CA1263591C - METHOD OF ANALYSIS AND AGENTS FOR THE DETECTION OF ESTEROLYTIC AND (OR) PROTEOLYTIC ENZYMES - Google Patents
METHOD OF ANALYSIS AND AGENTS FOR THE DETECTION OF ESTEROLYTIC AND (OR) PROTEOLYTIC ENZYMESInfo
- Publication number
- CA1263591C CA1263591C CA476900A CA476900A CA1263591C CA 1263591 C CA1263591 C CA 1263591C CA 476900 A CA476900 A CA 476900A CA 476900 A CA476900 A CA 476900A CA 1263591 C CA1263591 C CA 1263591C
- Authority
- CA
- Canada
- Prior art keywords
- esterolytic
- detection
- agents
- ester
- proteolytic enzymes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 102000035195 Peptidases Human genes 0.000 title abstract 2
- 108091005804 Peptidases Proteins 0.000 title abstract 2
- 230000000058 esterolytic effect Effects 0.000 title abstract 2
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- -1 aminoacid ester Chemical class 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229940088598 enzyme Drugs 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- DTQVDTLACAAQTR-UHFFFAOYSA-M Trifluoroacetate Chemical compound [O-]C(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-M 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 125000002577 pseudohalo group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA476900A CA1263591C (en) | 1984-04-06 | 1985-03-19 | METHOD OF ANALYSIS AND AGENTS FOR THE DETECTION OF ESTEROLYTIC AND (OR) PROTEOLYTIC ENZYMES |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843413118 DE3413118A1 (de) | 1984-04-06 | 1984-04-06 | Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme |
| DELEA22901 | 1984-04-06 | ||
| CA476900A CA1263591C (en) | 1984-04-06 | 1985-03-19 | METHOD OF ANALYSIS AND AGENTS FOR THE DETECTION OF ESTEROLYTIC AND (OR) PROTEOLYTIC ENZYMES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA1263591A CA1263591A (en) | 1989-12-05 |
| CA1263591C true CA1263591C (en) | 1989-12-05 |
Family
ID=6232927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA476900A Expired CA1263591C (en) | 1984-04-06 | 1985-03-19 | METHOD OF ANALYSIS AND AGENTS FOR THE DETECTION OF ESTEROLYTIC AND (OR) PROTEOLYTIC ENZYMES |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4758508A (enExample) |
| EP (1) | EP0158225B1 (enExample) |
| JP (1) | JPS60232098A (enExample) |
| AT (1) | ATE73500T1 (enExample) |
| AU (1) | AU560315B2 (enExample) |
| CA (1) | CA1263591C (enExample) |
| DE (2) | DE3413118A1 (enExample) |
| DK (1) | DK154685A (enExample) |
| ES (1) | ES8607400A1 (enExample) |
| FI (1) | FI86204C (enExample) |
| IE (1) | IE58047B1 (enExample) |
| IL (1) | IL74646A (enExample) |
| NO (1) | NO171072C (enExample) |
| ZA (1) | ZA852269B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5316906A (en) * | 1991-08-23 | 1994-05-31 | Molecular Probes, Inc. | Enzymatic analysis using substrates that yield fluorescent precipitates |
| US5981206A (en) * | 1992-05-20 | 1999-11-09 | Johnson & Johnson Clinical Diagnostic Systems, Inc. | Dry analytical element and method for the detection of prostatic acid phosphatase |
| WO1994024558A1 (en) * | 1993-04-19 | 1994-10-27 | E.I. Du Pont De Nemours And Company | A method for improving the signal to noise ratio of an immunoassay |
| US5776780A (en) * | 1993-05-28 | 1998-07-07 | Chimera Research & Chemical, Inc. | Method for quantitatively measuring white blood cells esterase activity in urine |
| US5910421A (en) * | 1995-12-21 | 1999-06-08 | University Of Florida | Rapid diagnostic method for distinguishing allergies and infections |
| US6551791B1 (en) | 1995-12-21 | 2003-04-22 | University Of Florida | Rapid diagnostic method for distinguishing allergies and infections and nasal secretion collection unit |
| WO1998046787A1 (fr) * | 1997-04-11 | 1998-10-22 | Fuji Photo Film Co., Ltd. | Procede de dosage d'enzymes |
| CA2350404C (en) | 1998-11-11 | 2010-04-06 | Ronald E. Wheeler | Detection of prostatitis |
| US6528652B1 (en) | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
| US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
| US6709868B2 (en) * | 2002-05-20 | 2004-03-23 | Portascience Inc. | Method and apparatus for measuring white blood cell count |
| US7727206B2 (en) * | 2005-12-27 | 2010-06-01 | Gorres Geoffrey H | Device for monitoring a patient for a urinary tract infection |
