JPS60501409A - ポリヒドロキシ安息香酸誘導体 - Google Patents
ポリヒドロキシ安息香酸誘導体Info
- Publication number
- JPS60501409A JPS60501409A JP59502128A JP50212884A JPS60501409A JP S60501409 A JPS60501409 A JP S60501409A JP 59502128 A JP59502128 A JP 59502128A JP 50212884 A JP50212884 A JP 50212884A JP S60501409 A JPS60501409 A JP S60501409A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- item
- administered
- dihydroxybenzamidoxime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Fats And Perfumes (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Laminated Bodies (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/497,370 US4623659A (en) | 1983-05-23 | 1983-05-23 | Polyhydroxybenzoic acid derivatives |
| US497370 | 1995-06-30 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4039794A Division JPH0578299A (ja) | 1983-05-23 | 1992-02-26 | ポリヒドロキシ安息香酸誘導体とこれを用いた白血病の抑制方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60501409A true JPS60501409A (ja) | 1985-08-29 |
| JPH051780B2 JPH051780B2 (enExample) | 1993-01-11 |
Family
ID=23976584
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59502128A Granted JPS60501409A (ja) | 1983-05-23 | 1984-05-21 | ポリヒドロキシ安息香酸誘導体 |
| JP4039794A Pending JPH0578299A (ja) | 1983-05-23 | 1992-02-26 | ポリヒドロキシ安息香酸誘導体とこれを用いた白血病の抑制方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4039794A Pending JPH0578299A (ja) | 1983-05-23 | 1992-02-26 | ポリヒドロキシ安息香酸誘導体とこれを用いた白血病の抑制方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4623659A (enExample) |
| EP (1) | EP0144396B1 (enExample) |
| JP (2) | JPS60501409A (enExample) |
| KR (1) | KR920004187B1 (enExample) |
| AT (1) | ATE59553T1 (enExample) |
| AU (1) | AU589111B2 (enExample) |
| CA (1) | CA1339221C (enExample) |
| DE (1) | DE3483822D1 (enExample) |
| DK (1) | DK13785D0 (enExample) |
| FI (1) | FI843681A7 (enExample) |
| IT (1) | IT1209548B (enExample) |
| NO (1) | NO843739L (enExample) |
| WO (1) | WO1984004676A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2740133A (en) * | 1951-03-01 | 1956-04-03 | Seng Co | Detachable footboard for a bed |
| US5183828A (en) * | 1983-05-23 | 1993-02-02 | Riet Bartholomeus Van T | Polyhydroxybenzoic acid derivatives |
| US4942253A (en) * | 1983-05-23 | 1990-07-17 | Riet Bartholomeus Van T | Polyhydroxybenzoic acid derivatives |
| EP0610444B1 (en) * | 1991-10-31 | 2003-01-29 | ELFORD, Howard L. | Use of a polyhydroxybenzamide or a derivative thereof in the manufacture of a medicament for treating viral infectious diseases |
| US5350770A (en) * | 1992-07-28 | 1994-09-27 | Elford Howard L | Therapeutic process for the treatment of septic shock |
| US6713517B1 (en) | 1996-03-08 | 2004-03-30 | Oxigene, Inc. | Use of aryl N-substituted carboxamides directly and as radio-and chemosensitizers for killing tumor and cancer cells and novel compounds for such use |
| US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| AU6575498A (en) * | 1997-03-20 | 1998-10-12 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury |
| US6924308B1 (en) * | 1997-07-30 | 2005-08-02 | Howard L. Elford | Therapeutic process for inhibiting NF-κB |
| US6516479B1 (en) * | 2000-06-02 | 2003-02-11 | Burke Mobility Products, Inc. | Foldable rehabilitation bed for accommodating an obese person |
| EP1610611A1 (de) * | 2003-03-26 | 2006-01-04 | Bayer CropScience GmbH | Verwendung von hydroxyaromaten als safener |
| WO2005115405A1 (en) * | 2004-04-28 | 2005-12-08 | Molecules For Health, Inc. | Methods for treating or preventing restenosis and other vascular proliferative disorders |
| US9526707B2 (en) * | 2007-08-13 | 2016-12-27 | Howard L. Elford | Methods for treating or preventing neuroinflammation or autoimmune diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB358279A (en) * | 1930-10-07 | 1931-10-08 | Ig Farbenindustrie Ag | Process for inhibiting the development of micro organisms |
| US2849480A (en) | 1956-10-05 | 1958-08-26 | Kreuchunas Algird | Process for the preparation of 2, 3, 6-trihydroxybenzoic acid and derivatives |
| US3629443A (en) | 1967-11-29 | 1971-12-21 | Orsymonde | Therapeutic composition containing a mandelamidine derivative |
| GB1243186A (en) * | 1967-11-29 | 1971-08-18 | Orsymonde | Improvements in or relating to mandelamidine derivatives |
| US4263322A (en) * | 1979-03-01 | 1981-04-21 | Riet Bartholomeus Van T | Hydroxy benzohydroxamic acids and benzamides |
| US4236322A (en) | 1979-03-15 | 1980-12-02 | Hastings Allen M | Apparatus for and method of drying items by open air and solar energy |
-
1983
- 1983-05-23 US US06/497,370 patent/US4623659A/en not_active Expired - Lifetime
-
1984
- 1984-05-21 AT AT84902270T patent/ATE59553T1/de not_active IP Right Cessation
- 1984-05-21 AU AU30130/84A patent/AU589111B2/en not_active Expired
- 1984-05-21 DE DE8484902270T patent/DE3483822D1/de not_active Expired - Lifetime
- 1984-05-21 EP EP84902270A patent/EP0144396B1/en not_active Expired - Lifetime
- 1984-05-21 JP JP59502128A patent/JPS60501409A/ja active Granted
- 1984-05-21 WO PCT/US1984/000755 patent/WO1984004676A1/en not_active Ceased
- 1984-05-23 KR KR1019840002882A patent/KR920004187B1/ko not_active Expired
- 1984-05-23 IT IT8421068A patent/IT1209548B/it active
- 1984-05-23 CA CA000454910A patent/CA1339221C/en not_active Expired - Lifetime
- 1984-09-19 NO NO843739A patent/NO843739L/no unknown
- 1984-09-20 FI FI843681A patent/FI843681A7/fi not_active Application Discontinuation
-
1985
- 1985-01-11 DK DK13785A patent/DK13785D0/da not_active Application Discontinuation
-
1992
- 1992-02-26 JP JP4039794A patent/JPH0578299A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI843681A0 (fi) | 1984-09-20 |
| DK13785A (da) | 1985-01-11 |
| IT1209548B (it) | 1989-08-30 |
| AU3013084A (en) | 1984-12-18 |
| AU589111B2 (en) | 1989-10-05 |
| WO1984004676A1 (en) | 1984-12-06 |
| KR920004187B1 (ko) | 1992-05-30 |
| ATE59553T1 (de) | 1991-01-15 |
| CA1339221C (en) | 1997-08-05 |
| DK13785D0 (da) | 1985-01-11 |
| EP0144396A1 (en) | 1985-06-19 |
| NO843739L (no) | 1984-12-06 |
| EP0144396B1 (en) | 1991-01-02 |
| FI843681A7 (fi) | 1984-11-24 |
| DE3483822D1 (de) | 1991-02-07 |
| US4623659A (en) | 1986-11-18 |
| IT8421068A0 (it) | 1984-05-23 |
| EP0144396A4 (en) | 1986-08-21 |
| KR850001160A (ko) | 1985-03-16 |
| JPH051780B2 (enExample) | 1993-01-11 |
| JPH0578299A (ja) | 1993-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |