JPS6053845A - 血液分離管 - Google Patents
血液分離管Info
- Publication number
- JPS6053845A JPS6053845A JP58161984A JP16198483A JPS6053845A JP S6053845 A JPS6053845 A JP S6053845A JP 58161984 A JP58161984 A JP 58161984A JP 16198483 A JP16198483 A JP 16198483A JP S6053845 A JPS6053845 A JP S6053845A
- Authority
- JP
- Japan
- Prior art keywords
- blood
- agent
- separating
- reagent
- separation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 105
- 239000008280 blood Substances 0.000 title claims abstract description 105
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 84
- 238000000926 separation method Methods 0.000 claims abstract description 33
- 210000000601 blood cell Anatomy 0.000 claims abstract description 24
- 210000002966 serum Anatomy 0.000 claims abstract description 23
- 210000002381 plasma Anatomy 0.000 claims abstract description 20
- 208000007536 Thrombosis Diseases 0.000 claims abstract description 16
- 230000005484 gravity Effects 0.000 claims abstract description 8
- 238000012360 testing method Methods 0.000 claims description 51
- 229940079593 drug Drugs 0.000 claims description 30
- 239000003814 drug Substances 0.000 claims description 30
- 239000000834 fixative Substances 0.000 claims description 14
- 238000004108 freeze drying Methods 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 5
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 5
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 5
- 238000004090 dissolution Methods 0.000 claims description 3
- 238000010828 elution Methods 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 8
- 230000009974 thixotropic effect Effects 0.000 abstract description 4
- 238000005119 centrifugation Methods 0.000 description 5
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 238000010241 blood sampling Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- ZSLUVFAKFWKJRC-IGMARMGPSA-N 232Th Chemical compound [232Th] ZSLUVFAKFWKJRC-IGMARMGPSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 102000007327 Protamines Human genes 0.000 description 1
- 108010007568 Protamines Proteins 0.000 description 1
- 229910052776 Thorium Inorganic materials 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000002981 blocking agent Substances 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000034659 glycolysis Effects 0.000 description 1
- 230000002414 glycolytic effect Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- -1 hydroxypropyl Chemical group 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229950008679 protamine sulfate Drugs 0.000 description 1
- 239000003998 snake venom Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000004441 surface measurement Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- MZQZQKZKTGRQCG-UHFFFAOYSA-J thorium tetrafluoride Chemical compound F[Th](F)(F)F MZQZQKZKTGRQCG-UHFFFAOYSA-J 0.000 description 1
- 230000002345 thrombinlike Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Centrifugal Separators (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58161984A JPS6053845A (ja) | 1983-09-05 | 1983-09-05 | 血液分離管 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58161984A JPS6053845A (ja) | 1983-09-05 | 1983-09-05 | 血液分離管 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6053845A true JPS6053845A (ja) | 1985-03-27 |
| JPH0369069B2 JPH0369069B2 (enrdf_load_stackoverflow) | 1991-10-30 |
Family
ID=15745816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58161984A Granted JPS6053845A (ja) | 1983-09-05 | 1983-09-05 | 血液分離管 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6053845A (enrdf_load_stackoverflow) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4780419A (en) * | 1985-05-10 | 1988-10-25 | Terumo Corporation | Method of inhibiting glycolysis in blood samples |
| JPS6444850A (en) * | 1987-08-14 | 1989-02-17 | Terumo Corp | Blood separation pipe |
| JPH02311761A (ja) * | 1989-05-24 | 1990-12-27 | Robert A Levine | 血液採取装置 |
| JP2011505011A (ja) * | 2007-11-28 | 2011-02-17 | スマート チューブ，インコーポレイテッド | 生体試料の採取、刺激、安定化及び分析のためのデバイス、システム及び方法 |
| JP2014506319A (ja) * | 2010-12-02 | 2014-03-13 | ベクトン・ディキンソン・アンド・カンパニー | 血液安定剤を含む採血用デバイス |
| US8801586B2 (en) | 2008-02-29 | 2014-08-12 | Biomet Biologics, Llc | System and process for separating a material |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US9649579B2 (en) | 2007-04-12 | 2017-05-16 | Hanuman Llc | Buoy suspension fractionation system |
| US9701728B2 (en) | 2008-02-27 | 2017-07-11 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US9897589B2 (en) | 2002-05-24 | 2018-02-20 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US10183042B2 (en) | 2002-05-24 | 2019-01-22 | Biomet Manufacturing, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US10576130B2 (en) | 2013-03-15 | 2020-03-03 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102019121723A1 (de) * | 2019-08-13 | 2021-02-18 | Sarstedt Ag & Co. Kg | Trennkörper und Verfahren zum Trennen von Blutplasma und Blutzellen |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57149964A (en) * | 1981-03-12 | 1982-09-16 | Terumo Corp | Serum separating tube |
| JPS5838536A (ja) * | 1981-08-27 | 1983-03-07 | ベクトン・デイツキンソン・アンド・カンパニ− | 血液収集装置 |
-
1983
- 1983-09-05 JP JP58161984A patent/JPS6053845A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57149964A (en) * | 1981-03-12 | 1982-09-16 | Terumo Corp | Serum separating tube |
| JPS5838536A (ja) * | 1981-08-27 | 1983-03-07 | ベクトン・デイツキンソン・アンド・カンパニ− | 血液収集装置 |
Cited By (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4780419A (en) * | 1985-05-10 | 1988-10-25 | Terumo Corporation | Method of inhibiting glycolysis in blood samples |
| JPS6444850A (en) * | 1987-08-14 | 1989-02-17 | Terumo Corp | Blood separation pipe |
| JPH02311761A (ja) * | 1989-05-24 | 1990-12-27 | Robert A Levine | 血液採取装置 |
| US10183042B2 (en) | 2002-05-24 | 2019-01-22 | Biomet Manufacturing, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US9897589B2 (en) | 2002-05-24 | 2018-02-20 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US10393728B2 (en) | 2002-05-24 | 2019-08-27 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US9649579B2 (en) | 2007-04-12 | 2017-05-16 | Hanuman Llc | Buoy suspension fractionation system |
| JP2011505011A (ja) * | 2007-11-28 | 2011-02-17 | スマート チューブ，インコーポレイテッド | 生体試料の採取、刺激、安定化及び分析のためのデバイス、システム及び方法 |
| US9701728B2 (en) | 2008-02-27 | 2017-07-11 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| US11725031B2 (en) | 2008-02-27 | 2023-08-15 | Biomet Manufacturing, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| US10400017B2 (en) | 2008-02-27 | 2019-09-03 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| US9719063B2 (en) | 2008-02-29 | 2017-08-01 | Biomet Biologics, Llc | System and process for separating a material |
| US8801586B2 (en) | 2008-02-29 | 2014-08-12 | Biomet Biologics, Llc | System and process for separating a material |
| JP2014506319A (ja) * | 2010-12-02 | 2014-03-13 | ベクトン・ディキンソン・アンド・カンパニー | 血液安定剤を含む採血用デバイス |
| US10299714B2 (en) | 2010-12-02 | 2019-05-28 | Becton, Dickinson And Company | Blood collection devices containing blood stabilization agent including variegin or analog thereof and/or a polysulfated disaccharide |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US10441634B2 (en) | 2013-03-15 | 2019-10-15 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US10576130B2 (en) | 2013-03-15 | 2020-03-03 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
| US11957733B2 (en) | 2013-03-15 | 2024-04-16 | Biomet Manufacturing, Llc | Treatment of collagen defects using protein solutions |
| US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0369069B2 (enrdf_load_stackoverflow) | 1991-10-30 |
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