JPS6257186B2 - - Google Patents

Info

Publication number
JPS6257186B2
JPS6257186B2 JP55102410A JP10241080A JPS6257186B2 JP S6257186 B2 JPS6257186 B2 JP S6257186B2 JP 55102410 A JP55102410 A JP 55102410A JP 10241080 A JP10241080 A JP 10241080A JP S6257186 B2 JPS6257186 B2 JP S6257186B2
Authority
JP
Japan
Prior art keywords
carboxymethyl
compound according
group
rhodanine
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55102410A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5728074A (en
Inventor
Tadao Tauchi
Tooru Shigeoka
Masanori Kawamura
Masaki Hayashi
Hiroshi Terajima
Fumio Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP10241080A priority Critical patent/JPS5728074A/ja
Priority to EP81303308A priority patent/EP0045165B1/en
Priority to DE8181303308T priority patent/DE3174053D1/de
Priority to US06/286,839 priority patent/US4446143A/en
Publication of JPS5728074A publication Critical patent/JPS5728074A/ja
Publication of JPS6257186B2 publication Critical patent/JPS6257186B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP10241080A 1980-07-28 1980-07-28 Rhodanine derivative, its preparation, and inhibitor for aldose reducing enzyme consisting essentially of it Granted JPS5728074A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP10241080A JPS5728074A (en) 1980-07-28 1980-07-28 Rhodanine derivative, its preparation, and inhibitor for aldose reducing enzyme consisting essentially of it
EP81303308A EP0045165B1 (en) 1980-07-28 1981-07-20 Rhodanine derivatives, a process for their preparation, and aldose reductase inhibitors containing such derivatives
DE8181303308T DE3174053D1 (en) 1980-07-28 1981-07-20 Rhodanine derivatives, a process for their preparation, and aldose reductase inhibitors containing such derivatives
US06/286,839 US4446143A (en) 1980-07-28 1981-07-27 Rhodanine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10241080A JPS5728074A (en) 1980-07-28 1980-07-28 Rhodanine derivative, its preparation, and inhibitor for aldose reducing enzyme consisting essentially of it

Publications (2)

Publication Number Publication Date
JPS5728074A JPS5728074A (en) 1982-02-15
JPS6257186B2 true JPS6257186B2 (https=) 1987-11-30

Family

ID=14326663

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10241080A Granted JPS5728074A (en) 1980-07-28 1980-07-28 Rhodanine derivative, its preparation, and inhibitor for aldose reducing enzyme consisting essentially of it

Country Status (4)

Country Link
US (1) US4446143A (https=)
EP (1) EP0045165B1 (https=)
JP (1) JPS5728074A (https=)
DE (1) DE3174053D1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6153271A (ja) * 1984-08-24 1986-03-17 Kaken Pharmaceut Co Ltd ローダニン誘導体
JPS60136575A (ja) * 1983-11-29 1985-07-20 Kaken Pharmaceut Co Ltd ロ−ダニン誘導体およびその製造法
ES537999A0 (es) * 1983-11-29 1985-12-01 Kaken Pharma Co Ltd Un procedimiento para preparar un derivado de rodanina
JPS6212776A (ja) 1985-07-10 1987-01-21 Taiho Yakuhin Kogyo Kk ロ−ダニン誘導体
AU1558288A (en) * 1987-05-11 1988-11-17 Kaken Pharmaceutical Co., Ltd. Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same
US5116855A (en) * 1989-05-19 1992-05-26 Nisshin Flour Milling Co., Ltd. Rhodanine derivatives and pharmaceutical compositions
NZ248573A (en) * 1992-09-10 1996-02-27 Lilly Co Eli 5-arylmethyl (and methylidene) thiazolidin-4-one derivatives; their preparation and pharmaceutical compositions
US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US6673816B1 (en) 1998-09-30 2004-01-06 Angelika Esswein Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
AU2001258854A1 (en) * 2000-06-07 2001-12-17 Senju Pharmaceutical Co. Ltd. Novel thiazolidinedione derivatives and use thereof as drugs
CN105949100B (zh) * 2016-05-18 2017-12-19 浙江云涛生物技术股份有限公司 新型二硫代氨基甲酸盐类重金属螯合剂的生产工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU173774A (https=) *
SU173773A (https=) *
CH526257A (de) * 1970-02-02 1972-08-15 Ciba Geigy Ag Verwendung von N-Arylrhodaninen zur Bekämpfung von Vertretern der Ordnung Akarina
JPS5953532B2 (ja) * 1978-08-05 1984-12-25 三菱製紙株式会社 ハロゲン化銀写真感光材料
JPS56111849A (en) * 1980-02-12 1981-09-03 Konishiroku Photo Ind Co Ltd Silver halide photographic sensitive material

Also Published As

Publication number Publication date
JPS5728074A (en) 1982-02-15
EP0045165A1 (en) 1982-02-03
EP0045165B1 (en) 1986-03-12
DE3174053D1 (en) 1986-04-17
US4446143A (en) 1984-05-01

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