| US20100047848A1 (en) * | 2006-08-30 | 2010-02-25 | Wai Tak Law | Colorimetric determination of somatic cell count in milk |
| US20080057596A1 (en) * | 2006-08-30 | 2008-03-06 | Wai Tak Law | Colorimetric determination of somatic cell count in milk |
| EP3913367A1 (en) | 2008-12-30 | 2021-11-24 | Children's Medical Center Corporation | Method of predicting acute appendicitis |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT324282B (de) * | 1972-06-19 | 1975-08-25 | Boehringer Mannheim Gmbh | Verfahren und reagens zur bestimmung von triglyceriden |
| US4212939A (en) * | 1977-11-22 | 1980-07-15 | The University Of Alabama | Substrate solution for carboxylic ester hydrolase determination |
| DE2826965A1 (de) * | 1978-06-20 | 1980-01-17 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten und dafuer geeignete chromogene |
| DE2836644A1 (de) * | 1978-08-22 | 1980-03-06 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten und dafuer geeignete chromogene |
| DE2904305C2 (de) * | 1979-02-05 | 1981-07-02 | Boehringer Mannheim Gmbh, 6800 Mannheim | Reagens zur Lipasebestimmung und Verfahren zu seiner Herstellung |
| DE2905531A1 (de) * | 1979-02-14 | 1981-01-08 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten |
| DE3005845A1 (de) * | 1980-02-16 | 1981-09-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Aminosaeure- und peptidester von leuko-indoanilinen, verfahren zu deren herstellung sowie diese verbindungen enthaltende mittel zum nachweis proteolytischer enzyme |
| DE3017721A1 (de) * | 1980-05-09 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Mittel zum nachweis esterolytischer und/oder proteolytischer enzyme und dafuer geeignete substrate |
| JPS581920A (ja) * | 1981-06-27 | 1983-01-07 | 住友電気工業株式会社 | 金属被ケ−ブル及びその防食処理方法 |
| US4499185A (en) * | 1982-05-17 | 1985-02-12 | Miles Laboratories, Inc. | Test for esterase activity in a liquid sample |
| DE3323245A1 (de) * | 1983-06-28 | 1985-01-10 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren und reagenz zur bestimmung von (alpha)-amylase |
| EP0134291B1 (de) * | 1983-09-07 | 1986-08-13 | American Hospital Supply Corporation | Rekonstituierbares Trockenreagenz für diagnostische Zwecke und Verfahren zu seiner Herstellung |
-
1984
- 1984-04-06 DE DE19843413118 patent/DE3413118A1/de not_active Withdrawn
-
1985
- 1985-03-11 US US06/710,423 patent/US4758508A/en not_active Expired - Lifetime
- 1985-03-19 IL IL74646A patent/IL74646A/xx unknown
- 1985-03-19 CA CA476900A patent/CA1263591C/en not_active Expired
- 1985-03-21 NO NO851142A patent/NO171072C/no unknown
- 1985-03-26 AU AU40362/85A patent/AU560315B2/en not_active Ceased
- 1985-03-26 ZA ZA852269A patent/ZA852269B/xx unknown
- 1985-03-27 AT AT85103672T patent/ATE73500T1/de not_active IP Right Cessation
- 1985-03-27 DE DE8585103672T patent/DE3585548D1/de not_active Expired - Lifetime
- 1985-03-27 EP EP85103672A patent/EP0158225B1/de not_active Expired - Lifetime
- 1985-04-02 ES ES541869A patent/ES8607400A1/es not_active Expired
- 1985-04-03 FI FI851352A patent/FI86204C/fi not_active IP Right Cessation
- 1985-04-03 DK DK154685A patent/DK154685A/da not_active Application Discontinuation
- 1985-04-04 IE IE86885A patent/IE58047B1/en not_active IP Right Cessation
- 1985-04-05 JP JP60071263A patent/JPS60232098A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ZA852269B (en) | 1985-11-27 |
| DE3413118A1 (de) | 1985-10-24 |
| NO851142L (no) | 1985-10-07 |
| DK154685A (da) | 1985-10-07 |
| EP0158225A2 (de) | 1985-10-16 |
| JPS60232098A (ja) | 1985-11-18 |
| ES541869A0 (es) | 1986-06-01 |
| IE850868L (en) | 1985-10-06 |
| NO171072B (no) | 1992-10-12 |
| CA1263591A (en) | 1989-12-05 |
| IL74646A (en) | 1989-06-30 |
| NO171072C (no) | 1993-01-20 |
| EP0158225B1 (de) | 1992-03-11 |
| ATE73500T1 (de) | 1992-03-15 |
| AU560315B2 (en) | 1987-04-02 |
| EP0158225A3 (en) | 1987-10-21 |
| IL74646A0 (en) | 1985-06-30 |
| US4758508A (en) | 1988-07-19 |
| ES8607400A1 (es) | 1986-06-01 |
| FI86204B (fi) | 1992-04-15 |
| AU4036285A (en) | 1985-10-10 |
| FI86204C (fi) | 1992-07-27 |
| IE58047B1 (en) | 1993-06-16 |
| JPH0550279B2 (enExample) | 1993-07-28 |
| DK154685D0 (da) | 1985-04-03 |
| DE3585548D1 (de) | 1992-04-16 |
| FI851352L (fi) | 1985-10-07 |
| FI851352A0 (fi) | 1985-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed | ||
| MKLA | Lapsed |
Effective date: 19960605 |