JPS62138198A - 自己顕色性基質を含む乾式液体分析要素 - Google Patents
自己顕色性基質を含む乾式液体分析要素Info
- Publication number
- JPS62138198A JPS62138198A JP60277414A JP27741485A JPS62138198A JP S62138198 A JPS62138198 A JP S62138198A JP 60277414 A JP60277414 A JP 60277414A JP 27741485 A JP27741485 A JP 27741485A JP S62138198 A JPS62138198 A JP S62138198A
- Authority
- JP
- Japan
- Prior art keywords
- layer
- water
- liquid
- developing
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 41
- 239000000758 substrate Substances 0.000 title claims abstract description 41
- 238000004458 analytical method Methods 0.000 title claims description 24
- BTJIUGUIPKRLHP-UHFFFAOYSA-N 4-nitrophenol Chemical compound OC1=CC=C([N+]([O-])=O)C=C1 BTJIUGUIPKRLHP-UHFFFAOYSA-N 0.000 claims abstract description 28
- 102000004190 Enzymes Human genes 0.000 claims abstract description 21
- 108090000790 Enzymes Proteins 0.000 claims abstract description 21
- 229920006317 cationic polymer Polymers 0.000 claims abstract description 21
- 229920000642 polymer Polymers 0.000 claims abstract description 19
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims abstract description 4
- 238000003892 spreading Methods 0.000 claims description 23
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- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
- 229920000936 Agarose Polymers 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 2
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- 125000003118 aryl group Chemical group 0.000 description 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
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- LHCADHHKYDKVHY-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene prop-1-enylbenzene Chemical compound CC=CC1=CC=CC=C1.C=CC1=CC=CC=C1C=C LHCADHHKYDKVHY-UHFFFAOYSA-N 0.000 description 1
- WDRZVZVXHZNSFG-UHFFFAOYSA-N 1-ethenylpyridin-1-ium Chemical compound C=C[N+]1=CC=CC=C1 WDRZVZVXHZNSFG-UHFFFAOYSA-N 0.000 description 1
- IQUPABOKLQSFBK-UHFFFAOYSA-N 2-nitrophenol Chemical compound OC1=CC=CC=C1[N+]([O-])=O IQUPABOKLQSFBK-UHFFFAOYSA-N 0.000 description 1
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 229920000945 Amylopectin Polymers 0.000 description 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 1
- PDYDNBADCBSQBN-UHFFFAOYSA-N CC=CC1=CC=CC=C1.CN1CCOCC1.C=CC1=CC=CC=C1.C=CC1=C(C=C)C=CC=C1 Chemical compound CC=CC1=CC=CC=C1.CN1CCOCC1.C=CC1=CC=CC=C1.C=CC1=C(C=C)C=CC=C1 PDYDNBADCBSQBN-UHFFFAOYSA-N 0.000 description 1
- 229920008347 Cellulose acetate propionate Polymers 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- 229920002284 Cellulose triacetate Polymers 0.000 description 1
- 102000002464 Galactosidases Human genes 0.000 description 1
- 108010093031 Galactosidases Proteins 0.000 description 1
- 239000006173 Good's buffer Substances 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 235000010724 Wisteria floribunda Nutrition 0.000 description 1
- NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
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- 125000003172 aldehyde group Chemical group 0.000 description 1
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- 210000004369 blood Anatomy 0.000 description 1
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- 150000001642 boronic acid derivatives Chemical class 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
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- 239000006229 carbon black Substances 0.000 description 1
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- 229920002301 cellulose acetate Polymers 0.000 description 1
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- 125000004965 chloroalkyl group Chemical group 0.000 description 1
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- 238000004737 colorimetric analysis Methods 0.000 description 1
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- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 208000028659 discharge Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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- 229920000172 poly(styrenesulfonic acid) Polymers 0.000 description 1
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- 229920002223 polystyrene Polymers 0.000 description 1
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- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000006207 propylation Effects 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 description 1
- 239000000985 reactive dye Substances 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 description 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- 229960004555 rutoside Drugs 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
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- 125000001302 tertiary amino group Chemical group 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
