JPS61207336A - Analgesic and anti-inflammatory agent - Google Patents

Abstract

PURPOSE:To provide an analgesic and anti-inflammatory agent obtained by extracting or dissolving pine leaves and various pine rosins with vaseline or oil and fat and useful for the mitigation, removal and cure of pain by external application. CONSTITUTION:The leaves of pine and the rosin of various parts of pine (e.g. Pinus thunbergii, Pinus densiflora, Pinus palustris, etc.) is plucked, cut to small pieces, and dried in the shade. The treated pine is immersed in molten hot vaselin or oil and fat, and heated at 150-160 deg.C for about 25-30min to effect the extraction or dissolution of the pine components. The product is filtered under pressure to obtain the objective ointment having yellowish brown color. The ointment is applied to the painful part once or twice a day in the form of an endermic liniment or plaster. It has temporary paralyzing effect to the nervous system and strong action to radically promote the normalization of the function of the tissue. It is useful for the mitigation of various pains such as lumbago, arthritis, shoulder pain, muscular pain, stomach ache, cough, sprain, etc.

Description

[Detailed Description of the Invention] t1) This drug was confirmed to have excellent efficacy in removing various types of pain and extinguishing inflammation inside the skin and muscles during the testing of a hemorrhoid treatment agent. In terms of removal and relief, it is a transdermal agent that acts extremely quickly and can be used for a wide variety of purposes in various parts of the human body as a highly safe therapeutic agent.

In addition, this drug does not have a temporary suppressing effect; it acts on the roots and surrounding tissue nerve stalks, promoting normal blood flow, eliminating pain, and at the same time leading to relief through healing and action. It is.

In the case of disorders such as direct and indirect pain and numbness in the skin and lower muscles, local complaints can be alleviated and removed by application or patching, and it is also of high utility value in the case of stiffness, etc. In addition, when used on the skin, it has a transdermal effect on pain in the body, as well as pain in internal organs, and can eliminate and alleviate pain.

(2) The root of various symptoms that occur in the human body, such as pain, sores, stiffness, etc., is the transmission of information that begins with irregular blood flow and is transmitted to the nervous system within cells. Removing inflammation is basically the human body's ff3 healing ability, but unfortunately due to various adverse conditions, natural healing requires a long period of pain, and furthermore, due to limitations such as physical strength, it can become worse. 4I is coming! ! It is accompanied by symptoms.

The characteristic action of this principle is not only to relieve pain by temporarily paralyzing the nerve pedicle, but also to fundamentally promote the normalization of tissue function, to calm pain, and to eliminate inflammation.

Regarding Examples, etc., experiments are used as described below. however,
It is used by coating.

1. In case of pain such as muscle pain, bruises, sprains, etc.

If you apply it to the painful area, the pain will be instantly relieved, and subsequent use will also relieve the inflammation.

2. For toothache and gingival inflammation pain, apply it to the gingiva and sore tooth and the pain will be instantly relieved.

After that, the inflammation of the gums can be removed by using it several times.
3. In the case of a sore throat due to cough or tracheitis, etc. 2. Applying it to the local skin surface will quickly relieve the pain and soothe the throat.

4. In the case of neuralgia, v4# inflammation, and lower back pain, the pain will be alleviated by applying it, and you will gradually get better with continuous use.

5. In the case of internal P organ pain such as abdominal pain, if you apply it to the epidermis near the pain, it will act on the pathway (neural gyrus MI) from the sewing point after a few minutes, causing borborygmus and gas generation, causing pain. is gradually removed.

6. Even in the case of numbness, stiffness, etc., if you apply it to the complaining area, the symptoms will be relieved. 7. If you use it in case of pain, such as a cut, the itching will immediately stop.

As for the manufacturing method, it is manufactured using a coating agent and other manufacturing methods using a simple patch scraper.

The basic manufacturing method is 1 g of green pine leaves cut and dried, and 2 g of Matsuko 629 same resin that can be dried and cut to increase &&.
Extract the components sufficiently from Vaseline 409 in a heated solution and filter.

Cooling: Prepare by mixing other substances as necessary.

However, if it is manufactured as a single oral preparation, it is extracted with other fats and oils.

The basic usage method is to apply (patch) once or twice a day (8)
The efficacy is as described in the Examples section.

It can be used for a wide range of pain areas, has high value as a fast-acting painkiller, and is expected to have unparalleled efficacy.

Progress of use 1 For example, in case of severe pain from a bruise.

In the case of toothache in the mouth or mucosal cancer, the pain will disappear immediately after use, and the effect is not only temporary, fI31h
It has a strong effect that leads to safety, so it is a fundamental principle that has unlimited possibilities in terms of its effectiveness and safety.

Procedural amendment (spontaneous) 1, Indication of case Patent application No. 049635 of 1985.

2. Title of the invention: Analgesic and anti-inflammatory agent 3. Relationship with the amended person's case: Who is the patent applicant?
4 Address (residence) 2813 Sakuzu, Kurashiki City, Okayama Prefecture Contents of amendment in section 9 Explanation Full text description as attached Document 1 Name of the invention Analgesic anti-inflammatory agent 2 Scope of claims (1) Pine (Pine) Extract or dissolve the leaves and interpartial resins of the pine tree (genus Pinus) with vaseline or oils and apply it externally to remove pain and extinguish inflammation in various parts of the human body using a method similar to applying. A method of manufacturing for a specific purpose. (However, hemorrhoids are excluded) 3. Detailed description of the invention (1) Powder medicines can safely and easily relieve and eliminate pain in various parts of the human body, which is a major problem for the human body, by external application etc. It is an analgesic and anti-inflammatory agent with a wide range of uses, leading to healing, and has unique properties.

