NO842645L - Fremgangsmaate ved fremstilling av substituerte 2-(monokondenserte(3,4-, 4,5- og 5,6-)pyridylalkylensulfinyl)-benzimidazoler - Google Patents

Fremgangsmaate ved fremstilling av substituerte 2-(monokondenserte(3,4-, 4,5- og 5,6-)pyridylalkylensulfinyl)-benzimidazoler

Info

Publication number
NO842645L
NO842645L NO842645A NO842645A NO842645L NO 842645 L NO842645 L NO 842645L NO 842645 A NO842645 A NO 842645A NO 842645 A NO842645 A NO 842645A NO 842645 L NO842645 L NO 842645L
Authority
NO
Norway
Prior art keywords
pyridylalkylensulphinyl
benzimidazoles
condensed
mono
substituted
Prior art date
Application number
NO842645A
Other languages
English (en)
Other versions
NO164472C (no
NO164472B (no
Inventor
John Charles Sih
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO842645L publication Critical patent/NO842645L/no
Publication of NO164472B publication Critical patent/NO164472B/no
Publication of NO164472C publication Critical patent/NO164472C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO842645A 1983-07-01 1984-06-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte 2-(monokondenserte (3,4- og 5,6)-pyridylalkylensulfinyl)-benzimidazoler. NO164472C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51046883A 1983-07-01 1983-07-01

Publications (3)

Publication Number Publication Date
NO842645L true NO842645L (no) 1985-01-02
NO164472B NO164472B (no) 1990-07-02
NO164472C NO164472C (no) 1990-10-10

Family

ID=24030850

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842645A NO164472C (no) 1983-07-01 1984-06-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte 2-(monokondenserte (3,4- og 5,6)-pyridylalkylensulfinyl)-benzimidazoler.

Country Status (15)

Country Link
EP (1) EP0130729A3 (no)
JP (1) JPS6036483A (no)
KR (1) KR890000881B1 (no)
AU (1) AU573744B2 (no)
CA (1) CA1259070A (no)
DK (1) DK321884A (no)
ES (1) ES8601914A1 (no)
FI (1) FI83514C (no)
GR (1) GR81445B (no)
IL (1) IL72159A (no)
MX (1) MX161283A (no)
NO (1) NO164472C (no)
NZ (1) NZ208553A (no)
PH (1) PH20625A (no)
ZA (1) ZA844953B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3585252D1 (de) 1984-07-06 1992-03-05 Fisons Plc Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen.
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
EP0187977B1 (en) * 1984-12-18 1990-08-29 Otsuka Pharmaceutical Co., Ltd. Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same
AU5768886A (en) 1985-05-24 1986-11-27 G.D. Searle & Co. 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
FI864138A (fi) * 1985-10-16 1987-04-17 Fisons Plc Heterocykliska blandningar.
ES2038612T3 (es) * 1986-03-28 1993-08-01 Otsuka Pharmaceutical Co., Ltd. Compuestos de hidroquinolina, composiciones que los contienen y procedimientos para prepararlas.
ES2031853T3 (es) * 1986-07-01 1993-01-01 Shionogi Seiyaku Kabushiki Kaisha Un procedimiento para preparar derivados de isoquinolina sustituidos.
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
JPS6452782A (en) * 1987-05-19 1989-02-28 Shionogi & Co Thienopyridine derivative and antiulcer agent
US4839365A (en) * 1987-05-19 1989-06-13 Shinogi & Co., Ltd. Thienopyridine derivatives useful in treating gastric ulcers
WO1995029897A1 (en) * 1994-04-29 1995-11-09 G.D. Searle & Co. METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS
WO1997000875A1 (en) * 1995-06-21 1997-01-09 Korea Research Institute Of Chemical Technology Benzimidazole derivatives containing fused pyridine
DK1308159T3 (da) * 1995-09-21 2005-02-14 Pharma Pass Ii Llc Farmaceutisk sammensætning indeholdende en syre-labil omeprazol og fremgangsmåde til fremstilling deraf
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
ZA825106B (en) * 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds

Also Published As

Publication number Publication date
MX161283A (es) 1990-08-28
AU573744B2 (en) 1988-06-23
FI83514B (fi) 1991-04-15
ES533853A0 (es) 1985-12-01
IL72159A (en) 1987-12-31
JPS6036483A (ja) 1985-02-25
FI83514C (fi) 1991-07-25
GR81445B (no) 1984-12-11
NO164472C (no) 1990-10-10
DK321884A (da) 1985-01-02
FI842631A0 (fi) 1984-06-29
ZA844953B (en) 1985-02-27
FI842631A (fi) 1985-01-02
KR850001201A (ko) 1985-03-16
EP0130729A2 (en) 1985-01-09
PH20625A (en) 1987-03-06
NZ208553A (en) 1987-07-31
KR890000881B1 (ko) 1989-04-12
ES8601914A1 (es) 1985-12-01
AU2999684A (en) 1985-01-03
NO164472B (no) 1990-07-02
EP0130729A3 (en) 1986-08-06
IL72159A0 (en) 1984-10-31
DK321884D0 (da) 1984-06-29
CA1259070A (en) 1989-09-05

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