JPS6118781A - ピロロ〔１，２‐ｂ〕〔１，２，５〕トリアゼピンおよびそれらの製法 - Google Patents

ピロロ〔１，２‐ｂ〕〔１，２，５〕トリアゼピンおよびそれらの製法

Info

Publication number
JPS6118781A
JPS6118781A JP60142673A JP14267385A JPS6118781A JP S6118781 A JPS6118781 A JP S6118781A JP 60142673 A JP60142673 A JP 60142673A JP 14267385 A JP14267385 A JP 14267385A JP S6118781 A JPS6118781 A JP S6118781A
Authority
JP
Japan
Prior art keywords
formula
compound
hydrogen
formulas
mathematical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60142673A
Other languages
English (en)
Japanese (ja)
Inventor
リチヤード・シー・エフランド
ジヨゼフ・テイー・クライン
アール・リチヤード・エル・ハマー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of JPS6118781A publication Critical patent/JPS6118781A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/50—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
JP60142673A 1984-07-02 1985-07-01 ピロロ〔１，２‐ｂ〕〔１，２，５〕トリアゼピンおよびそれらの製法 Pending JPS6118781A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US627329 1984-07-02
US06/627,329 US4517195A (en) 1984-07-02 1984-07-02 Pyrrolo[1,2-b][1,2,5]triazepines and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
JPS6118781A true JPS6118781A (ja) 1986-01-27

Family

ID=24514226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60142673A Pending JPS6118781A (ja) 1984-07-02 1985-07-01 ピロロ〔１，２‐ｂ〕〔１，２，５〕トリアゼピンおよびそれらの製法

Country Status (13)

Country Link
US (1) US4517195A (enExample)
EP (1) EP0167922B1 (enExample)
JP (1) JPS6118781A (enExample)
KR (1) KR860001113A (enExample)
AT (1) ATE51401T1 (enExample)
AU (2) AU593771B2 (enExample)
CA (1) CA1251790A (enExample)
DE (1) DE3576822D1 (enExample)
DK (1) DK298085A (enExample)
ES (5) ES8702913A1 (enExample)
GR (1) GR851599B (enExample)
PT (1) PT80746B (enExample)
ZA (1) ZA854946B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06184097A (ja) * 1992-07-30 1994-07-05 Hoechst Roussel Pharmaceut Inc １−アミノアセトアミドピロールおよび１−アミノアセトアミド−２−（置換）ピロールならびに関連化合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800203A (en) * 1987-09-24 1989-01-24 Hoechst-Roussel Pharmaceuticals, Inc. Pyrrolo(1,2-b)cinnolines
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121081A (en) * 1961-08-18 1964-02-11 Du Pont 6-amino-7, 8-dicyanopyrrolo [b]-as-triazines and 7-amino-8, 9-dicyanopyrrolo [b]-[1.2.4]triazepines and their preparation
US3116203A (en) * 1962-03-14 1963-12-31 Hoffmann La Roche Oleaginous systems
GB1433103A (en) * 1974-03-20 1976-04-22 Lepetit Spa Pharmacologically active pyrrolodiazepines
US4201712A (en) * 1975-07-16 1980-05-06 Boehringer Ingelheim Gmbh Process for preparation of 6-aryl-4H-s-triazolo-[3,4-c]-thieno-[2,3-e]-1,4-diazepines
FI803908L (fi) * 1979-12-21 1981-06-22 Sandoz Ag Nya pyrrolobenszotriazepiner deras framstaellning och dessa innehaollande farmaceutiska foereningar
GR76455B (enExample) * 1981-06-04 1984-08-10 Lepetit Spa

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06184097A (ja) * 1992-07-30 1994-07-05 Hoechst Roussel Pharmaceut Inc １−アミノアセトアミドピロールおよび１−アミノアセトアミド−２−（置換）ピロールならびに関連化合物

Also Published As

Publication number Publication date
DK298085A (da) 1986-01-03
ES8703836A1 (es) 1987-03-01
CA1262904C (enExample) 1989-11-14
ES544746A0 (es) 1987-01-16
ATE51401T1 (de) 1990-04-15
ES8702913A1 (es) 1987-01-16
US4517195A (en) 1985-05-14
PT80746A (en) 1985-08-01
EP0167922A2 (en) 1986-01-15
ES8707536A1 (es) 1987-08-01
ES552024A0 (es) 1987-03-01
ES8703837A1 (es) 1987-03-01
ES8703422A1 (es) 1987-02-16
EP0167922B1 (en) 1990-03-28
ES557083A0 (es) 1987-08-01
AU4451485A (en) 1986-01-09
PT80746B (en) 1987-02-13
AU4722889A (en) 1990-05-17
AU593771B2 (en) 1990-02-22
ES552023A0 (es) 1987-03-01
KR860001113A (ko) 1986-02-22
ZA854946B (en) 1986-02-26
GR851599B (enExample) 1985-11-25
CA1251790A (en) 1989-03-28
DK298085D0 (da) 1985-07-01
ES552022A0 (es) 1987-02-16
EP0167922A3 (en) 1987-01-21
DE3576822D1 (de) 1990-05-03

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