The discovery of the water solution was confirmed during the development of a treatment for athlete's foot to have a specific effect on the pain of hemorrhoids. The composition of the powder is made by heating and melting Vaseline (white/yellow), adding appropriately processed parts of pine (shredded, dried in the shade) to the liquid, and dissolving and extracting it to carbonize the main component of Vaseline. Essential oil components contained in pine and dextro pimaric acid (0
20H2O02) abietic acid (02G■3o02) and sodium salt pond carbohydrates with high mr (ctso'
~160') The components are dissolved and combined into a yellowish-brown ointment.The exact relationship between the fluorescent substances in Refuselin and the pine components is unclear, but Similar extractions are made in fats and oils, but they cannot be expected to have the same effect as a powder (experimentally).It is believed that the substances in petrolatum act synergistically with the ingredients in pine to produce ingredients that are effective for analgesia. (The above-mentioned Vaseline is liquefied at high temperature and the components of Nakamatsu are saponified.) It becomes Urum salt, and hydrocarbons and fluorescent substances are also involved, and it becomes a substance that acts electrically on the nervous system, causing various types of pain inside the muscles. It has excellent removal and mitigation effects.

(2) The effect of the powder on the human body can be sufficiently exerted for a short period of time by applying the powder to the epidermis of the sore, etc. In the case of superficial pain, bruises, etc., it takes about 1 to 3 minutes. In addition, in the case of deep and difficult arthritis (shin region), it acts quickly in about 10 minutes, so it is considered difficult to penetrate directly to the painful area. It electrically responds to the nervous system (blood flow system and acupuncture point system) and is transmitted not only to the superficial part of the cell but also to the deep part of the cell, calming pain from the direction of blood flow (for 10 minutes or more when applied to the surface skin of the abdomen in an experiment)
It acts on the deep parts of the internal stomach, intestines, etc. in about 13 minutes, and is not an anesthetic, so it has a property that leads to a healing effect rather than a temporary analgesic effect.

Regarding the manufacturing method, a coating agent and a simple patch were made, and the types of pine trees used for the trial were Kuromatsu and Akamatsu Guiosho. In this volume, we will describe topical preparations and omit the topic of patches.

First, in preparation for the ingredients, harvest from the mature leaves of fresh green pine 61~
Cut into pieces about 10m+ and dry in the shade (7 to 10 days). Twigs are also shredded into pieces of 5wIR to 7Tm and dried in the shade (5 to 7 days)
do. The dried resin is collected directly from home and used as is.

Heat 50g of Vaseline (white/yellow) (050° to 60°)
Melt the dried shredded pine leaves, add 9 y, 7 g of the same twigs, and 2 g of the same resin. It takes about 25 to 30 minutes to make a yellow-brown ointment. Since a large amount of foam overflows during the production of the liquid medicine, a large container is used and the hot liquid is quickly squeezed and filtered at the same time.

(3) Regarding Examples, etc., experiments will be used as described below.

However, it should be used externally (once to twice a day).Breakdown of use in the analgesic and anti-inflammatory test: low back pain, arthritis, shoulder pain, bruises, sitting pain, muscle pain, sore throat, abdominal pain, numbness, stiffness, cough, Terminal cancer pain (abdominal) 1. If you have pain from muscle pain, shoulder pain, bruises, sitting upright, etc., apply it to the painful area and the pain will be immediately relieved, and subsequent use will also remove inflammation.

2. If you have a cough or a sore throat due to tracheitis, applying it locally to the skin will calm the cough and soothe the sore throat.

3. In the case of curable arthritis or lower back pain, applying it will relieve the pain, and continuous use will gradually bring relief.

4. In case of pain due to terminal cancer, the pain will be relieved and relieved after 10 to 15 minutes of use.

5. In case of pain in internal organs such as abdominal pain, if applied to the epidermis near the pain, the pain will be alleviated and gradually removed after 10 minutes.

6. In the case of numbness, stiffness, etc., if you apply it to the affected area, the former will have an immediate effect, while the latter will have a delayed effect.

Symptoms begin to improve.

(4) As for the efficacy, as described in the Examples section (it can be used for a wide range of pain areas), it has high value as a fast-acting painkiller, and has unparalleled efficacy. I can expect it.

The characteristic action of the powder is that it not only temporarily paralyzes the nervous system and eliminates pain, but also has a strong action that fundamentally promotes normalization of tissue function, and has a strong action that leads to analgesia and healing. It is an epoch-making, special analgesic and anti-inflammatory drug that has unlimited potential in terms of safety and utility.

Claims (1)

[Claims] (1) Extract the pine needles, various parts of the pine tree, and the same resin with vaseline (oils and fats), mix in other substances as necessary, and use it to remove pain and extinguish inflammation in the skin, muscles, and other parts of the body. (However, excluding hemorrhoids) Methods for producing analgesic and anti-inflammatory agents using coating or patching methods and other methods.