KR920004187B1 - 폴리하이드록시 벤조산 유도체의 제조방법 - Google Patents
폴리하이드록시 벤조산 유도체의 제조방법 Download PDFInfo
- Publication number
- KR920004187B1 KR920004187B1 KR1019840002882A KR840002882A KR920004187B1 KR 920004187 B1 KR920004187 B1 KR 920004187B1 KR 1019840002882 A KR1019840002882 A KR 1019840002882A KR 840002882 A KR840002882 A KR 840002882A KR 920004187 B1 KR920004187 B1 KR 920004187B1
- Authority
- KR
- South Korea
- Prior art keywords
- oxime
- compounds
- ethyl
- solution
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Fats And Perfumes (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Laminated Bodies (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US497,370 | 1983-05-23 | ||
| US06/497,370 US4623659A (en) | 1983-05-23 | 1983-05-23 | Polyhydroxybenzoic acid derivatives |
| US497370 | 1990-03-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR850001160A KR850001160A (ko) | 1985-03-16 |
| KR920004187B1 true KR920004187B1 (ko) | 1992-05-30 |
Family
ID=23976584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019840002882A Expired KR920004187B1 (ko) | 1983-05-23 | 1984-05-23 | 폴리하이드록시 벤조산 유도체의 제조방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4623659A (enExample) |
| EP (1) | EP0144396B1 (enExample) |
| JP (2) | JPS60501409A (enExample) |
| KR (1) | KR920004187B1 (enExample) |
| AT (1) | ATE59553T1 (enExample) |
| AU (1) | AU589111B2 (enExample) |
| CA (1) | CA1339221C (enExample) |
| DE (1) | DE3483822D1 (enExample) |
| DK (1) | DK13785A (enExample) |
| FI (1) | FI843681A7 (enExample) |
| IT (1) | IT1209548B (enExample) |
| NO (1) | NO843739L (enExample) |
| WO (1) | WO1984004676A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2740133A (en) * | 1951-03-01 | 1956-04-03 | Seng Co | Detachable footboard for a bed |
| US4942253A (en) * | 1983-05-23 | 1990-07-17 | Riet Bartholomeus Van T | Polyhydroxybenzoic acid derivatives |
| US5183828A (en) * | 1983-05-23 | 1993-02-02 | Riet Bartholomeus Van T | Polyhydroxybenzoic acid derivatives |
| DE69232911T2 (de) | 1991-10-31 | 2003-11-13 | Inc. Molecules For Health | Verwendung eines polyhydroxybenzamids oder dessen Derivat zur Herstellung eines Medikaments für die Behandlung von viralen Infektionen |
| US5350770A (en) * | 1992-07-28 | 1994-09-27 | Elford Howard L | Therapeutic process for the treatment of septic shock |
| US6713517B1 (en) | 1996-03-08 | 2004-03-30 | Oxigene, Inc. | Use of aryl N-substituted carboxamides directly and as radio-and chemosensitizers for killing tumor and cancer cells and novel compounds for such use |
| US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| WO1998041202A1 (en) * | 1997-03-20 | 1998-09-24 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury |
| US6924308B1 (en) * | 1997-07-30 | 2005-08-02 | Howard L. Elford | Therapeutic process for inhibiting NF-κB |
| US6516479B1 (en) * | 2000-06-02 | 2003-02-11 | Burke Mobility Products, Inc. | Foldable rehabilitation bed for accommodating an obese person |
| AU2004224813B2 (en) * | 2003-03-26 | 2010-11-25 | Bayer Cropscience Ag | Use of aromatic hydroxy compounds as safeners |
| US8029815B2 (en) * | 2004-04-28 | 2011-10-04 | Elford Howard L | Methods for treating or preventing restenosis and other vascular proliferative disorders |
| EP2030615A3 (en) | 2007-08-13 | 2009-12-02 | ELFORD, Howard L. | Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB358279A (en) * | 1930-10-07 | 1931-10-08 | Ig Farbenindustrie Ag | Process for inhibiting the development of micro organisms |
| US2849480A (en) | 1956-10-05 | 1958-08-26 | Kreuchunas Algird | Process for the preparation of 2, 3, 6-trihydroxybenzoic acid and derivatives |
| GB1243186A (en) * | 1967-11-29 | 1971-08-18 | Orsymonde | Improvements in or relating to mandelamidine derivatives |
| US3629443A (en) | 1967-11-29 | 1971-12-21 | Orsymonde | Therapeutic composition containing a mandelamidine derivative |
| US4263322A (en) * | 1979-03-01 | 1981-04-21 | Riet Bartholomeus Van T | Hydroxy benzohydroxamic acids and benzamides |
| US4236322A (en) | 1979-03-15 | 1980-12-02 | Hastings Allen M | Apparatus for and method of drying items by open air and solar energy |
-
1983
- 1983-05-23 US US06/497,370 patent/US4623659A/en not_active Expired - Lifetime
-
1984
- 1984-05-21 DE DE8484902270T patent/DE3483822D1/de not_active Expired - Lifetime
- 1984-05-21 AT AT84902270T patent/ATE59553T1/de not_active IP Right Cessation
