JPS6243696B2 - - Google Patents

Info

Publication number

JPS6243696B2

JPS6243696B2 JP52059934A JP5993477A JPS6243696B2 JP S6243696 B2 JPS6243696 B2 JP S6243696B2 JP 52059934 A JP52059934 A JP 52059934A JP 5993477 A JP5993477 A JP 5993477A JP S6243696 B2 JPS6243696 B2 JP S6243696B2

Authority

JP

Japan

Prior art keywords

adsorbent

blood

activated carbon

ethyl cellulose

coated

Prior art date

1977-05-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Links

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• 229920001249 ethyl cellulose Polymers 0.000 claims description 32
• 235000019325 ethyl cellulose Nutrition 0.000 claims description 32
• 239000001856 Ethyl cellulose Substances 0.000 claims description 31
• ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 31
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
• OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 29
• 210000000056 organ Anatomy 0.000 claims description 26
• YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 18
• 239000002245 particle Substances 0.000 claims description 9
• 239000012046 mixed solvent Substances 0.000 claims description 7
• 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 5
• 239000011301 petroleum pitch Substances 0.000 claims 1
• 239000003463 adsorbent Substances 0.000 description 38
• 239000008280 blood Substances 0.000 description 19
• 210000004369 blood Anatomy 0.000 description 19
• 238000001179 sorption measurement Methods 0.000 description 13
• 238000000034 method Methods 0.000 description 11
• 235000019441 ethanol Nutrition 0.000 description 10
• 239000003610 charcoal Substances 0.000 description 9
• 239000000243 solution Substances 0.000 description 8
• 238000002474 experimental method Methods 0.000 description 7
• DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 6
• 239000002699 waste material Substances 0.000 description 6
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
• 230000023555 blood coagulation Effects 0.000 description 5
• 239000000428 dust Substances 0.000 description 5
• 231100000614 poison Toxicity 0.000 description 5
• 239000002904 solvent Substances 0.000 description 5
• 230000001954 sterilising effect Effects 0.000 description 5
• 239000003440 toxic substance Substances 0.000 description 5
• 210000003734 kidney Anatomy 0.000 description 4
• 239000002994 raw material Substances 0.000 description 4
• 238000004659 sterilization and disinfection Methods 0.000 description 4
• 239000010409 thin film Substances 0.000 description 4
• 239000000020 Nitrocellulose Substances 0.000 description 3
• 238000000576 coating method Methods 0.000 description 3
• 230000000052 comparative effect Effects 0.000 description 3
• 229940109239 creatinine Drugs 0.000 description 3
• 238000001035 drying Methods 0.000 description 3
• 239000000463 material Substances 0.000 description 3
• 229920001220 nitrocellulos Polymers 0.000 description 3
• 239000007787 solid Substances 0.000 description 3
• 238000005507 spraying Methods 0.000 description 3
• 102000009027 Albumins Human genes 0.000 description 2
• 108010088751 Albumins Proteins 0.000 description 2
• 230000008081 blood perfusion Effects 0.000 description 2
• 239000011248 coating agent Substances 0.000 description 2
• 239000012153 distilled water Substances 0.000 description 2
• 238000005516 engineering process Methods 0.000 description 2
• 210000004185 liver Anatomy 0.000 description 2
• 238000004519 manufacturing process Methods 0.000 description 2
• 239000003208 petroleum Substances 0.000 description 2
• 239000002504 physiological saline solution Substances 0.000 description 2
• 238000006116 polymerization reaction Methods 0.000 description 2
• 230000001629 suppression Effects 0.000 description 2
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
• PPWHTZKZQNXVAE-UHFFFAOYSA-N Tetracaine hydrochloride Chemical compound Cl.CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 PPWHTZKZQNXVAE-UHFFFAOYSA-N 0.000 description 1
• LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
• TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
• 239000003513 alkali Substances 0.000 description 1
• 239000003146 anticoagulant agent Substances 0.000 description 1
• 229940127219 anticoagulant drug Drugs 0.000 description 1
• 239000007864 aqueous solution Substances 0.000 description 1
• 238000009835 boiling Methods 0.000 description 1
• 244000144987 brood Species 0.000 description 1
• 229910052799 carbon Inorganic materials 0.000 description 1
• 229920002678 cellulose Polymers 0.000 description 1
• 239000001913 cellulose Substances 0.000 description 1
• 239000003795 chemical substances by application Substances 0.000 description 1
• 239000002817 coal dust Substances 0.000 description 1
• FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 description 1
• 239000003431 cross linking reagent Substances 0.000 description 1
• YPHMISFOHDHNIV-FSZOTQKASA-N cycloheximide Chemical compound C1[C@@H](C)C[C@H](C)C(=O)[C@@H]1[C@H](O)CC1CC(=O)NC(=O)C1 YPHMISFOHDHNIV-FSZOTQKASA-N 0.000 description 1
• 238000000354 decomposition reaction Methods 0.000 description 1
• 201000010099 disease Diseases 0.000 description 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
• 239000008298 dragée Substances 0.000 description 1
• NJSUFZNXBBXAAC-UHFFFAOYSA-N ethanol;toluene Chemical compound CCO.CC1=CC=CC=C1 NJSUFZNXBBXAAC-UHFFFAOYSA-N 0.000 description 1
• 238000001704 evaporation Methods 0.000 description 1
• 239000010408 film Substances 0.000 description 1
• 238000007667 floating Methods 0.000 description 1
• 239000007788 liquid Substances 0.000 description 1
• 239000003094 microcapsule Substances 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
• 229920000642 polymer Polymers 0.000 description 1
• 239000002861 polymer material Substances 0.000 description 1
• 229920001296 polysiloxane Polymers 0.000 description 1
• 239000000843 powder Substances 0.000 description 1
• 239000000126 substance Substances 0.000 description 1
• 239000007940 sugar coated tablet Substances 0.000 description 1
• 230000000699 topical effect Effects 0.000 description 1
• 231100000331 toxic Toxicity 0.000 description 1
• 230000002588 toxic effect Effects 0.000 description 1
• 238000002525 ultrasonication Methods 0.000 description 1
• 229940116269 uric acid Drugs 0.000 description 1
• 239000011782 vitamin Substances 0.000 description 1
• 229930003231 vitamin Natural products 0.000 description 1
• 235000013343 vitamin Nutrition 0.000 description 1
• 229940088594 vitamin Drugs 0.000 description 1