JPS6036483A - 置換ベンズイミダゾール - Google Patents

置換ベンズイミダゾール

Info

Publication number
JPS6036483A
JPS6036483A JP59136436A JP13643684A JPS6036483A JP S6036483 A JPS6036483 A JP S6036483A JP 59136436 A JP59136436 A JP 59136436A JP 13643684 A JP13643684 A JP 13643684A JP S6036483 A JPS6036483 A JP S6036483A
Authority
JP
Japan
Prior art keywords
formula
compound
preparation example
product
chart
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP59136436A
Other languages
English (en)
Japanese (ja)
Inventor
ジヨン・チヤールズ・シー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of JPS6036483A publication Critical patent/JPS6036483A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP59136436A 1983-07-01 1984-06-30 置換ベンズイミダゾール Pending JPS6036483A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51046883A 1983-07-01 1983-07-01
US510468 1983-07-01

Publications (1)

Publication Number Publication Date
JPS6036483A true JPS6036483A (ja) 1985-02-25

Family

ID=24030850

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59136436A Pending JPS6036483A (ja) 1983-07-01 1984-06-30 置換ベンズイミダゾール

Country Status (15)

Country Link
EP (1) EP0130729A3 (enExample)
JP (1) JPS6036483A (enExample)
KR (1) KR890000881B1 (enExample)
AU (1) AU573744B2 (enExample)
CA (1) CA1259070A (enExample)
DK (1) DK321884A (enExample)
ES (1) ES8601914A1 (enExample)
FI (1) FI83514C (enExample)
GR (1) GR81445B (enExample)
IL (1) IL72159A (enExample)
MX (1) MX161283A (enExample)
NO (1) NO164472C (enExample)
NZ (1) NZ208553A (enExample)
PH (1) PH20625A (enExample)
ZA (1) ZA844953B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452782A (en) * 1987-05-19 1989-02-28 Shionogi & Co Thienopyridine derivative and antiulcer agent

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0174717B1 (en) 1984-07-06 1992-01-22 FISONS plc Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
DE3579436D1 (de) * 1984-12-18 1990-10-04 Otsuka Pharma Co Ltd Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen.
AU5768886A (en) 1985-05-24 1986-11-27 G.D. Searle & Co. 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
FI864138A7 (fi) * 1985-10-16 1987-04-17 Fisons Plc Heterocykliska blandningar.
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
ES2031853T3 (es) * 1986-07-01 1993-01-01 Shionogi Seiyaku Kabushiki Kaisha Un procedimiento para preparar derivados de isoquinolina sustituidos.
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
US4839365A (en) * 1987-05-19 1989-06-13 Shinogi & Co., Ltd. Thienopyridine derivatives useful in treating gastric ulcers
AU2395095A (en) 1994-04-29 1995-11-29 G.D. Searle & Co. Method of using (h+/k+) atpase inhibitors as antiviral agents
WO1997000875A1 (en) * 1995-06-21 1997-01-09 Korea Research Institute Of Chemical Technology Benzimidazole derivatives containing fused pyridine
ES2236628T3 (es) * 1995-09-21 2005-07-16 Pharma Pass Ii Llc Composicion farmaceutica que contiene un omeprazol labil de acido, y procedimiento para su preparacion.
RU2217424C2 (ru) * 2001-12-14 2003-11-27 Федеральное государственное унитарное предприятие Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" Способ получения 5-метокси-2-меркаптобензимидазола
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59181277A (ja) * 1983-02-11 1984-10-15 アクチエボラゲツト・ヘツスレ 新規な薬理学的に活性な化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
ZA825106B (en) * 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59181277A (ja) * 1983-02-11 1984-10-15 アクチエボラゲツト・ヘツスレ 新規な薬理学的に活性な化合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452782A (en) * 1987-05-19 1989-02-28 Shionogi & Co Thienopyridine derivative and antiulcer agent

Also Published As

Publication number Publication date
EP0130729A2 (en) 1985-01-09
KR850001201A (ko) 1985-03-16
NO164472B (no) 1990-07-02
FI83514B (fi) 1991-04-15
FI842631A7 (fi) 1985-01-02
PH20625A (en) 1987-03-06
MX161283A (es) 1990-08-28
GR81445B (enExample) 1984-12-11
ZA844953B (en) 1985-02-27
EP0130729A3 (en) 1986-08-06
CA1259070A (en) 1989-09-05
KR890000881B1 (ko) 1989-04-12
FI83514C (fi) 1991-07-25
IL72159A (en) 1987-12-31
NZ208553A (en) 1987-07-31
NO164472C (no) 1990-10-10
NO842645L (no) 1985-01-02
DK321884A (da) 1985-01-02
ES533853A0 (es) 1985-12-01
AU2999684A (en) 1985-01-03
FI842631A0 (fi) 1984-06-29
AU573744B2 (en) 1988-06-23
IL72159A0 (en) 1984-10-31
ES8601914A1 (es) 1985-12-01
DK321884D0 (da) 1984-06-29

Similar Documents

Publication Publication Date Title
JPS6036483A (ja) 置換ベンズイミダゾール
JP3313708B2 (ja) イミダゾ〔４，５−ｃ〕キノリン−４−アミンの製法
US4628098A (en) 2-[2-pyridylmethylthio-(sulfinyl)]benzimidazoles
EP0248523B1 (en) Pyrazoles
RU2049779C1 (ru) Производные 4-аминофенола или их n-алкильные или солевые производные, проявляющие противовоспалительную активность
DE69810938T2 (de) Pyrazolderivate und sie enthaltende cox-inhibitoren
PT94114B (pt) Processo para a preparacao de derivados de aza-indenos e de composicoes farmaceuticas que os contem
EP0130795A2 (en) Carboxylic acid derivatives useful for inhibiting the degradation of cartilage
EP0175464B1 (en) Benzimidazole derivatives and their production
EP0150586B1 (en) 2-(pyridylmethylthio)benzimidazoles and 2-(pyridylmethylsulfinyl)benzimidazoles
EP0178035A1 (en) Anti-inflammatory 1,N-diarylpyrazol-3-amines, compositions containing them and processes for their preparation
IE46507B1 (en) 5-(4-(diarylmethyl)-1-piperazinylalkyl) benzimidazole derivatives
JPH01211567A (ja) 新規なスルホンアミド化合物
NZ250580A (en) 3-(hetero)aryloxymorphinan derivatives and their use in the manufacture of medicaments
PT88781B (pt) Processo para a preparacao de tetralinas, cromanos e compostos relacionados substituiidos, uteis no tratamento da asma
DD258984A5 (de) Verfahren zur herstellung neuer heterozyklischer carboxamid-derivate
SI9300191A (sl) Novi amidoalkil- in imidoalkil-piperazini
JPS6129342B2 (enExample)
JPS62277392A (ja) スルフエンアミド誘導体およびその製造法
JP3901239B2 (ja) アリールアルカン誘導体
US4292323A (en) Phenyl-1,2,3,4-tetrahydrocarbazoles and use thereof
NO170931B (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 2-alkylbenzimidazolderivater
US4680398A (en) Pyrazolo[1,5-a]pyridines and benzimidazoles, useful as antiallergic agents
JPS6353984B2 (enExample)
US3300506A (en) 1-indolyl substituted-2-pyridyl-ethanes