JPS6094063A - ホスファチジルコリン富有流動化混合物及びその製法 - Google Patents
ホスファチジルコリン富有流動化混合物及びその製法Info
- Publication number
- JPS6094063A JPS6094063A JP59193813A JP19381384A JPS6094063A JP S6094063 A JPS6094063 A JP S6094063A JP 59193813 A JP59193813 A JP 59193813A JP 19381384 A JP19381384 A JP 19381384A JP S6094063 A JPS6094063 A JP S6094063A
- Authority
- JP
- Japan
- Prior art keywords
- mixture
- metal ions
- weight
- phosphatidylcholine
- enriched fraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 57
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 230000009969 flowable effect Effects 0.000 title description 5
- 125000001095 phosphatidyl group Chemical group 0.000 title description 2
- 235000008979 vitamin B4 Nutrition 0.000 title 1
- 239000011579 vitamin B4 Substances 0.000 title 1
- 229910021645 metal ion Inorganic materials 0.000 claims abstract description 33
- 239000002904 solvent Substances 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 18
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims abstract description 18
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims abstract description 12
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 claims abstract description 9
- 150000008104 phosphatidylethanolamines Chemical class 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000011575 calcium Substances 0.000 claims description 6
- 238000005194 fractionation Methods 0.000 claims description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 4
- 229910001424 calcium ion Inorganic materials 0.000 claims description 4
- 229910001425 magnesium ion Inorganic materials 0.000 claims description 4
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- -1 phosphatidyl ethane Chemical compound 0.000 claims description 2
- JLQUFIHWVLZVTJ-UHFFFAOYSA-N carbosulfan Chemical compound CCCCN(CCCC)SN(C)C(=O)OC1=CC=CC2=C1OC(C)(C)C2 JLQUFIHWVLZVTJ-UHFFFAOYSA-N 0.000 claims 1
- 150000002433 hydrophilic molecules Chemical class 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 230000001476 alcoholic effect Effects 0.000 abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 27
- 239000000047 product Substances 0.000 description 18
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 13
- 239000000787 lecithin Substances 0.000 description 13
- 229940067606 lecithin Drugs 0.000 description 13
- 235000010445 lecithin Nutrition 0.000 description 13
- 239000003921 oil Substances 0.000 description 12
- 235000019198 oils Nutrition 0.000 description 12
- 239000012071 phase Substances 0.000 description 12
- 238000003860 storage Methods 0.000 description 9
- 235000014113 dietary fatty acids Nutrition 0.000 description 7
- 239000000194 fatty acid Substances 0.000 description 7
- 229930195729 fatty acid Natural products 0.000 description 7
- 150000004665 fatty acids Chemical class 0.000 description 7
- 239000003549 soybean oil Substances 0.000 description 7
- 235000012424 soybean oil Nutrition 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 244000068988 Glycine max Species 0.000 description 5
- 235000010469 Glycine max Nutrition 0.000 description 5
- 238000001704 evaporation Methods 0.000 description 5
- 230000008020 evaporation Effects 0.000 description 5
- 150000003626 triacylglycerols Chemical class 0.000 description 5
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000007791 liquid phase Substances 0.000 description 4
- 239000011777 magnesium Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 235000013310 margarine Nutrition 0.000 description 3
- 239000003264 margarine Substances 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- 235000019484 Rapeseed oil Nutrition 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 235000019486 Sunflower oil Nutrition 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000008240 homogeneous mixture Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000002600 sunflower oil Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 description 1
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 description 1
- DBGSRZSKGVSXRK-UHFFFAOYSA-N 1-[2-[5-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]-1,3,4-oxadiazol-2-yl]acetyl]-3,6-dihydro-2H-pyridine-4-carboxylic acid Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C1=NN=C(O1)CC(=O)N1CCC(=CC1)C(=O)O DBGSRZSKGVSXRK-UHFFFAOYSA-N 0.000 description 1
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 108091005960 Citrine Proteins 0.000 description 1
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 description 1
- 244000020551 Helianthus annuus Species 0.000 description 1
- 235000003222 Helianthus annuus Nutrition 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 239000011035 citrine Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 239000012263 liquid product Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 150000003905 phosphatidylinositols Chemical class 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229940083466 soybean lecithin Drugs 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Saccharide Compounds (AREA)
