ES8607262A1 - Esteres de aminoacidos y de peptidos cromogenos - Google Patents
Esteres de aminoacidos y de peptidos cromogenosInfo
- Publication number
- ES8607262A1 ES8607262A1 ES541774A ES541774A ES8607262A1 ES 8607262 A1 ES8607262 A1 ES 8607262A1 ES 541774 A ES541774 A ES 541774A ES 541774 A ES541774 A ES 541774A ES 8607262 A1 ES8607262 A1 ES 8607262A1
- Authority
- ES
- Spain
- Prior art keywords
- agents
- esters
- detection
- esterolytic
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 5
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 3
- 102000035195 Peptidases Human genes 0.000 title abstract 2
- 108091005804 Peptidases Proteins 0.000 title abstract 2
- 230000000058 esterolytic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title 1
- 238000004458 analytical method Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- SWEICGMKXPNXNU-UHFFFAOYSA-N 1,2-dihydroindazol-3-one Chemical class C1=CC=C2C(O)=NNC2=C1 SWEICGMKXPNXNU-UHFFFAOYSA-N 0.000 abstract 1
- -1 amino acid esters Chemical class 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 150000003557 thiazoles Chemical class 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ESTERES DE AMINOACIDOS Y DE PEPTIDOS CROMOGENOS, DE FORMULA (I), EN LA QUE X1 Y X2 REPRESENTAN NITROGENO O AZUFRE; R1 ES HIDROGENO O ALQUILO C1-6; R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES; A ES UN RESTO DE AMINOACIDO O DE PEPTIDO; Y G ES HIDROGENO O GRUPO PROTECTOR DE NITROGENO. COMPRENDE LA REACCION DE UN FENOL DE FORMULA (II) CON UN COMPUESTO DE FORMULA G-A-OH, EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), O BIEN CON DERIVADOS REACTIVOS DE LOS MISMOS, COMO CLORUROS DE ACIDO O ANHIDRIDOS MIXTOS. LA REACCION SE LLEVA A CABO SEGUN METODOS CONVENCIONALES EN LA QUIMICA DE LOS PEPTIDOS. ESTOS COMPUESTOS TIENEN APLICACIONES EN LA DIAGNOSIS DE LAS ENFERMEDADES DE LOS RIÑONES Y DEL TRACTO UROGENITAL POR DETERMINACIONES DE LEUCOCITOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843413077 DE3413077A1 (de) | 1984-04-06 | 1984-04-06 | Chromogene aminosaeure- und peptidester, verfahren zu deren herstellung, verwendung dieser verbindungen in analysenverfahren sowie mittel zum nachweis esterolytischer und/oder proteolytischer enzyme |
Publications (2)
Publication Number | Publication Date |
---|---|
ES541774A0 ES541774A0 (es) | 1986-06-01 |
ES8607262A1 true ES8607262A1 (es) | 1986-06-01 |
Family
ID=6232916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541774A Expired ES8607262A1 (es) | 1984-04-06 | 1985-03-29 | Esteres de aminoacidos y de peptidos cromogenos |
Country Status (6)
Country | Link |
---|---|
US (2) | US4723020A (es) |
EP (1) | EP0157360B1 (es) |
JP (2) | JPS60231658A (es) |
AU (1) | AU556832B2 (es) |
DE (2) | DE3413077A1 (es) |
ES (1) | ES8607262A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3629175A1 (de) * | 1986-08-28 | 1988-03-17 | Behringwerke Ag | Chromogene verbindungen, verfahren zu deren herstellung und ihre verwendung |
EP0661280A1 (en) * | 1993-12-29 | 1995-07-05 | Kyoto Daiichi Kagaku Co., Ltd. | Novel amino acid ester and reagent composition for detecting leucocytes or elastase in body liquid |
US5464739A (en) | 1994-08-22 | 1995-11-07 | Bayer Corporation | Composition method for determining the presence of leukocyte cells, esterase or protease in a test sample |
CA2161574A1 (en) * | 1994-11-15 | 1996-05-16 | James Noffsinger | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid |
US6528652B1 (en) * | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
US6709868B2 (en) * | 2002-05-20 | 2004-03-23 | Portascience Inc. | Method and apparatus for measuring white blood cell count |
