JPS62155285A - 生理活性物質ｋ−２５２の誘導体 - Google Patents

生理活性物質ｋ−２５２の誘導体

Info

Publication number
JPS62155285A
JPS62155285A JP29517385A JP29517385A JPS62155285A JP S62155285 A JPS62155285 A JP S62155285A JP 29517385 A JP29517385 A JP 29517385A JP 29517385 A JP29517385 A JP 29517385A JP S62155285 A JPS62155285 A JP S62155285A
Authority
JP
Japan
Prior art keywords
compound
formula
solution
room temperature
thf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP29517385A
Other languages
English (en)
Japanese (ja)
Other versions
JPH051795B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Tadashi Hirata
平田　正
Mitsuru Takahashi
充 高橋
Tsutomu Muragata
力 村形
Hiroshi Kase
廣 加瀬
Koji Yamada
耕二 山田
Kazuyuki Iwahashi
和幸 岩橋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP29517385A priority Critical patent/JPS62155285A/ja
Publication of JPS62155285A publication Critical patent/JPS62155285A/ja
Publication of JPH051795B2 publication Critical patent/JPH051795B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP29517385A 1985-12-27 1985-12-27 生理活性物質ｋ−２５２の誘導体 Granted JPS62155285A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP29517385A JPS62155285A (ja) 1985-12-27 1985-12-27 生理活性物質ｋ−２５２の誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29517385A JPS62155285A (ja) 1985-12-27 1985-12-27 生理活性物質ｋ−２５２の誘導体

Publications (2)

Publication Number Publication Date
JPS62155285A true JPS62155285A (ja) 1987-07-10
JPH051795B2 JPH051795B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-11

Family

ID=17817174

Family Applications (1)

Application Number Title Priority Date Filing Date
JP29517385A Granted JPS62155285A (ja) 1985-12-27 1985-12-27 生理活性物質ｋ−２５２の誘導体

Country Status (1)

Country Link
JP (1) JPS62155285A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61268687A (ja) * 1985-05-24 1986-11-28 Meiji Seika Kaisha Ltd Ｓｆ−２３７０物質誘導体およびその製造法
US4877776A (en) * 1987-12-24 1989-10-31 Kyowa Hakko Kogyo Co., Ltd. K-252 compounds
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
WO1994016706A1 (en) 1993-01-28 1994-08-04 Neorx Corporation Therapeutic inhibitors of vascular smooth muscle cells
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
EP0699204A4 (en) * 1993-05-28 1996-01-10 Cephalon Inc APPLICATION OF INDOLOCARBAZOLE DERIVATIVES FOR THE TREATMENT OF PROSTATE DISEASES
WO1996013506A1 (en) * 1994-10-26 1996-05-09 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US5599808A (en) * 1994-02-18 1997-02-04 Cephalon, Inc. Aqueous indolocarbazole solutions
US5621101A (en) * 1992-07-24 1997-04-15 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US6184217B1 (en) 1996-06-25 2001-02-06 Cephalon, Inc. Use of K-252a derivative
US6200968B1 (en) 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US6306849B1 (en) 1996-06-03 2001-10-23 Cephalon, Inc. Selected derivatives of K-252a
US6875865B1 (en) 1996-06-03 2005-04-05 Cephalon, Inc. Selected derivatives of K-252a
WO2007070444A1 (en) * 2005-12-09 2007-06-21 Abbott Laboratories Lestaurtinib crystalline form 1, crystalline lestaurimib anhydrate and amorphous lestaurimib
EP2098230A1 (en) 1997-03-31 2009-09-09 Boston Scientific Scimed Limited Use of cytoskeletal inhibitors in crystalline form for the inhibition or prevention of restenosis
US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
EP2292225A1 (en) 1997-03-31 2011-03-09 Boston Scientific Scimed Limited Dosage form comprising taxol in crystalline form

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61268687A (ja) * 1985-05-24 1986-11-28 Meiji Seika Kaisha Ltd Ｓｆ−２３７０物質誘導体およびその製造法
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
US4877776A (en) * 1987-12-24 1989-10-31 Kyowa Hakko Kogyo Co., Ltd. K-252 compounds
AU675236B2 (en) * 1992-07-24 1997-01-30 Cephalon, Inc. Bis-staurosporine and K-252a derivatives
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
US5621101A (en) * 1992-07-24 1997-04-15 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US5741808A (en) * 1992-07-24 1998-04-21 Cephalon, Inc. Protein kinase inhibitors for treatmen of neurological disorders
US5756494A (en) * 1992-07-24 1998-05-26 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
WO1994016706A1 (en) 1993-01-28 1994-08-04 Neorx Corporation Therapeutic inhibitors of vascular smooth muscle cells
EP2298310A2 (en) 1993-01-28 2011-03-23 Boston Scientific Limited Therapeutic inhibitors of vascular smooth muscle cells
EP2324829A1 (en) 1993-01-28 2011-05-25 Boston Scientific Limited Therapeutic inhibitors of vascular smooth muscle cells
EP0699204A4 (en) * 1993-05-28 1996-01-10 Cephalon Inc APPLICATION OF INDOLOCARBAZOLE DERIVATIVES FOR THE TREATMENT OF PROSTATE DISEASES
US5516771A (en) * 1993-05-28 1996-05-14 Cephalon, Inc. Use of indolocarbazole derivatives to treat a pathological condition of the prostate
US5654427A (en) * 1993-05-28 1997-08-05 Kyowa Hakko Kogyo Co., Ltd. Indolocarbazole derivatives to treat a pathological condition of the prostate
EP0839814A3 (en) * 1993-05-28 1998-09-16 Cephalon, Inc. Indolocarbazole derivatives and their use for the treatment of prostate gland disorders
US5599808A (en) * 1994-02-18 1997-02-04 Cephalon, Inc. Aqueous indolocarbazole solutions
WO1996013506A1 (en) * 1994-10-26 1996-05-09 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
EP1125938A1 (en) * 1994-10-26 2001-08-22 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US6306849B1 (en) 1996-06-03 2001-10-23 Cephalon, Inc. Selected derivatives of K-252a
US6875865B1 (en) 1996-06-03 2005-04-05 Cephalon, Inc. Selected derivatives of K-252a
US6184217B1 (en) 1996-06-25 2001-02-06 Cephalon, Inc. Use of K-252a derivative
EP2098230A1 (en) 1997-03-31 2009-09-09 Boston Scientific Scimed Limited Use of cytoskeletal inhibitors in crystalline form for the inhibition or prevention of restenosis
EP2292225A1 (en) 1997-03-31 2011-03-09 Boston Scientific Scimed Limited Dosage form comprising taxol in crystalline form
US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US6200968B1 (en) 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
WO2007070444A1 (en) * 2005-12-09 2007-06-21 Abbott Laboratories Lestaurtinib crystalline form 1, crystalline lestaurimib anhydrate and amorphous lestaurimib

Also Published As

Publication number Publication date
JPH051795B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-11

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