JPS60232098A - エステル分解酵素及び／又は蛋白質分解酵素の検出用試薬 - Google Patents
エステル分解酵素及び／又は蛋白質分解酵素の検出用試薬Info
- Publication number
- JPS60232098A JPS60232098A JP60071263A JP7126385A JPS60232098A JP S60232098 A JPS60232098 A JP S60232098A JP 60071263 A JP60071263 A JP 60071263A JP 7126385 A JP7126385 A JP 7126385A JP S60232098 A JPS60232098 A JP S60232098A
- Authority
- JP
- Japan
- Prior art keywords
- group
- reagent
- amino acid
- ester
- reagent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 238000001035 drying Methods 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 125000004185 ester group Chemical group 0.000 description 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012065 filter cake Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 150000004676 glycans Polymers 0.000 description 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 229940025770 heparinoids Drugs 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 229940097275 indigo Drugs 0.000 description 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
- 229910001412 inorganic anion Inorganic materials 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Chemical class 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 150000002482 oligosaccharides Polymers 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000002891 organic anions Chemical class 0.000 description 1
- 229960003104 ornithine Drugs 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 229920000833 poly(n-hexyl isocyanate) polymer Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 229920001290 polyvinyl ester Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 125000000565 sulfonamide group Chemical group 0.000 description 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000003021 water soluble solvent Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3413118.3 | 1984-04-06 | ||
| DE19843413118 DE3413118A1 (de) | 1984-04-06 | 1984-04-06 | Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60232098A true JPS60232098A (ja) | 1985-11-18 |
| JPH0550279B2 JPH0550279B2 (enExample) | 1993-07-28 |
Family
ID=6232927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60071263A Granted JPS60232098A (ja) | 1984-04-06 | 1985-04-05 | エステル分解酵素及び／又は蛋白質分解酵素の検出用試薬 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4758508A (enExample) |
| EP (1) | EP0158225B1 (enExample) |
| JP (1) | JPS60232098A (enExample) |
| AT (1) | ATE73500T1 (enExample) |
| AU (1) | AU560315B2 (enExample) |
| CA (1) | CA1263591C (enExample) |
| DE (2) | DE3413118A1 (enExample) |
| DK (1) | DK154685A (enExample) |
| ES (1) | ES8607400A1 (enExample) |
| FI (1) | FI86204C (enExample) |
| IE (1) | IE58047B1 (enExample) |
| IL (1) | IL74646A (enExample) |
| NO (1) | NO171072C (enExample) |
| ZA (1) | ZA852269B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998046787A1 (fr) * | 1997-04-11 | 1998-10-22 | Fuji Photo Film Co., Ltd. | Procede de dosage d'enzymes |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5316906A (en) * | 1991-08-23 | 1994-05-31 | Molecular Probes, Inc. | Enzymatic analysis using substrates that yield fluorescent precipitates |
| US5981206A (en) * | 1992-05-20 | 1999-11-09 | Johnson & Johnson Clinical Diagnostic Systems, Inc. | Dry analytical element and method for the detection of prostatic acid phosphatase |
| EP0695424A1 (en) * | 1993-04-19 | 1996-02-07 | E.I. Du Pont De Nemours And Company | A method for improving the signal to noise ratio of an immunoassay |
| US5776780A (en) * | 1993-05-28 | 1998-07-07 | Chimera Research & Chemical, Inc. | Method for quantitatively measuring white blood cells esterase activity in urine |
| US6551791B1 (en) * | 1995-12-21 | 2003-04-22 | University Of Florida | Rapid diagnostic method for distinguishing allergies and infections and nasal secretion collection unit |
| US5910421A (en) * | 1995-12-21 | 1999-06-08 | University Of Florida | Rapid diagnostic method for distinguishing allergies and infections |
| CA2350404C (en) | 1998-11-11 | 2010-04-06 | Ronald E. Wheeler | Detection of prostatitis |
| US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
| US6528652B1 (en) * | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
| US6709868B2 (en) * | 2002-05-20 | 2004-03-23 | Portascience Inc. | Method and apparatus for measuring white blood cell count |
| US7727206B2 (en) * | 2005-12-27 | 2010-06-01 | Gorres Geoffrey H | Device for monitoring a patient for a urinary tract infection |
| US20080057596A1 (en) * | 2006-08-30 | 2008-03-06 | Wai Tak Law | Colorimetric determination of somatic cell count in milk |
| US20100047848A1 (en) * | 2006-08-30 | 2010-02-25 | Wai Tak Law | Colorimetric determination of somatic cell count in milk |