- Materials For Medical Uses (AREA)
- Edible Oils And Fats (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Fats And Perfumes (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8324672 | 1983-09-14 | ||
| GB838324672A GB8324672D0 (en) | 1983-09-14 | 1983-09-14 | Phosphatide mixture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6094063A true JPS6094063A (ja) | 1985-05-27 |
| JPH0355090B2 JPH0355090B2 (enExample) | 1991-08-22 |
Family
ID=10548806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59193813A Granted JPS6094063A (ja) | 1983-09-14 | 1984-09-14 | ホスファチジルコリン富有流動化混合物及びその製法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0141442B1 (enExample) |
| JP (1) | JPS6094063A (enExample) |
| AT (1) | ATE32826T1 (enExample) |
| CA (1) | CA1222654A (enExample) |
| DE (1) | DE3469672D1 (enExample) |
| DK (1) | DK437884A (enExample) |
| GB (1) | GB8324672D0 (enExample) |
| ZA (1) | ZA847226B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018500301A (ja) * | 2014-12-02 | 2018-01-11 | アーチャー−ダニエルズ−ミッドランド カンパニー | レシチンの機能性を改善する方法及びその応用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8616041D0 (en) * | 1986-07-01 | 1986-08-06 | Unilever Plc | Phosphatide-containing compositions |
| GB8620897D0 (en) * | 1986-08-29 | 1986-10-08 | Unilever Plc | Emulsions with reduced fat content |
| JPH0683633B2 (ja) * | 1987-04-08 | 1994-10-26 | 花王株式会社 | 食品用離型油組成物 |
| IL84840A0 (en) * | 1987-12-16 | 1988-06-30 | Rapaport Erich | Dietary supplement |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5554861A (en) * | 1978-10-16 | 1980-04-22 | Sugiyama Sangyo Kagaku Kenkyusho | Method of treating lecithin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3357918A (en) * | 1964-05-27 | 1967-12-12 | Central Soya Co | Fluidized lecithin composition and method |
| FR2343481A1 (fr) * | 1976-03-11 | 1977-10-07 | Gerlich Norbert | Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees |
| GR74979B (enExample) * | 1980-10-02 | 1984-07-12 | Unilever Nv |
-
1983
- 1983-09-14 GB GB838324672A patent/GB8324672D0/en active Pending
-
1984
- 1984-09-05 EP EP84201275A patent/EP0141442B1/en not_active Expired
- 1984-09-05 AT AT84201275T patent/ATE32826T1/de not_active IP Right Cessation
- 1984-09-05 DE DE8484201275T patent/DE3469672D1/de not_active Expired
- 1984-09-12 CA CA000462988A patent/CA1222654A/en not_active Expired
- 1984-09-13 ZA ZA847226A patent/ZA847226B/xx unknown
- 1984-09-13 DK DK437884A patent/DK437884A/da not_active Application Discontinuation
- 1984-09-14 JP JP59193813A patent/JPS6094063A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5554861A (en) * | 1978-10-16 | 1980-04-22 | Sugiyama Sangyo Kagaku Kenkyusho | Method of treating lecithin |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018500301A (ja) * | 2014-12-02 | 2018-01-11 | アーチャー−ダニエルズ−ミッドランド カンパニー | レシチンの機能性を改善する方法及びその応用 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE32826T1 (de) | 1988-03-15 |
| EP0141442A2 (en) | 1985-05-15 |
| CA1222654A (en) | 1987-06-09 |
| GB8324672D0 (en) | 1983-10-19 |
| DK437884A (da) | 1985-03-15 |
| DK437884D0 (da) | 1984-09-13 |
| ZA847226B (en) | 1986-04-30 |
| DE3469672D1 (en) | 1988-04-14 |
| JPH0355090B2 (enExample) | 1991-08-22 |
| EP0141442A3 (en) | 1985-06-12 |
| EP0141442B1 (en) | 1988-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3782457B2 (ja) | 分別植物油 | |
| US4714571A (en) | Process for purification of phospholipids | |
| US3652397A (en) | Preparation of phosphatides | |
| EP0259495B1 (en) | Process for producing egg yolk lecithin containing a reduced amount of pe and/or containing substantially no impurities | |
| US3563765A (en) | Low cholesterol dried egg yolk and process | |
| EP0703918B1 (en) | Process for obtaining highly purified phosphatidylcholine | |
| Schneider | Fractionation and purification of lecithin | |
| JPH064653B2 (ja) | ホスフアチジルコリンの単離方法 | |
| JPS6336827A (ja) | 界面活性組成物、その製造方法及び食用脂肪含有組成物 | |
| WO1994009015A1 (fr) | Phosphatidylcholine et procede pour sa production | |
| JPS6094063A (ja) | ホスファチジルコリン富有流動化混合物及びその製法 | |
| DE2834999C2 (enExample) | ||
| US8431369B2 (en) | Method for preparation of polyunsaturated fatty acid-containing phosphatidylserine | |
| JPH0665591A (ja) | 脂肪酸エステルの脱色方法 | |
| Smith et al. | Isolation of milk phospholipids and determination of their polyunsaturated fatty acids | |
| Pomeranz et al. | Evaluation of factors affecting lipid binding in wheat flours | |
| JPH05227897A (ja) | レシチン及び該レシチンを含む食用油脂組成物 | |
| US2494726A (en) | Process for treating lipoidal material | |
| JP3009017B2 (ja) | 血中脂質低下剤 | |
| Svennerholm et al. | Chronic sclerosing panencephalitis: II. A neurochemical study | |
| JP2000300186A (ja) | 代謝改善剤 | |
| JP2503567B2 (ja) | レシチンの精製方法 | |
| Eichberg | Lecithin‐its manufacture and use in the fat and oil industry | |
| JPS60155143A (ja) | 天然ロウからの脂肪族高級アルコ−ルの分離法 | |
| Hølmer et al. | Essential fatty acid‐deficient rats: III. Distribution of lipid classes in rat testes after feeding partially hydrogenated oils |