US7611863B2 (en) * | 2004-01-08 | 2009-11-03 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Selective staining of biomembranes using voltage-sensitive dyes |
EP1553396A3 (en) * | 2004-01-08 | 2005-09-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Selective staining of biomembranes using voltage-sensitive dyes |
US7504235B2 (en) | 2005-08-31 | 2009-03-17 | Kimberly-Clark Worldwide, Inc. | Enzyme detection technique |
US8003399B2 (en) * | 2005-08-31 | 2011-08-23 | Kimberly-Clark Worldwide, Inc. | Nitrite detection technique |
WO2007027353A2 (en) * | 2005-08-31 | 2007-03-08 | Kimberly-Clark Worldwide, Inc. | Detection of proteases secreted from pathogenic microorganisms |
US8758989B2 (en) * | 2006-04-06 | 2014-06-24 | Kimberly-Clark Worldwide, Inc. | Enzymatic detection techniques |
US8044257B2 (en) * | 2006-10-30 | 2011-10-25 | Kimberly-Clark Worldwide, Inc. | Absorbent article containing lateral flow assay device |
US7935538B2 (en) * | 2006-12-15 | 2011-05-03 | Kimberly-Clark Worldwide, Inc. | Indicator immobilization on assay devices |
US7897360B2 (en) | 2006-12-15 | 2011-03-01 | Kimberly-Clark Worldwide, Inc. | Enzyme detection techniques |
US8043272B2 (en) * | 2007-04-30 | 2011-10-25 | Kimberly-Clark Worldwide, Inc. | Collection and testing of infant urine using an absorbent article |
US20080269707A1 (en) * | 2007-04-30 | 2008-10-30 | Kimberly-Clark Worldwide, Inc. | Lateral Flow Device for Attachment to an Absorbent Article |
US9103796B2 (en) * | 2007-12-14 | 2015-08-11 | Kimberly-Clark Worldwide, Inc. | Multi-layered devices for analyte detection |
US20100290948A1 (en) * | 2009-05-15 | 2010-11-18 | Xuedong Song | Absorbent articles capable of indicating the presence of urinary tract infections |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1128371A (en) * | 1965-10-04 | 1968-09-25 | Miles Lab | Diagnostic composition |
US3929815A (en) * | 1973-12-19 | 1975-12-30 | Gulf Research Development Co | Hydroxy-, alkoxy-, and alkylcarbamoyloxy-2,1-benzisothiazoles |
DE2854987A1 (de) * | 1978-12-20 | 1980-06-26 | Boehringer Mannheim Gmbh | Diagnostische mittel zum nachweis proteolytischer enzyme und dafuer geeignete chromogene |
DE3017721A1 (de) * | 1980-05-09 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Mittel zum nachweis esterolytischer und/oder proteolytischer enzyme und dafuer geeignete substrate |
US4704460A (en) * | 1984-04-06 | 1987-11-03 | Miles Laboratories, Inc. | Novel compounds for detecting the presence of hydrolytic analytes in a test sample |
-
1984
- 1984-04-06 DE DE19843413077 patent/DE3413077A1/de not_active Withdrawn
-
1985
- 1985-03-11 US US06/710,623 patent/US4723020A/en not_active Expired - Lifetime
- 1985-03-20 AU AU40142/85A patent/AU556832B2/en not_active Ceased
- 1985-03-27 DE DE8585103667T patent/DE3583761D1/de not_active Expired - Fee Related
- 1985-03-27 EP EP85103667A patent/EP0157360B1/de not_active Expired - Lifetime
- 1985-03-29 ES ES541774A patent/ES8607262A1/es not_active Expired
- 1985-04-04 JP JP60070161A patent/JPS60231658A/ja active Granted
-
1987
- 1987-03-05 JP JP62048995A patent/JPS62215400A/ja active Granted
- 1987-08-27 US US07/090,009 patent/US4806423A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU556832B2 (en) | 1986-11-20 |
EP0157360A3 (en) | 1988-05-04 |
DE3413077A1 (de) | 1985-10-17 |
JPS62215400A (ja) | 1987-09-22 |
EP0157360A2 (de) | 1985-10-09 |
ES541774A0 (es) | 1986-06-01 |
DE3583761D1 (de) | 1991-09-19 |
AU4014285A (en) | 1985-10-10 |
JPH0244517B2 (es) | 1990-10-04 |
EP0157360B1 (de) | 1991-08-14 |
JPS6245227B2 (es) | 1987-09-25 |
US4806423A (en) | 1989-02-21 |
JPS60231658A (ja) | 1985-11-18 |
US4723020A (en) | 1988-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20060225 |