AU6575498A - Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury - Google Patents

Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury

Info

Publication number
AU6575498A
AU6575498A AU65754/98A AU6575498A AU6575498A AU 6575498 A AU6575498 A AU 6575498A AU 65754/98 A AU65754/98 A AU 65754/98A AU 6575498 A AU6575498 A AU 6575498A AU 6575498 A AU6575498 A AU 6575498A
Authority
AU
Australia
Prior art keywords
hydroxybenzoate
cardiotoxicity
extravasation
metabolites
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU65754/98A
Inventor
William Degraff
Anne M. Deluca
Stephen N. Hahn
Murali C Krishna
James B Mitchell
Lawrence Myers
Angelo Russo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
US Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, US Government filed Critical US Department of Health and Human Services
Publication of AU6575498A publication Critical patent/AU6575498A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU65754/98A 1997-03-20 1998-03-19 Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury Abandoned AU6575498A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3937597P 1997-03-20 1997-03-20
US60039375 1997-03-20
PCT/US1998/005554 WO1998041202A1 (en) 1997-03-20 1998-03-19 Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury

Publications (1)

Publication Number Publication Date
AU6575498A true AU6575498A (en) 1998-10-12

Family

ID=21905125

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65754/98A Abandoned AU6575498A (en) 1997-03-20 1998-03-19 Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury

Country Status (2)

Country Link
AU (1) AU6575498A (en)
WO (1) WO1998041202A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1459752A3 (en) 1999-03-12 2007-07-18 TopoTarget A/S Bisdioxopiperazine for the treatment of accidental extravasation of anthracyclines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623659A (en) * 1983-05-23 1986-11-18 Riet Bartholomeus Van T Polyhydroxybenzoic acid derivatives
CA1328279C (en) * 1987-10-01 1994-04-05 F. Hoffmann-La Roche Ag Catechol carboxylic acid derivatives

Also Published As

Publication number Publication date
WO1998041202A1 (en) 1998-09-24

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