JPS626687B2 - - Google Patents
Info
- Publication number
- JPS626687B2 JPS626687B2 JP54170613A JP17061379A JPS626687B2 JP S626687 B2 JPS626687 B2 JP S626687B2 JP 54170613 A JP54170613 A JP 54170613A JP 17061379 A JP17061379 A JP 17061379A JP S626687 B2 JPS626687 B2 JP S626687B2
- Authority
- JP
- Japan
- Prior art keywords
- extracts
- astragalus
- peripheral
- crude drug
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 claims description 42
- 229940079593 drug Drugs 0.000 claims description 41
- 239000000284 extract Substances 0.000 claims description 32
- 241001061264 Astragalus Species 0.000 claims description 16
- 235000006533 astragalus Nutrition 0.000 claims description 16
- 210000004233 talus Anatomy 0.000 claims description 16
- 230000003836 peripheral circulation Effects 0.000 claims description 13
- 244000020518 Carthamus tinctorius Species 0.000 claims description 12
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 11
- WTPPRJKFRFIQKT-UHFFFAOYSA-N 1,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione;1-methyl-6-methylidene-8,9-dihydro-7h-naphtho[1,2-g][1]benzofuran-10,11-dione Chemical compound O=C1C(=O)C2=C3CCCC(=C)C3=CC=C2C2=C1C(C)=CO2.O=C1C(=O)C2=C3CCC=C(C)C3=CC=C2C2=C1C(C)=CO2 WTPPRJKFRFIQKT-UHFFFAOYSA-N 0.000 claims description 8
- 244000132619 red sage Species 0.000 claims description 8
- 235000008434 ginseng Nutrition 0.000 claims description 5
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 4
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 4
- 240000004371 Panax ginseng Species 0.000 claims description 3
- 235000002789 Panax ginseng Nutrition 0.000 claims description 2
- 244000236658 Paeonia lactiflora Species 0.000 claims 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 claims 1
- 241000411851 herbal medicine Species 0.000 description 14
- 230000002093 peripheral effect Effects 0.000 description 11
- 239000000203 mixture Substances 0.000 description 8
- 230000000304 vasodilatating effect Effects 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 6
- 241000736199 Paeonia Species 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 241000208340 Araliaceae Species 0.000 description 3
- 206010065929 Cardiovascular insufficiency Diseases 0.000 description 3
- 235000006484 Paeonia officinalis Nutrition 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 210000001105 femoral artery Anatomy 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000012488 sample solution Substances 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- UNPLRYRWJLTVAE-UHFFFAOYSA-N Cloperastine hydrochloride Chemical compound Cl.C1=CC(Cl)=CC=C1C(C=1C=CC=CC=1)OCCN1CCCCC1 UNPLRYRWJLTVAE-UHFFFAOYSA-N 0.000 description 2
- 239000004129 EU approved improving agent Substances 0.000 description 2
- 208000001034 Frostbite Diseases 0.000 description 2
- 208000003782 Raynaud disease Diseases 0.000 description 2
- 208000012322 Raynaud phenomenon Diseases 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000000469 ethanolic extract Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 229940124549 vasodilator Drugs 0.000 description 2
- 239000003071 vasodilator agent Substances 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- UKUVVAMSXXBMRX-UHFFFAOYSA-N 2,4,5-trithia-1,3-diarsabicyclo[1.1.1]pentane Chemical compound S1[As]2S[As]1S2 UKUVVAMSXXBMRX-UHFFFAOYSA-N 0.000 description 1
- 206010003178 Arterial thrombosis Diseases 0.000 description 1
- 208000000575 Arteriosclerosis Obliterans Diseases 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 description 1
- 241001121987 Scrophularia ningpoensis Species 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000003218 coronary vasodilator agent Substances 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000002464 muscle smooth vascular Anatomy 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000006201 parenteral dosage form Substances 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000036581 peripheral resistance Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002820 sympathetic nervous system Anatomy 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000005526 vasoconstrictor agent Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17061379A JPS5692216A (en) | 1979-12-27 | 1979-12-27 | Peripheral circulation improver containing crude drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17061379A JPS5692216A (en) | 1979-12-27 | 1979-12-27 | Peripheral circulation improver containing crude drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5692216A JPS5692216A (en) | 1981-07-25 |
| JPS626687B2 true JPS626687B2 (de) | 1987-02-13 |
Family
ID=15908099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17061379A Granted JPS5692216A (en) | 1979-12-27 | 1979-12-27 | Peripheral circulation improver containing crude drug |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5692216A (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9104286D0 (en) * | 1991-02-28 | 1991-04-17 | Phytopharm Ltd | Pharmaceutical compositions for the treatment of skin disorders |
| KR100341674B1 (ko) * | 1998-09-25 | 2002-10-25 | 강희송 | 홍화엑기스추출방법및동방법에의해제조되는홍화엑기스 |
| JP4797030B2 (ja) * | 2008-02-04 | 2011-10-19 | 有限会社 本町薬品 | 血栓溶解剤の製造方法 |
| CN102716367A (zh) * | 2012-06-21 | 2012-10-10 | 浙江满堂花生物科技有限公司 | 一种复方铁皮石斛含片及其制备方法 |
| JPWO2014104162A1 (ja) * | 2012-12-26 | 2017-01-12 | 興和株式会社 | 医薬 |
| CN103070943B (zh) * | 2013-01-28 | 2015-05-13 | 西北农林科技大学 | 一种治疗心脑血管疾病的中药及其制备方法 |
| CN104713979B (zh) * | 2014-09-23 | 2016-08-31 | 上海中医药大学 | 一种铁皮石斛的薄层鉴别方法 |
| CN105424850B (zh) * | 2015-11-05 | 2017-08-29 | 北京蓝标一成科技有限公司 | 一种石斛药材的检测方法 |
| CN107029008A (zh) * | 2017-06-16 | 2017-08-11 | 佳木斯大学附属第医院 | 一种治疗心衰的药物及其制备方法和应用 |
-
1979
- 1979-12-27 JP JP17061379A patent/JPS5692216A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5692216A (en) | 1981-07-25 |
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