- 1984-05-21 AU AU30130/84A patent/AU589111B2/en not_active Expired
- 1984-05-21 WO PCT/US1984/000755 patent/WO1984004676A1/en not_active Ceased
- 1984-05-21 EP EP84902270A patent/EP0144396B1/en not_active Expired - Lifetime
- 1984-05-21 JP JP59502128A patent/JPS60501409A/ja active Granted
- 1984-05-23 IT IT8421068A patent/IT1209548B/it active
- 1984-05-23 KR KR1019840002882A patent/KR920004187B1/ko not_active Expired
- 1984-05-23 CA CA000454910A patent/CA1339221C/en not_active Expired - Lifetime
- 1984-09-19 NO NO843739A patent/NO843739L/no unknown
- 1984-09-20 FI FI843681A patent/FI843681A7/fi not_active Application Discontinuation
-
1985
- 1985-01-11 DK DK13785A patent/DK13785A/da not_active Application Discontinuation
-
1992
- 1992-02-26 JP JP4039794A patent/JPH0578299A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK13785D0 (da) | 1985-01-11 |
| EP0144396A1 (en) | 1985-06-19 |
| JPH0578299A (ja) | 1993-03-30 |
| JPS60501409A (ja) | 1985-08-29 |
| AU589111B2 (en) | 1989-10-05 |
| IT1209548B (it) | 1989-08-30 |
| EP0144396A4 (en) | 1986-08-21 |
| FI843681A0 (fi) | 1984-09-20 |
| US4623659A (en) | 1986-11-18 |
| DK13785A (da) | 1985-01-11 |
| DE3483822D1 (de) | 1991-02-07 |
| AU3013084A (en) | 1984-12-18 |
| NO843739L (no) | 1984-12-06 |
| WO1984004676A1 (en) | 1984-12-06 |
| EP0144396B1 (en) | 1991-01-02 |
| JPH051780B2 (enExample) | 1993-01-11 |
| KR850001160A (ko) | 1985-03-16 |
| ATE59553T1 (de) | 1991-01-15 |
| IT8421068A0 (it) | 1984-05-23 |
| CA1339221C (en) | 1997-08-05 |
| FI843681A7 (fi) | 1984-11-24 |
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| KR920004187B1 (ko) | 폴리하이드록시 벤조산 유도체의 제조방법 | |
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| HU189608B (en) | Process for producing pyridazine derivatives | |
| US5183828A (en) | Polyhydroxybenzoic acid derivatives | |
| US4942253A (en) | Polyhydroxybenzoic acid derivatives | |
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| Taguchi et al. | Studies in Stereochemistry. XII. Mechanism of Racemization in Schiff Bases of D-Methionine Ethyl Ester. | |
| JPH0665668B2 (ja) | フエニルピラジン誘導体および抗血栓剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19840523 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19890523 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19840523 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19910621 Patent event code: PE09021S01D |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19920428 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19920829 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19921210 Patent event code: PR07011E01D |
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| PR1002 | Payment of registration fee |
Payment date: 19921210 End annual number: 3 Start annual number: 1 |
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| PR1001 | Payment of annual fee |
Payment date: 19950329 Start annual number: 4 End annual number: 4 |
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| PR1001 | Payment of annual fee |
Payment date: 19960510 Start annual number: 5 End annual number: 5 |
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| PR1001 | Payment of annual fee |
Payment date: 19970508 Start annual number: 6 End annual number: 6 |
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| PR1001 | Payment of annual fee |
Payment date: 19980522 Start annual number: 7 End annual number: 7 |
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| PR1001 | Payment of annual fee |
Payment date: 19990601 Start annual number: 8 End annual number: 8 |
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| PR1001 | Payment of annual fee |
Payment date: 20000509 Start annual number: 9 End annual number: 9 |
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| PR1001 | Payment of annual fee |
Payment date: 20010525 Start annual number: 10 End annual number: 10 |
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| PR1001 | Payment of annual fee |
Payment date: 20020515 Start annual number: 11 End annual number: 11 |
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| FPAY | Annual fee payment |
Payment date: 20030423 Year of fee payment: 12 |
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| PR1001 | Payment of annual fee |
Payment date: 20030423 Start annual number: 12 End annual number: 12 |
|
| EXPY | Expiration of term | ||
| PC1801 | Expiration of term |