamoto
Kazuko Ando
Iwao Hashimoto
Yoneichi Sawai
Naoki Umeda
Masahiro Kawasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Funai Pharmaceutical Industries Ltd
Original Assignee
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Funai Pharmaceutical Industries Ltd filed Critical Funai Pharmaceutical Industries Ltd
Priority to JP11210280A priority Critical patent/JPS5735596A/ja
Priority to GB8104375A priority patent/GB2072164B/en
Priority to DE19813105111 priority patent/DE3105111A1/de
Priority to CH96481A priority patent/CH646715A5/de
Priority to ES499443A priority patent/ES8206550A1/es
Priority to FR8102922A priority patent/FR2476086A1/fr
Priority to AT0069181A priority patent/AT374203B/de
Priority to IT8119758A priority patent/IT1210989B/it
Priority to US06/290,420 priority patent/US4416875A/en
Priority to CA000383525A priority patent/CA1175815A/en
Priority to PH26030A priority patent/PH18174A/en
Publication of JPS5735596A publication Critical patent/JPS5735596A/ja
Publication of JPS632277B2 publication Critical patent/JPS632277B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP11210280A 1980-02-15 1980-08-13 Ester derivative of deoxyfluorouridine Granted JPS5735596A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP11210280A JPS5735596A (en) 1980-08-13 1980-08-13 Ester derivative of deoxyfluorouridine
GB8104375A GB2072164B (en) 1980-02-15 1981-02-12 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives
DE19813105111 DE3105111A1 (de) 1980-02-15 1981-02-12 "2 -desoxy-3',5-di-o-alkylcarbonyl-5-fluoruridin-derivate, verfahren zu ihrer herstellung, ihre verwendung zur behandlung von tumoren und antitumormittel"
CH96481A CH646715A5 (de) 1980-02-15 1981-02-13 2'-desoxy-3',5'-di-o-alkylcarbonyl-5-fluoruridin-derivate, verfahren zu ihrer herstellung und antitumormittel.
ES499443A ES8206550A1 (es) 1980-02-15 1981-02-13 Un procedimiento para la preparacion de derivados de 2-desoxi-3-5-di-o-alquilcarbonil-5-fluorurina.
FR8102922A FR2476086A1 (fr) 1980-02-15 1981-02-13 2'-desoxy-3',5'-di-o-alkylcarbonyl-5-fluoro-uridines, leur preparation et leur utilisation therapeutique en tant qu'agents anti-tumeurs
AT0069181A AT374203B (de) 1980-02-15 1981-02-13 Verfahren zur herstellung von neuen 2'-desoxy-3', 5'-di-o-alkylcarbonyl-5-fluoruridinderivaten
IT8119758A IT1210989B (it) 1980-02-15 1981-02-13 Derivati 2'-deossi-3',5'-di-o-alchilcarbonil-5-fluorouri dinici processo per la loro preparazione e agenti antitumorali che contengono i detti derivati.
US06/290,420 US4416875A (en) 1980-08-13 1981-08-06 Ester derivatives of deoxyfluorouridine
CA000383525A CA1175815A (en) 1980-08-13 1981-08-10 Ester derivatives of deoxyfluorouridine
PH26030A PH18174A (en) 1980-08-13 1981-08-11 Ester derivatives of deoxyflourouridine,their process of preparation and pharmaceutical composition containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11210280A JPS5735596A (en) 1980-08-13 1980-08-13 Ester derivative of deoxyfluorouridine

Publications (2)

Publication Number Publication Date
JPS5735596A JPS5735596A (en) 1982-02-26
JPS632277B2 true JPS632277B2 (OSRAM) 1988-01-18

Family

ID=14578176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11210280A Granted JPS5735596A (en) 1980-02-15 1980-08-13 Ester derivative of deoxyfluorouridine

Country Status (4)

Country Link
US (1) US4416875A (OSRAM)
JP (1) JPS5735596A (OSRAM)
CA (1) CA1175815A (OSRAM)
PH (1) PH18174A (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5896024A (ja) * 1981-10-16 1983-06-07 リチヤ−ド・エフ・ストツケル 白金毒解毒剤
SG48855A1 (en) * 1992-04-20 1998-05-18 Takeda Chemical Industries Ltd 4,1-benzoxazepin derivatives and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853845A (en) * 1971-08-18 1974-12-10 Icn Pharmaceuticals 5-n-aminoacyl-5-aminouridines
JPS5924999B2 (ja) * 1978-06-10 1984-06-13 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体の製造法
JPS56115799A (en) * 1980-02-15 1981-09-11 Funai Corp 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivative, its preparation, and antitumor agnet containing the same

Also Published As

Publication number Publication date
US4416875A (en) 1983-11-22
JPS5735596A (en) 1982-02-26
CA1175815A (en) 1984-10-09
PH18174A (en) 1985-04-12

Similar Documents

Publication Publication Date Title
Sterzycki et al. Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides
EP0717748B1 (fr) Composes 2' ou 3'-deoxy- et 2', 3'-dideoxy-beta-l-pentofuranonucleosides, procede de preparation et application therapeutique, notamment anti-virale
PT1989214T (pt) Processo para preparar um agonista de recetor de adenosina a2a e polimorfos do mesmo
JPH0637394B2 (ja) 腫瘍治療剤
JPS6299395A (ja) ２−アルキニルアデノシンおよび抗高血圧剤
JP2873086B2 (ja) 複素環化合物
US4490366A (en) 2'-Deoxy-5-fluorouridine derivative and a process for producing the same and an antitumor agent comprising the same
KR860001865B1 (ko) 2'-데옥시-5-치환 우리딘 유도체의 제조방법
JP2017057200A (ja) 抗ｄｎａウィルス活性などの生理活性を有するヌクレオシド誘導体
US4503045A (en) 2'-Deoxy-3',5'-di-O-alkylcarbonyl-5-fluorouridine derivatives, a process for the preparation of the derivatives and anti-tumor agents containing the derivatives
HU204841B (en) Process for producing medicinal nucleosides and pharmaceutical compositions comprising same
JPS632277B2 (OSRAM)
JPS632279B2 (OSRAM)
JPH0340034B2 (OSRAM)
WO1992019638A1 (fr) DERIVE DE 1-β-D-ARABINOFURANOSYL-(E)-5-(2-HALOGENOVINYL)-URACILE
JPS6312477B2 (OSRAM)
JPH0340038B2 (OSRAM)
JPH0340039B2 (OSRAM)
JPH0340037B2 (OSRAM)
GB2072164A (en) 2%-Deoxy-3%,5%-di-O- alkylcarbonyl-5-fluorouridine derivatives, a process for the preparation of the derivatives and anti-tumor agents containing the derivatives
KR860001867B1 (ko) 2'-데옥시-5-치환 우리딘 유도체의 제조방법
JP7125714B2 (ja) 抗ウイルス活性を有する２’－デオキシ－７－デアザプリンヌクレオシド誘導体
US5250673A (en) 2'-deoxy-5-substituted uridine derivatives
JPH0340036B2 (OSRAM)
JPS644520B2 (OSRAM)