JPS6067433A - マイトマイシン類,多糖類及び抗体の複合体 - Google Patents

マイトマイシン類,多糖類及び抗体の複合体

Info

Publication number
JPS6067433A
JPS6067433A JP17675783A JP17675783A JPS6067433A JP S6067433 A JPS6067433 A JP S6067433A JP 17675783 A JP17675783 A JP 17675783A JP 17675783 A JP17675783 A JP 17675783A JP S6067433 A JPS6067433 A JP S6067433A
Authority
JP
Japan
Prior art keywords
antibody
polysaccharide
group
mitomycins
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17675783A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0570608B2 (cs
Inventor
Mitsuru Hashida
充 橋田
Hitoshi Sezaki
瀬崎 仁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP17675783A priority Critical patent/JPS6067433A/ja
Publication of JPS6067433A publication Critical patent/JPS6067433A/ja
Publication of JPH0570608B2 publication Critical patent/JPH0570608B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP17675783A 1983-09-24 1983-09-24 マイトマイシン類,多糖類及び抗体の複合体 Granted JPS6067433A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17675783A JPS6067433A (ja) 1983-09-24 1983-09-24 マイトマイシン類,多糖類及び抗体の複合体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17675783A JPS6067433A (ja) 1983-09-24 1983-09-24 マイトマイシン類,多糖類及び抗体の複合体

Publications (2)

Publication Number Publication Date
JPS6067433A true JPS6067433A (ja) 1985-04-17
JPH0570608B2 JPH0570608B2 (cs) 1993-10-05

Family

ID=16019277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17675783A Granted JPS6067433A (ja) 1983-09-24 1983-09-24 マイトマイシン類,多糖類及び抗体の複合体

Country Status (1)

Country Link
JP (1) JPS6067433A (cs)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003188A1 (en) * 1988-09-30 1990-04-05 Neorx Corporation Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
US5171563A (en) * 1988-09-30 1992-12-15 Neorx Corporation Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
US6638509B1 (en) 1995-05-10 2003-10-28 Kyowa Hakko Kogyo, Co., Ltd. Toxin conjugates

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003188A1 (en) * 1988-09-30 1990-04-05 Neorx Corporation Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
US5171563A (en) * 1988-09-30 1992-12-15 Neorx Corporation Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
EP0436664B1 (en) * 1988-09-30 1994-11-09 Neorx Corporation Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
US6638509B1 (en) 1995-05-10 2003-10-28 Kyowa Hakko Kogyo, Co., Ltd. Toxin conjugates

Also Published As

Publication number Publication date
JPH0570608B2 (cs) 1993-10-05

Similar Documents

Publication Publication Date Title
CA2097920C (en) Site-specific conjugation of immunoglobulins and detectable labels
Stowell et al. Neoglycoproteins the preparation and application of synthetic glycoproteins
US4046722A (en) Immunological materials
US4401592A (en) Pharmaceutical composition having antitumor activity
US5929049A (en) Polysaccharide conjugates of biomolecules
JPH01230592A (ja) T―抗原決定基を有する免疫吸着剤
JPH0643444B2 (ja) 血液代替物用の新規化合物およびその製造方法
EP0035765B1 (en) A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound
IE872038L (en) 1,4,7,10-tetraazacyclodecane triacrtic acid complexes
JPS63238100A (ja) 抗体複合体の製造方法
JPS61191675A (ja) 巨大分子物質
EP0279862A1 (en) Cytocidal antibody complex and process for its preparation
DE69737298T2 (de) Konjugate von polysacchariden und biomolekülen
HU205135B (en) Process for producing monoclonal antibody nucleoside conjugates
FR2509313A1 (fr) Derives de 3-fucosyl-n-acetyl lactosamine, leur preparation et leurs applications biologiques
JPS59116232A (ja) 細胞毒性複合体及びその製造法
KR0185967B1 (ko) 치료용 약물의 부위 특이적 생체내 활성작용
Delmotte et al. Improved procedures for purification of the Bandeiraea simplicifolia I isolectins and Bandeiraea simplicifolia II lectin by affinity chromatography
JPS6067433A (ja) マイトマイシン類,多糖類及び抗体の複合体
US5672688A (en) Immunoglobulin Fc fragment bound to an alkylating, antibiotic, or antimetabolic antitum or substance
CA1206976A (en) P-glyoxyloylphenylalkanoic acid bis(thiosemicarbazone) derivatives, and their production and use
JPS59134734A (ja) 殺細胞性修飾免疫グロブリン及びその製造方法
CA1079268A (en) Immunological materials
JPS6256137B2 (cs)
SU1070885A1 (ru) Полипептиды на основе @ -лизина в качестве компонентов полипептидного комплекса,полипептидные комплексы на основе @ -лизина в качестве антигенной детерминанты диагностикума и способ получени эритроцитарного диагностикума