JPS6223822B2 - - Google Patents

Info

Publication number
JPS6223822B2
JPS6223822B2 JP55068040A JP6804080A JPS6223822B2 JP S6223822 B2 JPS6223822 B2 JP S6223822B2 JP 55068040 A JP55068040 A JP 55068040A JP 6804080 A JP6804080 A JP 6804080A JP S6223822 B2 JPS6223822 B2 JP S6223822B2
Authority
JP
Japan
Prior art keywords
asn
peptide
lys
arg
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55068040A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56163456A (en
Inventor
Noboru Yanaihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP6804080A priority Critical patent/JPS56163456A/ja
Priority to SE8103198A priority patent/SE454301B/sv
Priority to DK222081A priority patent/DK159163C/da
Priority to BE0/204863A priority patent/BE888906A/fr
Priority to DE3120312A priority patent/DE3120312C2/de
Priority to GB8115648A priority patent/GB2079289B/en
Priority to US06/265,926 priority patent/US4407965A/en
Priority to FR8110140A priority patent/FR2482861A1/fr
Publication of JPS56163456A publication Critical patent/JPS56163456A/ja
Publication of JPS6223822B2 publication Critical patent/JPS6223822B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/822—Identified hapten
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP6804080A 1980-05-21 1980-05-21 Preparation of antigen Granted JPS56163456A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP6804080A JPS56163456A (en) 1980-05-21 1980-05-21 Preparation of antigen
SE8103198A SE454301B (sv) 1980-05-21 1981-05-20 Forfarande for framstellning av tarmglukagonantigen och motsvarande antikropp
DK222081A DK159163C (da) 1980-05-21 1981-05-20 Fremgangsmaade til fremstilling af et tarm-glucagon-antistof
BE0/204863A BE888906A (fr) 1980-05-21 1981-05-21 Procede de preparation d'un antigene et d'un anticorps du glucagon intestinal
DE3120312A DE3120312C2 (de) 1980-05-21 1981-05-21 Verfahren zur Herstellung von Darm-Glucagon-Antigenen und deren Verwendung
GB8115648A GB2079289B (en) 1980-05-21 1981-05-21 Process for preparing antibody
US06/265,926 US4407965A (en) 1980-05-21 1981-05-21 Process for preparing antibody
FR8110140A FR2482861A1 (fr) 1980-05-21 1981-05-21 Procede de preparation d'un antigene et d'un anticorps du glucagon intestinal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6804080A JPS56163456A (en) 1980-05-21 1980-05-21 Preparation of antigen

Publications (2)

Publication Number Publication Date
JPS56163456A JPS56163456A (en) 1981-12-16
JPS6223822B2 true JPS6223822B2 (enFirst) 1987-05-25

Family

ID=13362282

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6804080A Granted JPS56163456A (en) 1980-05-21 1980-05-21 Preparation of antigen

Country Status (8)

Country Link
US (1) US4407965A (enFirst)
JP (1) JPS56163456A (enFirst)
BE (1) BE888906A (enFirst)
DE (1) DE3120312C2 (enFirst)
DK (1) DK159163C (enFirst)
FR (1) FR2482861A1 (enFirst)
GB (1) GB2079289B (enFirst)
SE (1) SE454301B (enFirst)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572800A (en) * 1982-09-30 1986-02-25 Otsuka Pharmaceutical Co., Ltd. Human leukemia virus-related peptides, a process for production thereof, antibodies of the peptides and a process for production of the antibodies
CA1256795A (en) * 1983-12-28 1989-07-04 Dennis A. Carson Anti-idiotype antibodies induced by synthetic polypeptides
US4545985A (en) * 1984-01-26 1985-10-08 The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services Pseudomonas exotoxin conjugate immunotoxins
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
US4654419A (en) * 1984-08-08 1987-03-31 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen
US5116725A (en) * 1984-08-08 1992-05-26 Scripps Clinic And Research Foundation Assay for Epstein-Barr virus infection with solid phase bound synthetic polypeptides
JPS62500452A (ja) * 1984-09-19 1987-02-26 ザ　リ−ジエンツ　オブ　ザ　ユニバ−シテイ　オブ　カリフオルニア ヒト細胞形質転換に関連するレトロウイルスポリペプチド
US4732863A (en) * 1984-12-31 1988-03-22 University Of New Mexico PEG-modified antibody with reduced affinity for cell surface Fc receptors
JPH0792458B2 (ja) * 1986-03-14 1995-10-09 郁男 山科 糖鎖特異抗体アツセイプレ−ト及びその製造方法
US5202270A (en) * 1986-05-15 1993-04-13 Abbott Laboratories Cocaine and cocaine metabolites assay tracers, immunogens and antibodies
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
MX2017003535A (es) 2014-09-16 2017-10-27 Regeneron Pharma Anticuerpos anti-glucagon y sus usos.
KR102708864B1 (ko) 2016-08-30 2024-09-25 리제너론 파마슈티칼스 인코포레이티드 글루카곤 수용체 신호전달을 간섭함에 의한 중증 인슐린 저항성의 치료 방법
US20190248888A1 (en) 2016-10-20 2019-08-15 Regeneron Pharmaceuticals, Inc. Methods of lowering blood glucose levels
JP7781519B2 (ja) 2017-08-22 2025-12-08 リジェネロン・ファーマシューティカルズ・インコーポレイテッド グルカゴン受容体シグナル伝達に干渉することによって尿素サイクル異常症を治療する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5836308B2 (ja) * 1977-02-10 1983-08-08 大塚製薬株式会社 抗体の製造方法
US4206199A (en) * 1977-07-22 1980-06-03 Takeda Chemical Industries, Ltd. Novel glucagon fragment and its derivatives

Also Published As

Publication number Publication date
DE3120312A1 (de) 1982-03-04
DK159163B (da) 1990-09-10
DK222081A (da) 1981-11-22
BE888906A (fr) 1981-11-23
DE3120312C2 (de) 1985-08-29
DK159163C (da) 1991-02-11
US4407965A (en) 1983-10-04
FR2482861B1 (enFirst) 1983-09-09
FR2482861A1 (fr) 1981-11-27
GB2079289A (en) 1982-01-20
JPS56163456A (en) 1981-12-16
GB2079289B (en) 1983-10-26
SE8103198L (sv) 1981-11-22
SE454301B (sv) 1988-04-18

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