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- 230000000007 visual effect Effects 0.000 description 1
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- 229920003176 water-insoluble polymer Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/40—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
- G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/10—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases p-Nitrophenol derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60277414A JPS62138198A (ja) | 1985-12-10 | 1985-12-10 | 自己顕色性基質を含む乾式液体分析要素 |
| US06/939,856 US5077011A (en) | 1985-12-10 | 1986-12-09 | Dry analytical element containing self-developing substrate for use in analysis of liquid |
| GB8629577A GB2183832B (en) | 1985-12-10 | 1986-12-10 | Dry analytical element containing self-developing substrate for use in analysis of liquid |
| DE3642189A DE3642189C2 (de) | 1985-12-10 | 1986-12-10 | Trockenes analytisches Element zur Verwendung bei der Analyse einer Flüssigkeit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60277414A JPS62138198A (ja) | 1985-12-10 | 1985-12-10 | 自己顕色性基質を含む乾式液体分析要素 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62138198A true JPS62138198A (ja) | 1987-06-20 |
| JPH0550274B2 JPH0550274B2 (enrdf_load_stackoverflow) | 1993-07-28 |
Family
ID=17583215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60277414A Granted JPS62138198A (ja) | 1985-12-10 | 1985-12-10 | 自己顕色性基質を含む乾式液体分析要素 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5077011A (enrdf_load_stackoverflow) |
| JP (1) | JPS62138198A (enrdf_load_stackoverflow) |
| DE (1) | DE3642189C2 (enrdf_load_stackoverflow) |
| GB (1) | GB2183832B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008194036A (ja) * | 2007-01-17 | 2008-08-28 | Fujifilm Corp | 動物α−アミラーゼ測定方法 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334955C (en) * | 1988-11-21 | 1995-03-28 | Kenneth R. Makowka | Tamper-evident sealing system for envelope and method of making same |
| EP0535485B1 (en) * | 1991-10-03 | 1997-07-16 | Bayer Corporation | Device and method of separating and assaying whole blood |
| US5981206A (en) * | 1992-05-20 | 1999-11-09 | Johnson & Johnson Clinical Diagnostic Systems, Inc. | Dry analytical element and method for the detection of prostatic acid phosphatase |
| US5874229A (en) * | 1995-08-07 | 1999-02-23 | Kyoto Daiichi Kagaku Co., Ltd. | Method for avoiding influence of hemoglobin |
| GB9519393D0 (en) * | 1995-09-22 | 1995-11-22 | Univ Edinburgh | Novel compounds and assay method |
| US7183069B2 (en) | 2002-03-07 | 2007-02-27 | Toyama University | Reagent, method and apparatus for measuring amylase activity |
| US7186696B2 (en) * | 2002-03-07 | 2007-03-06 | Toyama University | Reagent and method for measuring amylase |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2280081A1 (fr) * | 1974-07-23 | 1976-02-20 | Kodak Pathe | Produit composite unitaire pour l'analyse chimique ou biologique |
| US4069017A (en) * | 1977-01-14 | 1978-01-17 | Eastman Kodak Company | Colorimetric assay for bilirubin |
| US4102747A (en) * | 1977-07-28 | 1978-07-25 | American Hospital Supply Corporation | Amylase determination |
| CA1122889A (en) * | 1977-08-08 | 1982-05-04 | Eastman Kodak Company | Reduction of detectable species migration in elements for the analysis of liquids |
| US4153668A (en) * | 1978-01-03 | 1979-05-08 | Eastman Kodak Company | Multi-zone analytical element and method using same |
| US4274832A (en) * | 1979-02-12 | 1981-06-23 | Eastman Kodak Company | Analytical element and method for analysis of multiple analytes |
| JPS5899752A (ja) * | 1981-11-04 | 1983-06-14 | Konishiroku Photo Ind Co Ltd | 多層分析素子 |
| JP2546981B2 (ja) * | 1982-09-07 | 1996-10-23 | コニカ株式会社 | 多層分析素子 |
| JPS6010171A (ja) * | 1983-06-30 | 1985-01-19 | Fuji Photo Film Co Ltd | 多層分析要素 |
-
1985
- 1985-12-10 JP JP60277414A patent/JPS62138198A/ja active Granted
-
1986
- 1986-12-09 US US06/939,856 patent/US5077011A/en not_active Expired - Lifetime
- 1986-12-10 GB GB8629577A patent/GB2183832B/en not_active Expired - Lifetime
- 1986-12-10 DE DE3642189A patent/DE3642189C2/de not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008194036A (ja) * | 2007-01-17 | 2008-08-28 | Fujifilm Corp | 動物α−アミラーゼ測定方法 |
| US8906641B2 (en) | 2007-01-17 | 2014-12-09 | Fujifilm Corporation | Method for measuring animal α-amylase |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2183832B (en) | 1990-05-02 |
| GB2183832A (en) | 1987-06-10 |
| GB8629577D0 (en) | 1987-01-21 |
| DE3642189C2 (de) | 1997-10-02 |
| JPH0550274B2 (enrdf_load_stackoverflow) | 1993-07-28 |
| DE3642189A1 (de) | 1987-06-11 |
| US5077011A (en) | 1991-12-31 |
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| LAPS | Cancellation because of no payment of annual fees |