JPS63118654A - 多項目イムノアツセイ装置 - Google Patents
多項目イムノアツセイ装置Info
- Publication number
- JPS63118654A JPS63118654A JP26405786A JP26405786A JPS63118654A JP S63118654 A JPS63118654 A JP S63118654A JP 26405786 A JP26405786 A JP 26405786A JP 26405786 A JP26405786 A JP 26405786A JP S63118654 A JPS63118654 A JP S63118654A
- Authority
- JP
- Japan
- Prior art keywords
- sample
- antibodies
- columns
- measured
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003018 immunoassay Methods 0.000 title claims description 10
- 239000000427 antigen Substances 0.000 claims abstract description 8
- 102000036639 antigens Human genes 0.000 claims abstract description 8
- 108091007433 antigens Proteins 0.000 claims abstract description 8
- 239000007790 solid phase Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims description 13
- 239000011521 glass Substances 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims 1
- 229920000620 organic polymer Polymers 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 abstract description 28
- 239000007788 liquid Substances 0.000 abstract description 20
- 238000005259 measurement Methods 0.000 abstract description 15
- 238000002347 injection Methods 0.000 abstract description 6
- 239000007924 injection Substances 0.000 abstract description 6
- 239000000203 mixture Substances 0.000 abstract description 5
- 238000001514 detection method Methods 0.000 abstract description 4
- 108010015776 Glucose oxidase Proteins 0.000 abstract description 2
- 239000004366 Glucose oxidase Substances 0.000 abstract description 2
- 229940116332 glucose oxidase Drugs 0.000 abstract description 2
- 235000019420 glucose oxidase Nutrition 0.000 abstract description 2
- 238000002372 labelling Methods 0.000 abstract description 2
- 230000021615 conjugation Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 18
- 206010028980 Neoplasm Diseases 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 238000000034 method Methods 0.000 description 7
- 239000007853 buffer solution Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 102100023635 Alpha-fetoprotein Human genes 0.000 description 5
- 238000003556 assay Methods 0.000 description 5
- 201000011510 cancer Diseases 0.000 description 5
- 102000015736 beta 2-Microglobulin Human genes 0.000 description 4
- 108010081355 beta 2-Microglobulin Proteins 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000008363 phosphate buffer Substances 0.000 description 3
- 239000000439 tumor marker Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000007667 floating Methods 0.000 description 2
- 239000011491 glass wool Substances 0.000 description 2
- QRMZSPFSDQBLIX-UHFFFAOYSA-N homovanillic acid Chemical compound COC1=CC(CC(O)=O)=CC=C1O QRMZSPFSDQBLIX-UHFFFAOYSA-N 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 229910000077 silane Inorganic materials 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 description 1
- SJECZPVISLOESU-UHFFFAOYSA-N 3-trimethoxysilylpropan-1-amine Chemical compound CO[Si](OC)(OC)CCCN SJECZPVISLOESU-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 235000010582 Pisum sativum Nutrition 0.000 description 1
- 240000004713 Pisum sativum Species 0.000 description 1
- 238000011481 absorbance measurement Methods 0.000 description 1
- 125000003172 aldehyde group Chemical group 0.000 description 1
- 108010026331 alpha-Fetoproteins Proteins 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26405786A JPS63118654A (ja) | 1986-11-07 | 1986-11-07 | 多項目イムノアツセイ装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26405786A JPS63118654A (ja) | 1986-11-07 | 1986-11-07 | 多項目イムノアツセイ装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63118654A true JPS63118654A (ja) | 1988-05-23 |
| JPH0588786B2 JPH0588786B2 (cg-RX-API-DMAC7.html) | 1993-12-24 |
Family
ID=17397940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP26405786A Granted JPS63118654A (ja) | 1986-11-07 | 1986-11-07 | 多項目イムノアツセイ装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63118654A (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007163163A (ja) * | 2005-12-09 | 2007-06-28 | Sharp Corp | バイオケミカルセンサ及び測定装置 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4722977B2 (ja) * | 2008-08-27 | 2011-07-13 | シャープ株式会社 | 検出器具、分析装置、検出方法および検出器具の制御方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51123891A (en) * | 1975-04-18 | 1976-10-28 | Kuraray Co Ltd | Process for producing protein microbiologically |
| JPS5712363A (en) * | 1980-06-24 | 1982-01-22 | Daiichi Rajio Isotope Kenkyusho:Kk | Immunoassay for various simultaneous measurement |
| JPS6089753A (ja) * | 1983-03-17 | 1985-05-20 | マスト イミユノシステムズ リミテツド | 結合試験用器具，その製方及び用法 |
| JPS60104260A (ja) * | 1983-08-26 | 1985-06-08 | ザ リ−ジエンツ オブ ザ ユニバ−シテイ オブ カリフオルニア | マイクロアツセイロツド |
| JPS61219863A (ja) * | 1985-03-26 | 1986-09-30 | Yamasa Shoyu Co Ltd | 多項目同時イムノアツセイおよびその試薬 |
-
1986
- 1986-11-07 JP JP26405786A patent/JPS63118654A/ja active Granted
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51123891A (en) * | 1975-04-18 | 1976-10-28 | Kuraray Co Ltd | Process for producing protein microbiologically |
| JPS5712363A (en) * | 1980-06-24 | 1982-01-22 | Daiichi Rajio Isotope Kenkyusho:Kk | Immunoassay for various simultaneous measurement |
| JPS6089753A (ja) * | 1983-03-17 | 1985-05-20 | マスト イミユノシステムズ リミテツド | 結合試験用器具，その製方及び用法 |
| JPS60104260A (ja) * | 1983-08-26 | 1985-06-08 | ザ リ−ジエンツ オブ ザ ユニバ−シテイ オブ カリフオルニア | マイクロアツセイロツド |
| JPS61219863A (ja) * | 1985-03-26 | 1986-09-30 | Yamasa Shoyu Co Ltd | 多項目同時イムノアツセイおよびその試薬 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007163163A (ja) * | 2005-12-09 | 2007-06-28 | Sharp Corp | バイオケミカルセンサ及び測定装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0588786B2 (cg-RX-API-DMAC7.html) | 1993-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |