JPS61210100A - 魚類の新規成長ホルモンポリペプチド - Google Patents
魚類の新規成長ホルモンポリペプチドInfo
- Publication number
- JPS61210100A JPS61210100A JP60050096A JP5009685A JPS61210100A JP S61210100 A JPS61210100 A JP S61210100A JP 60050096 A JP60050096 A JP 60050096A JP 5009685 A JP5009685 A JP 5009685A JP S61210100 A JPS61210100 A JP S61210100A
- Authority
- JP
- Japan
- Prior art keywords
- dna
- growth hormone
- fish
- polypeptide
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010051696 Growth Hormone Proteins 0.000 title claims abstract description 71
- 102000018997 Growth Hormone Human genes 0.000 title claims abstract description 69
- 241000251468 Actinopterygii Species 0.000 title claims abstract description 34
- 108020004414 DNA Proteins 0.000 claims abstract description 99
- 239000000122 growth hormone Substances 0.000 claims abstract description 44
- 241000588724 Escherichia coli Species 0.000 claims abstract description 32
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 23
- 108020004511 Recombinant DNA Proteins 0.000 claims abstract description 18
- 229920001184 polypeptide Polymers 0.000 claims abstract description 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 12
- 235000015097 nutrients Nutrition 0.000 claims abstract 2
- 239000013612 plasmid Substances 0.000 claims description 48
- 235000019688 fish Nutrition 0.000 claims description 33
- 244000005700 microbiome Species 0.000 claims description 16
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 238000012258 culturing Methods 0.000 claims description 4
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- 239000013598 vector Substances 0.000 abstract description 27
- 239000002299 complementary DNA Substances 0.000 abstract description 17
- 241000277329 Oncorhynchus keta Species 0.000 abstract description 13
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract description 12
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- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
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- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 9
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- 102100033215 DNA nucleotidylexotransferase Human genes 0.000 description 6
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- 238000003776 cleavage reaction Methods 0.000 description 5
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- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 4
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 101000658545 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) Type I restriction enyme HindI endonuclease subunit Proteins 0.000 description 2
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- 101100083503 Caenorhabditis elegans acl-1 gene Proteins 0.000 description 1
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- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 102000004594 DNA Polymerase I Human genes 0.000 description 1
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- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
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- 101000580317 Homo sapiens RNA 3'-terminal phosphate cyclase-like protein Proteins 0.000 description 1
- 102000002265 Human Growth Hormone Human genes 0.000 description 1
- 239000000854 Human Growth Hormone Substances 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
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- NKLPQNGYXWVELD-UHFFFAOYSA-M coomassie brilliant blue Chemical compound [Na+].C1=CC(OCC)=CC=C1NC1=CC=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C=CC(=CC=2)N(CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=C1 NKLPQNGYXWVELD-UHFFFAOYSA-M 0.000 description 1
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- FFYPMLJYZAEMQB-UHFFFAOYSA-N diethyl pyrocarbonate Chemical compound CCOC(=O)OC(=O)OCC FFYPMLJYZAEMQB-UHFFFAOYSA-N 0.000 description 1
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- 239000000594 mannitol Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Feed For Specific Animals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60050096A JPS61210100A (ja) | 1985-03-13 | 1985-03-13 | 魚類の新規成長ホルモンポリペプチド |
| CA000485108A CA1272144A (en) | 1984-06-29 | 1985-06-25 | Fish growth hormone polypeptide |
| NO852568A NO174717C (no) | 1984-06-29 | 1985-06-26 | Fremgangsmåte for fremstilling av et fiskeveksthormon-polypeptid fra Oncorhynchus keta samt ekspresjonsvektorer til bruk ved fremgangsmåten |
| AU44195/85A AU575961B2 (en) | 1984-06-29 | 1985-06-26 | Salmon fish growth hormone by genetic engeneering |
| EP85107987A EP0166444B1 (en) | 1984-06-29 | 1985-06-27 | Fish growth hormone polypeptide |
| SU853913602A RU1825376C (ru) | 1984-06-29 | 1985-06-28 | Способ получени ДНК, кодирующей гормон роста лосос , способ конст-ни промежуточной рекомбинантной плазмидной ДНК, содержащей ДНК-фрагмент, кодирующий гормон роста лосос , дл получени плазмид pS GH1, pS GH3, pS GH9, pS GH10, pS GH14 и pS GH17, способ получени реком-ной плазмидной ДНК pS GH1B2, кодирующей гормон роста лосос , способ получени реком-ной плазмидной ДНК pSGH II С2, кодирующей гормон роста лосос , способ получени реком-ного гормона роста лосос |
| CN 85104988 CN85104988A (zh) | 1984-10-12 | 1985-07-01 | 鱼生长激素多肽 |
| US06/750,587 US4689402A (en) | 1984-06-29 | 1985-07-01 | Fish growth hormone polypeptide |
| US07/017,630 US4849359A (en) | 1984-06-29 | 1987-04-14 | Fish growth hormone polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60050096A JPS61210100A (ja) | 1985-03-13 | 1985-03-13 | 魚類の新規成長ホルモンポリペプチド |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4066978A Division JPH05268969A (ja) | 1992-03-25 | 1992-03-25 | 魚類の新規成長ホルモンポリペプチド |
| JP4204982A Division JPH0695938B2 (ja) | 1992-07-31 | 1992-07-31 | 魚類の新規成長ホルモンポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61210100A true JPS61210100A (ja) | 1986-09-18 |
| JPH051800B2 JPH051800B2 (es) | 1993-01-11 |
Family
ID=12849529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60050096A Granted JPS61210100A (ja) | 1984-06-29 | 1985-03-13 | 魚類の新規成長ホルモンポリペプチド |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61210100A (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02501259A (ja) * | 1986-12-31 | 1990-05-10 | 株式会社ラッキー | 合成遺伝子を使用したサケ成長ホルモンの製造方法 |
-
1985
- 1985-03-13 JP JP60050096A patent/JPS61210100A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02501259A (ja) * | 1986-12-31 | 1990-05-10 | 株式会社ラッキー | 合成遺伝子を使用したサケ成長ホルモンの製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH051800B2 (es) | 1993-01-11 |
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