| EP2382466B1 (en) | 2008-12-30 | 2016-03-09 | Children's Medical Center Corporation | Method of predicting acute appendicitis |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55108300A (en) * | 1979-02-14 | 1980-08-20 | Boehringer Mannheim Gmbh | Diagnostic agent for detecting ester decomposing enzyme and or ppotein hydrolysing enzyme in biological fluid and production thereof |
| JPS56138153A (en) * | 1980-02-16 | 1981-10-28 | Boehringer Mannheim Gmbh | Amino acid ester and peptide ester of leuco- indoaniline, manufacture and drug containing same for detecting proteinase |
| JPS578798A (en) * | 1980-05-09 | 1982-01-18 | Boehringer Mannheim Gmbh | Detecting agent of ester decomposing and / or protein decomposing enzyme and base medium thereof |
| JPS581920A (ja) * | 1981-06-27 | 1983-01-07 | 住友電気工業株式会社 | 金属被ケ−ブル及びその防食処理方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT324282B (de) * | 1972-06-19 | 1975-08-25 | Boehringer Mannheim Gmbh | Verfahren und reagens zur bestimmung von triglyceriden |
| US4212939A (en) * | 1977-11-22 | 1980-07-15 | The University Of Alabama | Substrate solution for carboxylic ester hydrolase determination |
| DE2826965A1 (de) * | 1978-06-20 | 1980-01-17 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten und dafuer geeignete chromogene |
| DE2836644A1 (de) * | 1978-08-22 | 1980-03-06 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten und dafuer geeignete chromogene |
| DE2904305C2 (de) * | 1979-02-05 | 1981-07-02 | Boehringer Mannheim Gmbh, 6800 Mannheim | Reagens zur Lipasebestimmung und Verfahren zu seiner Herstellung |
| US4499185A (en) * | 1982-05-17 | 1985-02-12 | Miles Laboratories, Inc. | Test for esterase activity in a liquid sample |
| DE3323245A1 (de) * | 1983-06-28 | 1985-01-10 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren und reagenz zur bestimmung von (alpha)-amylase |
| EP0134291B1 (de) * | 1983-09-07 | 1986-08-13 | American Hospital Supply Corporation | Rekonstituierbares Trockenreagenz für diagnostische Zwecke und Verfahren zu seiner Herstellung |
-
1984
- 1984-04-06 DE DE19843413118 patent/DE3413118A1/de not_active Withdrawn
-
1985
- 1985-03-11 US US06/710,423 patent/US4758508A/en not_active Expired - Lifetime
- 1985-03-19 CA CA476900A patent/CA1263591C/en not_active Expired
- 1985-03-19 IL IL74646A patent/IL74646A/xx unknown
- 1985-03-21 NO NO851142A patent/NO171072C/no unknown
- 1985-03-26 AU AU40362/85A patent/AU560315B2/en not_active Ceased
- 1985-03-26 ZA ZA852269A patent/ZA852269B/xx unknown
- 1985-03-27 EP EP85103672A patent/EP0158225B1/de not_active Expired - Lifetime
- 1985-03-27 AT AT85103672T patent/ATE73500T1/de not_active IP Right Cessation
- 1985-03-27 DE DE8585103672T patent/DE3585548D1/de not_active Expired - Lifetime
- 1985-04-02 ES ES541869A patent/ES8607400A1/es not_active Expired
- 1985-04-03 FI FI851352A patent/FI86204C/fi not_active IP Right Cessation
- 1985-04-03 DK DK154685A patent/DK154685A/da not_active Application Discontinuation
- 1985-04-04 IE IE86885A patent/IE58047B1/en not_active IP Right Cessation
- 1985-04-05 JP JP60071263A patent/JPS60232098A/ja active Granted
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55108300A (en) * | 1979-02-14 | 1980-08-20 | Boehringer Mannheim Gmbh | Diagnostic agent for detecting ester decomposing enzyme and or ppotein hydrolysing enzyme in biological fluid and production thereof |
| JPS56138153A (en) * | 1980-02-16 | 1981-10-28 | Boehringer Mannheim Gmbh | Amino acid ester and peptide ester of leuco- indoaniline, manufacture and drug containing same for detecting proteinase |
| JPS578798A (en) * | 1980-05-09 | 1982-01-18 | Boehringer Mannheim Gmbh | Detecting agent of ester decomposing and / or protein decomposing enzyme and base medium thereof |
| JPS581920A (ja) * | 1981-06-27 | 1983-01-07 | 住友電気工業株式会社 | 金属被ケ−ブル及びその防食処理方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998046787A1 (fr) * | 1997-04-11 | 1998-10-22 | Fuji Photo Film Co., Ltd. | Procede de dosage d'enzymes |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1263591A (en) | 1989-12-05 |
| IL74646A (en) | 1989-06-30 |
| US4758508A (en) | 1988-07-19 |
| FI851352L (fi) | 1985-10-07 |
| FI86204C (fi) | 1992-07-27 |
| DE3413118A1 (de) | 1985-10-24 |
| DE3585548D1 (de) | 1992-04-16 |
| NO171072C (no) | 1993-01-20 |
| DK154685D0 (da) | 1985-04-03 |
| IE850868L (en) | 1985-10-06 |
| CA1263591C (en) | 1989-12-05 |
| AU560315B2 (en) | 1987-04-02 |
| NO171072B (no) | 1992-10-12 |
| AU4036285A (en) | 1985-10-10 |
| ZA852269B (en) | 1985-11-27 |
| EP0158225A3 (en) | 1987-10-21 |
| EP0158225A2 (de) | 1985-10-16 |
| ES8607400A1 (es) | 1986-06-01 |
| FI86204B (fi) | 1992-04-15 |
| ATE73500T1 (de) | 1992-03-15 |
| JPH0550279B2 (enExample) | 1993-07-28 |
| IE58047B1 (en) | 1993-06-16 |
| FI851352A0 (fi) | 1985-04-03 |
| NO851142L (no) | 1985-10-07 |
| DK154685A (da) | 1985-10-07 |
| EP0158225B1 (de) | 1992-03-11 |
| IL74646A0 (en) | 1985-06-30 |
| ES541869A0 (es) | 1986-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| EXPY | Cancellation because of completion of term |