JPS6318457B2 - - Google Patents
Info
- Publication number
- JPS6318457B2 JPS6318457B2 JP58247219A JP24721983A JPS6318457B2 JP S6318457 B2 JPS6318457 B2 JP S6318457B2 JP 58247219 A JP58247219 A JP 58247219A JP 24721983 A JP24721983 A JP 24721983A JP S6318457 B2 JPS6318457 B2 JP S6318457B2
- Authority
- JP
- Japan
- Prior art keywords
- bifidobacterium
- milk
- gal
- enzyme
- galactosidase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000186000 Bifidobacterium Species 0.000 claims description 27
- 102000004190 Enzymes Human genes 0.000 claims description 25
- 108090000790 Enzymes Proteins 0.000 claims description 25
- 108010005774 beta-Galactosidase Proteins 0.000 claims description 22
- 102000005936 beta-Galactosidase Human genes 0.000 claims description 21
- 235000013336 milk Nutrition 0.000 claims description 15
- 210000004080 milk Anatomy 0.000 claims description 15
- 239000008267 milk Substances 0.000 claims description 14
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 240000006439 Aspergillus oryzae Species 0.000 claims description 10
- 235000002247 Aspergillus oryzae Nutrition 0.000 claims description 10
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 9
- 239000008101 lactose Substances 0.000 claims description 9
- 235000013305 food Nutrition 0.000 claims description 8
- 230000001737 promoting effect Effects 0.000 claims description 6
- 238000012258 culturing Methods 0.000 claims description 4
- 239000007858 starting material Substances 0.000 claims description 4
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 229940088598 enzyme Drugs 0.000 description 24
- 229920001542 oligosaccharide Polymers 0.000 description 24
- 150000002482 oligosaccharides Chemical class 0.000 description 24
- 239000003102 growth factor Substances 0.000 description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 238000001727 in vivo Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000011541 reaction mixture Substances 0.000 description 5
- 230000035484 reaction time Effects 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 210000000936 intestine Anatomy 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 241000186012 Bifidobacterium breve Species 0.000 description 3
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical group OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 3
- 150000002016 disaccharides Chemical class 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 150000002772 monosaccharides Chemical class 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 150000004044 tetrasaccharides Chemical class 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 150000004043 trisaccharides Chemical group 0.000 description 3
- 102000002464 Galactosidases Human genes 0.000 description 2
- 108010093031 Galactosidases Proteins 0.000 description 2
- 244000018633 Prunus armeniaca Species 0.000 description 2
- 235000009827 Prunus armeniaca Nutrition 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000015140 cultured milk Nutrition 0.000 description 2
- 238000006911 enzymatic reaction Methods 0.000 description 2
- 235000003599 food sweetener Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 239000007952 growth promoter Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 235000008476 powdered milk Nutrition 0.000 description 2
- 238000006462 rearrangement reaction Methods 0.000 description 2
- 235000020183 skimmed milk Nutrition 0.000 description 2
- 239000003765 sweetening agent Substances 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 102100026189 Beta-galactosidase Human genes 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 108010059881 Lactase Proteins 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 229940116108 lactase Drugs 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 235000020124 milk-based beverage Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 235000020122 reconstituted milk Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000006276 transfer reaction Methods 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dairy Products (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58247219A JPS6041449A (ja) | 1983-12-26 | 1983-12-26 | ビフイドバクテリウム菌増殖促進因子を含有する飲食物の製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58247219A JPS6041449A (ja) | 1983-12-26 | 1983-12-26 | ビフイドバクテリウム菌増殖促進因子を含有する飲食物の製造法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1283779A Division JPS5820266B2 (ja) | 1979-02-08 | 1979-02-08 | ビフィドバクテリウム菌の増殖促進性組成物及びその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6041449A JPS6041449A (ja) | 1985-03-05 |
| JPS6318457B2 true JPS6318457B2 (ko) | 1988-04-19 |
Family
ID=17160216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58247219A Granted JPS6041449A (ja) | 1983-12-26 | 1983-12-26 | ビフイドバクテリウム菌増殖促進因子を含有する飲食物の製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6041449A (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2518663B2 (ja) * | 1987-12-24 | 1996-07-24 | 株式会社ヤクルト本社 | ガラクトオリゴ糖含有加工乳の製造法 |
| JPH11116484A (ja) * | 1997-10-09 | 1999-04-27 | Yakult Honsha Co Ltd | 炎症性腸疾患予防・治療剤及び飲食品 |
| ES2331827B1 (es) * | 2008-02-05 | 2010-10-26 | Consejo Superior De Investigaciones Cientificas | Procedimiento de elaboracion de leches fermentadas con elevado contenido en oligosacaridos prebioticos, leche fermentada asi obtenida. |
| KR102534934B1 (ko) * | 2015-06-01 | 2023-05-19 | 사이세이 파마 씨오., 엘티디. | 우유 효소 처리물, 그 제조 방법, 조성물 및 제품 |
-
1983
- 1983-12-26 JP JP58247219A patent/JPS6041449A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6041449A (ja) | 1985-03-05 |
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