JPS6026106B2 - アミノアルキリデンアミノ−１，４−ジヒドロピリジン及びその製造法 - Google Patents

アミノアルキリデンアミノ−１，４−ジヒドロピリジン及びその製造法

Info

Publication number
JPS6026106B2
JPS6026106B2 JP52103283A JP10328377A JPS6026106B2 JP S6026106 B2 JPS6026106 B2 JP S6026106B2 JP 52103283 A JP52103283 A JP 52103283A JP 10328377 A JP10328377 A JP 10328377A JP S6026106 B2 JPS6026106 B2 JP S6026106B2
Authority
JP
Japan
Prior art keywords
dihydropyridine
methyl
amino
mmol
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52103283A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5331670A (en
Inventor
エグベルト・ベヒンガ−
フリ−ドリツヒ・ボザ−ト
ホルスト・マイヤ−
ブルフ・フア−タ−
アレント・ハイゼ
スタニスラフ・カツダ
クルト・ステツペル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS5331670A publication Critical patent/JPS5331670A/ja
Publication of JPS6026106B2 publication Critical patent/JPS6026106B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP52103283A 1976-09-01 1977-08-30 アミノアルキリデンアミノ−１，４−ジヒドロピリジン及びその製造法 Expired JPS6026106B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762639257 DE2639257A1 (de) 1976-09-01 1976-09-01 Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2639257.4 1976-09-01

Publications (2)

Publication Number Publication Date
JPS5331670A JPS5331670A (en) 1978-03-25
JPS6026106B2 true JPS6026106B2 (ja) 1985-06-21

Family

ID=5986848

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52103283A Expired JPS6026106B2 (ja) 1976-09-01 1977-08-30 アミノアルキリデンアミノ−１，４−ジヒドロピリジン及びその製造法

Country Status (12)

Country Link
US (1) US4146627A (enExample)
JP (1) JPS6026106B2 (enExample)
AT (1) AT364359B (enExample)
BE (1) BE858269A (enExample)
CH (1) CH634053A5 (enExample)
DE (1) DE2639257A1 (enExample)
ES (1) ES461994A1 (enExample)
FI (1) FI60862C (enExample)
FR (1) FR2363554A1 (enExample)
GB (1) GB1554495A (enExample)
NL (1) NL7709508A (enExample)
SE (1) SE7709797L (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835069A1 (de) * 1978-08-10 1980-02-21 Bayer Ag N-amino-3,4,5-trihydroxypiperidine, ihre herstellung und verwendung
NZ193167A (en) 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS58131982A (ja) * 1982-02-01 1983-08-06 Tokyo Tanabe Co Ltd 新規なる１．４−ジヒドロピリジン誘導体
US4419518A (en) * 1982-07-26 1983-12-06 Tokyo Tanabe Co. L.T.D. 1,4-Dihydropyridine derivatives
US4520131A (en) * 1983-03-03 1985-05-28 Usv Pharmaceutical Antihypertensive N-substituted 1,4-dihydropyridines
GR851819B (enExample) * 1984-08-17 1985-11-26 Wyeth John & Brother Ltd
US4652573A (en) * 1985-03-14 1987-03-24 Nelson Research & Development Co. Calcium antagonist N-hetero ester 1,4-dihydropyridines
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
US5220027A (en) * 1987-04-14 1993-06-15 Sumitomo Chemical Company, Limited Sulfone-containing azamethide compounds with a nitrogen-containing aromatic ring of nitrogen containing aliphatic
US5028708A (en) * 1987-04-14 1991-07-02 Sumitomo Chemical Company, Limited Azamethinyl quinoline derivatives
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
DE4313696A1 (de) * 1993-04-27 1994-11-03 Bayer Ag 2-Amino-4-heteroaryl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
JP3394215B2 (ja) 1999-07-29 2003-04-07 株式会社 日立インダストリイズ フィルム減圧貼り合わせ装置
CN1280674C (zh) * 2001-03-29 2006-10-18 日立化成工业株式会社 电路形成用感光性膜及印刷配线板的制造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946026A (en) * 1972-03-06 1976-03-23 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
DE2239815C2 (de) * 1972-08-12 1983-02-10 Bayer Ag, 5090 Leverkusen 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof

Also Published As

Publication number Publication date
ATA629677A (de) 1981-03-15
FI60862B (fi) 1981-12-31
US4146627A (en) 1979-03-27
FI772569A7 (fi) 1978-03-02
FR2363554B1 (enExample) 1980-08-08
GB1554495A (en) 1979-10-24
FR2363554A1 (fr) 1978-03-31
JPS5331670A (en) 1978-03-25
CH634053A5 (de) 1983-01-14
AT364359B (de) 1981-10-12
NL7709508A (nl) 1978-03-03
SE7709797L (sv) 1978-03-02
BE858269A (fr) 1978-02-28
FI60862C (fi) 1982-04-13
DE2639257A1 (de) 1978-03-02
ES461994A1 (es) 1978-12-01

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